Lodging Image

Book New Madrid County Hotels

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Top Cities in New Madrid County

A tree with sunlight filtering through its leaves, creating a warm glow.
HotelsHotels

Sikeston

Sikeston
A cannon on a brick platform by a river, with a steamboat in the background.
HotelsHotels

New Madrid

New Madrid

Check prices for these dates

This weekend
23 Oct - 25 Oct
Next weekend
30 Oct - 1 Nov

Filter by

Property class

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for New Madrid County hotels

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.

1. Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.6 out of 10, Exceptional, (1,000 reviews)
"Awesome place will be staying in more of them"
United States
Tim
The price is NZ$190
includes taxes & fees
8 Nov - 9 Nov
Drury Inn & Suites Sikeston, MO
A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.

2. Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (647 reviews)
"Great place"
United States
Lori
The price is NZ$190
includes taxes & fees
22 Nov - 23 Nov
Hampton Inn Sikeston
A hotel lobby with a central bar area, multiple dining tables and chairs, large windows, and a patterned carpet.

3. Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very good, (1,002 reviews)
"Clean rooms, great parking, very nice staff"
United States
Shelley
The price is NZ$160
includes taxes & fees
15 Nov - 16 Nov
Best Western Plus Sikeston I-55
A modern hotel room with a large bed, a smaller bed, a desk, and a chair. There is a window with curtains and a painting on the wall.

4. Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
2.0 star property
Sikeston
7.4 out of 10, Good, (1,000 reviews)
"This was a very good value. It has been the best hotel I've stayed at in awhile."
United States
David
The price is NZ$133
includes taxes & fees
1 Nov - 2 Nov
Days Inn and Suites by Wyndham Sikeston
A hotel room with a bed, a desk with a chair, a TV, two bedside lamps, and a large window.

5. Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
2.0 star property
Sikeston
7.0 out of 10, Good, (688 reviews)
"It is a clean place, and we enjoyed our stay"
United States
Laura
The price is NZ$115
includes taxes & fees
29 Oct - 30 Oct
Super 8 by Wyndham Sikeston/Miner Area
A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.

6. Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.8 out of 10, Excellent, (518 reviews)
"I have always have a great stay each time I’ve been here. Beds comfortable and rooms very clean."
United States
Melissa
The price is NZ$182
includes taxes & fees
22 Nov - 23 Nov
Holiday Inn Express & Suites Sikeston Southwest by IHG
A hotel room with a large bed, a desk with a computer, a chair, a window with a view, and a wall-mounted TV.

7. Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very good, (827 reviews)
"Very clean property and the staff were very accommodating."
United States
Craig
The price is NZ$127
includes taxes & fees
5 Nov - 6 Nov
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.

8. Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (118 reviews)
"Friendly staff, great breakfast, nice amenities"
United States
Roslyn
The price is NZ$202
includes taxes & fees
1 Nov - 2 Nov
Fairfield Inn & Suites by Marriott Sikeston
A hotel room with two beds, a desk, a chair, a TV, and a mirror.

9. Country Yard Inn and Suite

Country Yard Inn and Suite
2.0 star property
Sikeston
6.8 out of 10, (161 reviews)
"Great clean place to stay at"
United States
William
The price is NZ$111
includes taxes & fees
23 Oct - 24 Oct
Country Yard Inn and Suite
A modern hotel room with a large bed, bedside tables, a nightstand, a wall-mounted lamp, a window with a view of a road, and a wall-mounted air conditioner.

10. Super 8 By Wyndham Marston

Super 8 By Wyndham Marston
2.0 star property
Marston
8.0 out of 10, Very good, (80 reviews)
"Got there late and staff was very helpful. Room was clean and comfortable"
United States
Wendy
The price is NZ$113
includes taxes & fees
15 Nov - 16 Nov
Super 8 By Wyndham Marston
A Comfort Inn & Suites hotel with a clear entrance, a covered parking area, and a sign indicating a 12' clearance.

11. Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very good, (317 reviews)
"The room was nice"
United States
Fred
The price is NZ$159
includes taxes & fees
15 Nov - 16 Nov
Comfort Inn & Suites Sikeston I-55
Property amenity

12. TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
3.0 star property
Sikeston
9.2 out of 10, Wonderful, (27 reviews)
"Great location"
United States
Rubin
The price is NZ$218
includes taxes & fees
12 Nov - 13 Nov
TownePlace Suites by Marriott Sikeston
A hotel room with two beds, a desk, a chair, and a window with a view of the outdoors.

13. Travel Inn Marston I-55 by Hotel O

Travel Inn Marston I-55 by Hotel O
2.5 star property
Marston
5.8 out of 10, (129 reviews)
"Quiet safe area."
United States
Frank
The price is NZ$84
includes taxes & fees
23 Oct - 24 Oct
Travel Inn Marston I-55 by Hotel O
A bedroom with a bed, bedside table, lamp, and a view of the bathroom.

14. OYO Malden Airport Inn

OYO Malden Airport Inn
2.5 star property
Malden
6.4 out of 10, (79 reviews)
"Clean room, cleaning staff friendly, AC working, overflowing dumpster."
United States
James
OYO Malden Airport Inn
A single-story house with a gabled roof, a front porch with two chairs, and a front door with a decorative glass panel.

15. Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!

Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!
New Madrid
10.0 out of 10, Exceptional, (1 review)
"The host was very quick to respond and so great to work with for on our stay. "
United States
Jessica S.
The price is NZ$645
includes taxes & fees
21 Nov - 22 Nov
Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!
A hotel room with a dark wooden desk, a television, a lamp, a chair, and a mirror on the wall.

16. Reelfoot Lake Inn

Reelfoot Lake Inn
2.0 star property
Tiptonville
7.2 out of 10, Good, (515 reviews)
"It’s an older place but very clean"
United States
Danny
The price is NZ$112
includes taxes & fees
22 Nov - 23 Nov
Reelfoot Lake Inn
A covered outdoor area with a grill, chairs, and a table.

17. Come and relax at the Refuge at beautiful Reelfoot Lake!

Come and relax at the Refuge at beautiful Reelfoot Lake!
Hornbeak
9.4 out of 10, Exceptional, (37 reviews)
"Location was great. We were down for a few days fishing."
United States
Andrew
The price is NZ$416
includes taxes & fees
5 Nov - 6 Nov
Come and relax at the Refuge at beautiful Reelfoot Lake!
A two-story building with a porch, a sign indicating 'The Duck Nest Lodge,' and a mailbox labeled 'Couchmen.'

18. Great location just across the street from Reelfoot Lake close to boat ramps

Great location just across the street from Reelfoot Lake close to boat ramps
Hornbeak
9.8 out of 10, Exceptional, (99 reviews)
"Very welcoming, great amenities and accomodations. "
United States
Allan K.
The price is NZ$295
includes taxes & fees
25 Oct - 26 Oct
Great location just across the street from Reelfoot Lake close to boat ramps
A kitchen with wooden cabinets, a stainless steel refrigerator, a built-in oven, and a large window.

19. 3-bedroom house in charming Tiptonville with cool AC and washer and dryer

3-bedroom house in charming Tiptonville with cool AC and washer and dryer
Tiptonville
10.0 out of 10, Exceptional, (2 reviews)
"Clean very nice home, great for pets would definitely stay again"
United States
Patsy W.
The price is NZ$414
includes taxes & fees
29 Oct - 30 Oct
3-bedroom house in charming Tiptonville with cool AC and washer and dryer
A wooden dock extending into calm water, with a covered seating area and a cooler on the right.

20. Dave shallow lake lodge at reelfoot lake 2 story cabin 14 lakefront property

Dave shallow lake lodge at reelfoot lake 2 story cabin 14 lakefront property
Tiptonville
10.0 out of 10, Exceptional, (3 reviews)
"Had a great time. Everything was perfect."
United States
james k.
The price is NZ$535
includes taxes & fees
25 Oct - 26 Oct
Dave shallow lake lodge at reelfoot lake 2 story cabin 14 lakefront property
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Hotels recommended for families in New Madrid County

A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (647)
The price is NZ$190
includes taxes & fees
22 Nov - 23 Nov
Hampton Inn Sikeston
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top New Madrid County Hotel Reviews

Hampton Inn Sikeston

Hampton Inn Sikeston

10/10 Excellent
"I loved the clean room and my husband was so happy about the continental breakfast. He said we’re definitely staying at a Hampton Inn when available."
Sam 1-night trip
Posted 1 day ago
Hampton Inn Sikeston

Explore a world of travel with Expedia