Large rocks and a sandy beach with sparse vegetation.

Isla Santa María Holiday Rentals

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Our top choices for Isla Santa María holiday rentals

1. Modern apartment with 18 feet ceilings and private terrace with view to a park

Modern apartment with 18 feet ceilings and private terrace with view to a park
Puerto Ayora
10.0 out of 10, Exceptional, (24 reviews)
"I highly recommend you stay here. Its is beautiful and also away from the crowd noise."
United States
Richard
The price is NZ$256
29 Aug - 30 Aug
Modern apartment with 18 feet ceilings and private terrace with view to a park

2. Torre Mar Galapagos Boutique Suites

Torre Mar Galapagos Boutique Suites
3.0 star property
Puerto Ayora
9.4 out of 10, Exceptional, (27 reviews)
"The host was so nice, kind, and friendly."
United States
Maho
The price is NZ$220
18 Sept - 19 Sept
Torre Mar Galapagos Boutique Suites

3. Suites

Suites
3.0 star property
Puerto Ayora
9.4 out of 10, Exceptional, (24 reviews)
"Check was early and friendly staff Room was super clean and comfortable"
United States
Judy
The price is NZ$140
29 Aug - 30 Aug
Suites

4. Villa Galapagos

Villa Galapagos
2.5 star property
Puerto Ayora
6.0 out of 10, (1 review)
"着いて早々にダブルブッキングがわかった。これは施設というよりも、貴社のシステムの問題。前回も宿泊名簿に名前がなかったこともあり、強く改善をもとめる。"
Japan
アオアシカツオドリ
The price is NZ$161
29 Aug - 30 Aug
Villa Galapagos

5. Colmena Apartment in downtown Puerto Ayora, Santa Cruz

Colmena Apartment in downtown Puerto Ayora, Santa Cruz
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"We had an excellent experience at Five minutes from the malecon Santa Cruz - Puerto Ayora. The property is brand new, very secure, and perfectly located. What truly made our stay special was our host, Gaby. She was always available, attentive, and ready to help us with anything we needed. Had we known about this place earlier, we would have booked it for our entire stay in Santa Cruz. We highly recommend this accommodation to anyone visiting the island — it’s a gem!"
United States
jacques
The price is NZ$298
29 Aug - 30 Aug
Colmena Apartment in downtown Puerto Ayora, Santa Cruz

6. Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora

Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora
Puerto Ayora
10.0 out of 10, Exceptional, (2 reviews)
The price is NZ$391
25 Sept - 26 Sept
Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora

7. TWO Bedrooms Apartment ON THE Ground Floor IN Ariana`s Galapagos Hostal

TWO Bedrooms Apartment ON THE Ground Floor IN Ariana`s Galapagos Hostal
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"We enjoyed our 6-night stay at Ariana's. The apartment was large and comfortable. Bedroom air conditioners were whisper quiet. We especially enjoyed the rooftop terrace with its soft breezes. It’s a 20 minute walk to the big tortoise statue and a few minutes more to the Mlecon, or a 2 taxi ride."
Canada
Dean P.
The price is NZ$167
29 Aug - 30 Aug
TWO Bedrooms Apartment ON THE Ground Floor IN Ariana`s Galapagos Hostal

8. Suite with spectacular ocean view, you will wake up to the sound of the sea.

Suite with spectacular ocean view, you will wake up to the sound of the sea.
Puerto Ayora
8.0 out of 10, Very good, (1 review)
The price is NZ$277
25 Sept - 26 Sept
Suite with spectacular ocean view, you will wake up to the sound of the sea.

9. Spacious 6-bedroom building in superb Puerto Ayora with AC and no AC

Spacious 6-bedroom building in superb Puerto Ayora with AC and no AC
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"Stay was great and I really enjoy Daniel’s helpful service— can’t wait to come back and stay again!"
United States
Will L.
The price is NZ$227
8 Sept - 9 Sept
Spacious 6-bedroom building in superb Puerto Ayora with AC and no AC

10. Galapagos Family Vacation 3 BR. Centrally located and Ocean View

Galapagos Family Vacation 3 BR. Centrally located and Ocean View
Puerto Ayora
10.0 out of 10, Exceptional, (28 reviews)
"Great communication with host, gave us information ahead of time for laundry services and taxi. Clean and wonderful property close to everything and great views."
United States
Amanda
The price is NZ$811
23 Sept - 24 Sept
Galapagos Family Vacation 3 BR. Centrally located and Ocean View

11. Galapagos Coliving Ecuador Casa Tuna

Galapagos Coliving Ecuador Casa Tuna
3.0 star property
Puerto Ayora
2.0 out of 10, (1 review)
"Beware of this scam, the owner did not receive our reservstion nor the money!"
United States
Maya
The price is NZ$284
29 Aug - 30 Aug
Galapagos Coliving Ecuador Casa Tuna

12. Near Tortuga Bay Beach

Near Tortuga Bay Beach
Puerto Ayora
The price is NZ$130
25 Sept - 26 Sept
Near Tortuga Bay Beach

13. TWO Bedrooms Apartment ON THE First Floor Forest View

TWO Bedrooms Apartment ON THE First Floor Forest View
Puerto Ayora
The price is NZ$167
29 Aug - 30 Aug
TWO Bedrooms Apartment ON THE First Floor Forest View

14. A centrally located suite in Santa Cruz within easy reach of everything

A centrally located suite in Santa Cruz within easy reach of everything
Puerto Ayora
The price is NZ$126
25 Sept - 26 Sept
A centrally located suite in Santa Cruz within easy reach of everything

15. Near the sea-Darwin Apartment

Near the sea-Darwin Apartment
Puerto Ayora
The price is NZ$169
29 Aug - 30 Aug
Near the sea-Darwin Apartment

16. NEAR THE SEE-DARWIN APARTMENT

NEAR THE SEE-DARWIN APARTMENT
Puerto Ayora
The price is NZ$207
29 Aug - 30 Aug
NEAR THE SEE-DARWIN APARTMENT

17. Galapagos Apartment-Darwin

Galapagos Apartment-Darwin
Puerto Ayora
The price is NZ$149
29 Aug - 30 Aug
Galapagos Apartment-Darwin

18. Downtown Apartment

Downtown Apartment
Puerto Ayora
Downtown Apartment

19. FAMILY SUITE in Puerto Ayora

FAMILY SUITE in Puerto Ayora
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"Great lodging with effective space for multiple groups of travelers. Location is perfect, off the tourist path, and easy to access by any taxis in Puerto Arroyo (just say you want to go to Parque Cascada). Groceries are available anywhere near the house, better produce quality found in the shops on Baltra Ave. Property manager is easy to communicate with and responds instantly."
United States
Nathan M.
The price is NZ$380
29 Aug - 30 Aug
FAMILY SUITE in Puerto Ayora

20. Island life Duplex great for groups

Island life Duplex great for groups
Puerto Ayora, Santa Cruz Island
The price is NZ$605
25 Sept - 26 Sept
Island life Duplex great for groups
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Isla Santa María Hotel Reviews

Find out more about Isla Santa María

You always said you would go on a dream holiday someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannonball into the deep end. Go ahead, unplug and unwind in style. When you book one of our Isla Santa María holiday rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your holiday just got upgraded.

As much as you love your vacation rental, it’s always good to get out and explore to soak up Isla Santa María. Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in Isla Santa María. Seeing all the best attractions is bound to make you fall in love with Isla Santa María. Who knows, you may even be tempted to extend your stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true. 

It’s your escape so why share it? You deserve your own slice of paradise. Booking your holiday rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in Isla Santa María short-term rentals, that won’t be hard to do.

Frequently asked questions

Can I find holiday rentals in Isla Santa María?

Yes, there are holiday rentals in Isla Santa María close to Galápagos National Park, or you can select a more secluded option if you're looking for a relaxing stay.

What are some of the best holiday rentals that Isla Santa María has to offer?

Villa Galapagos: This holiday home rental outside of Isla Santa María is located near the beach, and offers a private garden, air conditioning and daily housekeeping to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop and a microwave.

What’s there to see and do in Isla Santa María?

Family-friendly attractions include Galápagos National Park, whereas Post Office Bay is a spot to enjoy the outdoors. Other places in town to visit include Punta Suarez.

What’s a holiday rental in Isla Santa María like?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in Isla Santa María. Holiday rentals offer amenities such as laundry facilities and kitchens so you'll feel just like you're staying in your own home. If you're concerned about cleanliness, holiday rentals can offer a sense of seclusion away from public hotel lifts and busy concierge desks while still allowing you the experience of travel. You'll also have more space in a holiday rental than in a standard hotel, which is another reason why a holiday rental is a great option for a family trip.