South Central Houston Travel Guide

Tourist Guide

A water feature with multiple tiers and a circular viewing platform at the top.
A city skyline at night with illuminated skyscrapers and a large brick plaza in the foreground.
A train on tracks with graffiti on a nearby building.
A park with a gazebo, a fountain, and tall buildings in the background.
A water feature with a cascading waterfall, a grassy hill, and a tall building in the background.

Stay near popular South Central Houston attractions

A large historic building with a red roof and arched windows, surrounded by a well-maintained garden and a clear blue sky.

Rice University

8.6/10 (1,772 reviews)
Walk around the campus of Rice University, a top university in Houston. Experience the area's acclaimed theatre scene and fascinating museums.
See properties

Activities

Picture 3 for Activity Houston: Space Center Houston Admission Ticket

Houston: Space Center Houston Admission Ticket

NZ$52
per adult
92% of travellers recommend
Houston: Space Center Houston Admission Ticket
Houston Museum of Natural Science: Cockrell Butterfly Center

Houston Museum of Natural Science: Butterfly Center Ticket

NZ$26
per adult
100% of travellers recommend
Houston Museum of Natural Science: Butterfly Center Ticket
The Official Houston City Tour

NASA's Space Center & Official Houston City Tour with tickets

NZ$166
per adult
92% of travellers recommend
NASA's Space Center & Official Houston City Tour with tickets
HOP ON- HOP OFF

Houston's Official City & Mural Tour!

NZ$67
per adult
88% of travellers recommend
Houston's Official City & Mural Tour!
Houston: Guided City Tour by an Open-Top Double Decker Bus

Houston: Guided City Tour by an Open-Top Double Decker Bus

NZ$67
per adult
98% of travellers recommend
Houston: Guided City Tour by an Open-Top Double Decker Bus
Viral Drip Bear Painting Experience

Viral Drip Bear Painting Experience

NZ$59
per adult
Viral Drip Bear Painting Experience
See all activities in Houston

Our pick of the best South Central Houston Hotel Deals

Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street Houston TX
The price is NZ$588 per night from 29 Sept to 30 Sept
NZ$588
29 Sept - 30 Sept
includes taxes & fees
Stay at this luxury hotel in Houston. Enjoy free Wi-Fi, a full-service spa and breakfast (surcharge). Our guests praise the helpful staff in their reviews. Popular ...
Hotel Zaza Houston Museum District
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St Houston TX
The price is NZ$221 per night from 11 Oct to 12 Oct
NZ$221
11 Oct - 12 Oct
includes taxes & fees
Stay at this luxury hotel in Houston. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in their reviews. ...
Hilton Houston Plaza/Medical Center
The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District

4 out of 5
1709 DRYDEN ROAD Houston TX
The price is NZ$318 per night from 11 Oct to 12 Oct
NZ$318
11 Oct - 12 Oct
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service and a 24-hour health club. Our guests praise the helpful staff and ...
9.2/10 Wonderful! (1,208 reviews)
"Everything 10/10"

Reviewed on 25 Sept 2026

The Westin Houston Medical Center/Museum District
InterContinental Houston by IHG

InterContinental Houston by IHG

4 out of 5
6750 Main St Houston TX
The price is NZ$372 per night from 25 Oct to 26 Oct
NZ$372
25 Oct - 26 Oct
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy free Wi-Fi, breakfast (surcharge) and a free local area shuttle. Our guests praise the helpful staff and ...
9.4/10 Exceptional! (1,007 reviews)
"Hotel provides shuttle service within 2 miles, very helpful during the hot day."

Reviewed on 23 Sept 2026

InterContinental Houston by IHG
Extended Stay America Suites Houston Med Ctr Braeswood Bl

Extended Stay America Suites Houston Med Ctr Braeswood Bl

2.5 out of 5
1301 Braeswood Blvd Houston TX
The price is NZ$160 per night from 27 Sept to 28 Sept
NZ$160
27 Sept - 28 Sept
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the clean rooms in their reviews. Popular ...
Extended Stay America Suites Houston Med Ctr Braeswood Bl
Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District

4 out of 5
6580 Fannin Street Houston TX
The price is NZ$409 per night from 17 Oct to 18 Oct
NZ$409
17 Oct - 18 Oct
includes taxes & fees
Stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), a free local area shuttle and room service. Our guests praise the helpful staff ...
9/10 Wonderful! (1,000 reviews)
"Convenient"

Reviewed on 21 Sept 2026

Houston Marriott Medical Center/Museum District
See all 1,275 properties in South Central Houston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our guide on where to stay in South Central Houston

Find the best South Central Houston areas for the activities you enjoy most. Learn more about South Central Houston
Learn more about South Central Houston
A sculpture garden with abstract art pieces in a city park.

Downtown Houston

Gourmet restaurants acclaimed theatres and top sights from Daikin Park to Toyota Center – discover Downtown Houston, a destination also famous for its sports teams.

A tall, modern building with a unique, vertical design, surrounded by trees and a partly cloudy sky.

The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.

A cityscape with dense high-rise buildings, a river, and surrounding greenery.

Texas Medical Center

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

A modern building with a covered outdoor area and a circular garden feature.

Montrose

Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

A bridge with the words "Welcome to Downtown Houston" and a star emblem.

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.

South Central Houston Travel Guide

Choose two or more items and save on your trip:

Explore a world of travel with Expedia