A coastal landscape with clear turquoise waters, sandy beaches, and volcanic hills.

Santa Cruz Holiday Rentals

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Our top choices for Santa Cruz holiday rentals

An outdoor patio with a wooden table and benches, surrounded by plants and a wooden fence.

1. Torre Mar Galapagos Boutique Suites

Torre Mar Galapagos Boutique Suites
3.0 star property
Puerto Ayora
9.4 out of 10, Exceptional, (27 reviews)
"The host was so nice, kind, and friendly."
United States
Maho
The price is NZ$220
18 Sept - 19 Sept
Torre Mar Galapagos Boutique Suites
A couple sitting on a wicker sofa outdoors, with a table between them holding breakfast items and a book titled "GALAPAGOS".

2. Modern apartment with 18 feet ceilings and private terrace with view to a park

Modern apartment with 18 feet ceilings and private terrace with view to a park
Puerto Ayora
10.0 out of 10, Exceptional, (24 reviews)
"I highly recommend you stay here. Its is beautiful and also away from the crowd noise."
United States
Richard
The price is NZ$256
29 Aug - 30 Aug
Modern apartment with 18 feet ceilings and private terrace with view to a park
A patio with a round table and chairs, a blue umbrella, and a potted plant.

3. Suites

Suites
3.0 star property
Puerto Ayora
9.4 out of 10, Exceptional, (24 reviews)
"Check was early and friendly staff Room was super clean and comfortable"
United States
Judy
The price is NZ$140
29 Aug - 30 Aug
Suites
A modern kitchen with a dining table, chairs, pendant lights, a refrigerator, and a large window with curtains.

4. Colmena Apartment in downtown Puerto Ayora, Santa Cruz

Colmena Apartment in downtown Puerto Ayora, Santa Cruz
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"We had an excellent experience at Five minutes from the malecon Santa Cruz - Puerto Ayora. The property is brand new, very secure, and perfectly located. What truly made our stay special was our host, Gaby. She was always available, attentive, and ready to help us with anything we needed. Had we known about this place earlier, we would have booked it for our entire stay in Santa Cruz. We highly recommend this accommodation to anyone visiting the island — it’s a gem!"
United States
jacques
The price is NZ$298
29 Aug - 30 Aug
Colmena Apartment in downtown Puerto Ayora, Santa Cruz
A modern living room with a large table, a sofa, and a TV mounted on the wall.

5. Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora

Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora
Puerto Ayora
10.0 out of 10, Exceptional, (2 reviews)
"The place is perfect in every way, clean , spacious, great kitchen, comfortable beds, also the laundry facility is so helpful for longer stay. The host communication is excellent, immediate responds, great recommendations for the activities and local eats, location is also good , 10-15 minutes to walk to town center. we enjoyed our stay very much. highly recommend this place."
United States
Lihua
The price is NZ$365
2 Sept - 3 Sept
Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora
A modern living room with a sofa, ottoman, and coffee table, large windows, and a wooden ceiling beam.

6. Galapagos Coliving Ecuador Casa Tuna

Galapagos Coliving Ecuador Casa Tuna
3.0 star property
Puerto Ayora
2.0 out of 10, (1 review)
"Beware of this scam, the owner did not receive our reservstion nor the money!"
United States
Maya
The price is NZ$284
29 Aug - 30 Aug
Galapagos Coliving Ecuador Casa Tuna
A building with a white exterior, wooden vertical elements, and a cactus plant in the foreground.

7. Villa Galapagos

Villa Galapagos
2.5 star property
Puerto Ayora
6.0 out of 10, (1 review)
"着いて早々にダブルブッキングがわかった。これは施設というよりも、貴社のシステムの問題。前回も宿泊名簿に名前がなかったこともあり、強く改善をもとめる。"
Japan
アオアシカツオドリ
The price is NZ$161
25 Sept - 26 Sept
Villa Galapagos
An aerial view of a marina with numerous boats docked, a pier with umbrellas, and a small building with a red roof.

8. Galapagos Family Vacation 3 BR. Centrally located and Ocean View

Galapagos Family Vacation 3 BR. Centrally located and Ocean View
Puerto Ayora
10.0 out of 10, Exceptional, (28 reviews)
"Great communication with host, gave us information ahead of time for laundry services and taxi. Clean and wonderful property close to everything and great views."
United States
Amanda
The price is NZ$811
23 Sept - 24 Sept
Galapagos Family Vacation 3 BR. Centrally located and Ocean View
A bedroom with a bed, a chair, and a view of the sea through large windows.

9. Suite with spectacular ocean view, you will wake up to the sound of the sea.

Suite with spectacular ocean view, you will wake up to the sound of the sea.
Puerto Ayora
8.0 out of 10, Very good, (1 review)
The price is NZ$258
3 Sept - 4 Sept
Suite with spectacular ocean view, you will wake up to the sound of the sea.
A multi-story building with a curved facade, balconies with glass railings, and a staircase leading to the upper floors.

10. TWO Bedrooms Apartment ON THE Ground Floor IN Ariana`s Galapagos Hostal

TWO Bedrooms Apartment ON THE Ground Floor IN Ariana`s Galapagos Hostal
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"We enjoyed our 6-night stay at Ariana's. The apartment was large and comfortable. Bedroom air conditioners were whisper quiet. We especially enjoyed the rooftop terrace with its soft breezes. It’s a 20 minute walk to the big tortoise statue and a few minutes more to the Mlecon, or a 2 taxi ride."
Canada
Dean P.
The price is NZ$167
29 Aug - 30 Aug
TWO Bedrooms Apartment ON THE Ground Floor IN Ariana`s Galapagos Hostal
A hotel room with a bed, a sofa, a dresser, a mirror, and a view of an outdoor patio with a table and chairs.

11. Spacious 6-bedroom building in superb Puerto Ayora with AC and no AC

Spacious 6-bedroom building in superb Puerto Ayora with AC and no AC
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"Stay was great and I really enjoy Daniel’s helpful service— can’t wait to come back and stay again!"
United States
Will L.
The price is NZ$227
13 Sept - 14 Sept
Spacious 6-bedroom building in superb Puerto Ayora with AC and no AC
An outdoor patio with artificial grass, a wooden bench, and a hammock.

12. FAMILY SUITE in Puerto Ayora

FAMILY SUITE in Puerto Ayora
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"Great lodging with effective space for multiple groups of travelers. Location is perfect, off the tourist path, and easy to access by any taxis in Puerto Arroyo (just say you want to go to Parque Cascada). Groceries are available anywhere near the house, better produce quality found in the shops on Baltra Ave. Property manager is easy to communicate with and responds instantly."
United States
Nathan M.
The price is NZ$380
29 Aug - 30 Aug
FAMILY SUITE in Puerto Ayora
An outdoor patio with a wooden table and benches, surrounded by plants and a wooden fence.

13. Island life Duplex great for groups

Island life Duplex great for groups
Puerto Ayora, Santa Cruz Island
The price is NZ$605
25 Sept - 26 Sept
Island life Duplex great for groups

14. NEAR THE SEE-DARWIN APARTMENT

NEAR THE SEE-DARWIN APARTMENT
Puerto Ayora
The price is NZ$207
29 Aug - 30 Aug
NEAR THE SEE-DARWIN APARTMENT
A bedroom with a bed, a wooden wardrobe, a blue laundry basket, and a window with curtains.

15. TWO Bedrooms Apartment ON THE First Floor Forest View

TWO Bedrooms Apartment ON THE First Floor Forest View
Puerto Ayora
The price is NZ$167
25 Sept - 26 Sept
TWO Bedrooms Apartment ON THE First Floor Forest View
A rooftop terrace with a wooden bench, a potted plant, and a view of the cityscape and mountains.

16. 2-bedroom apartment with AC, WiFi in fabulous Puerto Ayora

2-bedroom apartment with AC, WiFi in fabulous Puerto Ayora
Puerto Ayora
The price is NZ$148
31 Aug - 1 Sept
2-bedroom apartment with AC, WiFi in fabulous Puerto Ayora
A compact kitchen with a gas stove, a sink, a refrigerator, and a dining area with chairs.

17. Near the sea-Darwin Apartment

Near the sea-Darwin Apartment
Puerto Ayora
Near the sea-Darwin Apartment

18. Galapagos Apartment-Darwin

Galapagos Apartment-Darwin
Puerto Ayora
The price is NZ$149
29 Aug - 30 Aug
Galapagos Apartment-Darwin
A hotel room with two beds, each with a wooden headboard, white and brown bedding, and a nightstand with a lamp. There are wall-mounted air conditioning units and three framed pictures depicting ocean scenes.

19. Perfect for family or friends 4 Bedroom 2 bath

Perfect for family or friends 4 Bedroom 2 bath
Puerto Ayora, Santa Cruz Island
The price is NZ$748
29 Aug - 30 Aug
Perfect for family or friends 4 Bedroom 2 bath
A bedroom with a bed, two rugs, a nightstand, a picture on the wall, and a window with curtains.

20. Near Tortuga Bay Beach

Near Tortuga Bay Beach
Puerto Ayora
The price is NZ$130
29 Aug - 30 Aug
Near Tortuga Bay Beach
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Santa Cruz Hotel Reviews

Hotel Ninfa

Hotel Ninfa

10/10 Excellent
"Staff was really friendly and helpful"
Kleber 4-night trip
Posted 5 days ago
Hotel Ninfa

Find out more about Santa Cruz

Everything you need to know about Santa Cruz holiday rentals

Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Santa Cruz holiday rental for you. At Expedia, you can take your pick from private holiday homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa Cruz holiday rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

Santa Cruz holiday rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santa Cruz. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Santa Cruz holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Santa Cruz holiday rentals we have selected for you start as low as NZ$140 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Santa Cruz rentals

At Expedia, we put the best Santa Cruz holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Santa Cruz rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa Cruz holiday.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa Cruz. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.