Florence County Accommodation: Find the Best Hotels in Florence County |

Skip to main content

Stays
Flights
Cars
Packages
Activities

Deals
Groups & meetings

Open app
List your property
Support
Trips
Unlock instant savings with Member Prices
- Sign in
- Feedback

Florence County
South Carolina
United States of America
Hotels
Expedia.co.nz

Holiday Rentals in Florence County Florence County Car Hire Florence County Holidays

A wooden suspension bridge surrounded by dense green foliage.

A wooden suspension bridge surrounded by dense green foliage.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Top Cities in Florence County

A panoramic view of a historic city with a river, prominent domed buildings, and a bridge.

A sunset over a forested landscape with a river and a parking lot.

A person walking on a rope bridge surrounded by dense forest.

Check prices for these dates

Tonight

25 Aug - 26 Aug

Tomorrow

26 Aug - 27 Aug

This weekend

28 Aug - 30 Aug

Next weekend

4 Sept - 6 Sept

Filter by

Property class

Property class: 1

Property class: 2

Property class: 3

Property class: 4

Property class: 5

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Good 7+

Very good 8+

Wonderful 9+

Any

Our top choices for Florence County hotels

A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.

A modern hotel with a 'Park Inn by Radisson' sign, featuring a covered entrance, multiple windows, and a parking lot.

A modern living room with a grey sofa, a flat-screen TV, geometric wall art, and a bookshelf with decorative items.

A modern kitchen with a patterned backsplash, wooden cabinets, and stainless steel appliances.

1. Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 star property

Florence

9.0 out of 10, Wonderful, (2,405 reviews)

9.0/10

Wonderful

(2,405 reviews)

"Great place to stay and good location."

"Great place to stay and good location."

United States

Hector

The price is NZ$142

NZ$142

includes taxes & fees

7 Sept - 8 Sept

Park Inn by Radisson Florence, SC

A hotel room with a desk, a bed, a sofa, a TV, and a mirror.

A reception desk with a stone wall backdrop, a sign reading 'Quality Choice Hotels,' and a reception area with a wooden reception desk and two chairs.

A hotel dining area with wooden tables and chairs, a fireplace, and a television.

A hotel room with a fireplace, a flat-screen TV, a sofa, a patterned carpet, and large windows with a view.

2. Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

2.5 star property

Florence

8.4 out of 10, Very good, (340 reviews)

8.4/10

Very good

(340 reviews)

"Friendly staff, clean rooms, great location for traveling through the area and breakfast included."

"Friendly staff, clean rooms, great location for traveling through the area and breakfast included."

United States

Barbara

The price is NZ$165

NZ$165

includes taxes & fees

26 Aug - 27 Aug

Quality Inn & Suites Florence Civic Center

A spacious lobby with a checkered floor, a reception desk, and a chandelier.

A vending area with snack and drink options, including Pepsi refrigerators and a 'MARKET' display with various products.

A two-story building with a brick facade, a flat roof, and a covered entrance area.

A hotel room with two beds, a desk with a computer, a chair, and a bathroom with a mirror.

3. Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2.0 star property

Florence

8.6 out of 10, Excellent, (2,711 reviews)

8.6/10

Excellent

(2,711 reviews)

"Amazing stay!"

"Amazing stay!"

United States

Miriam

The price is NZ$120

NZ$120

includes taxes & fees

13 Sept - 14 Sept

Howard Johnson by Wyndham Florence

A modern lobby with a stone column, a fireplace, and yellow rocking chairs around a central table.

A Country Inn & Suites by Radisson building with a parking lot and palm trees.

An outdoor patio with a wooden table and wicker chairs, a barbecue grill, and a swimming pool in the background.

A modern cafeteria with long wooden tables, green chairs, and yellow accents.

4. Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

2.5 star property

Florence

8.2 out of 10, Very good, (272 reviews)

8.2/10

Very good

(272 reviews)

"property was overall ok what i like the most was that the hotel was steps away from the beach amd an icecream shop right across the street from the hotel"

"property was overall ok what i like the most was that the hotel was steps away from the beach amd an icecream shop right across the street from the hotel"

United States

Francisco

The price is NZ$175

NZ$175

includes taxes & fees

31 Aug - 1 Sept

Spark by Hilton Florence North I-95, SC

A hotel lobby with a reception desk, seating area, and a television screen.

A hotel room with a bed, a sofa, an ottoman, and a lamp.

A spacious dining area with multiple tables and chairs, large windows, and a flat-screen TV mounted on the wall.

A hotel room with a sectional sofa, two ottomans, a bed with a green bedspread, and framed pictures on the wall.

5. Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 star property

Florence

9.0 out of 10, Wonderful, (1,355 reviews)

9.0/10

Wonderful

(1,355 reviews)

"Clean rooms and friendly staff"

"Clean rooms and friendly staff"

United States

Mike

The price is NZ$200

NZ$200

includes taxes & fees

20 Sept - 21 Sept

Comfort Inn & Suites Florence Center Area

A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.

A modern bar area with a long counter, multiple bar stools, and a variety of bottles and glasses.

A multi-story hotel with a modern facade, featuring a prominent 'Hyatt Place' sign on the right.

A modern bar area with a long counter, bar stools, and a variety of bottles and glasses.

6. Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

3.0 star property

Florence

9.0 out of 10, Wonderful, (1,019 reviews)

9.0/10

Wonderful

(1,019 reviews)

"So nice and clean and the bartender - cook was amazing"

"So nice and clean and the bartender - cook was amazing"

United States

April

The price is NZ$214

NZ$214

includes taxes & fees

16 Sept - 17 Sept

Hyatt Place Florence Downtown

An outdoor patio area with tables and chairs, a brick wall, and a glass door leading to the interior.

A spacious living room with hardwood flooring, a staircase, and a large window.

A spacious dining area with multiple tables and chairs, wooden flooring, and a modern chandelier.

A spacious bar area with a wooden floor, multiple bar stools, and a variety of bottles on shelves.

7. The Inn at the Crossroads

The Inn at the Crossroads

2.0 star property

Lake City

9.4 out of 10, Exceptional, (943 reviews)

9.4/10

Exceptional

(943 reviews)

"Very nice and beautifully furnished inn. We enjoyed our stay."

"Very nice and beautifully furnished inn. We enjoyed our stay."

United States

Deborah

The price is NZ$185

NZ$185

includes taxes & fees

26 Aug - 27 Aug

The Inn at the Crossroads

A hotel room with two beds, a wooden headboard, a window with curtains, and a wall-mounted air conditioner.

An indoor swimming pool with clear blue water, surrounded by green chairs and a tiled floor.

A modern kitchen with a built-in coffee station, a refrigerator, and a seating area with a patterned rug.

8. SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence

3.0 star property

Florence

8.4 out of 10, Very good, (1,021 reviews)

8.4/10

Very good

(1,021 reviews)

"Clean room- breakfast was great- staff very helpful"

"Clean room- breakfast was great- staff very helpful"

United States

Florence

The price is NZ$198

NZ$198

includes taxes & fees

30 Aug - 31 Aug

SpringHill Suites by Marriott Florence

A hotel room with two beds, a wooden headboard, a nightstand, and three sunset paintings on the wall.

A modern hotel room with a large bed, two armchairs, a desk with a computer, and a decorative wall.

A lobby with a reception desk, seating area, and artwork on the walls.

A modern kitchen with a central island, a dining area with chairs, a large window with a view of palm trees, and a flat-screen TV mounted on the wall.

9. Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center

2.5 star property

Florence

7.2 out of 10, Good, (1,013 reviews)

7.2/10

Good

(1,013 reviews)

"Pet friendly"

"Pet friendly"

United States

Nelson

The price is NZ$120

NZ$120

includes taxes & fees

16 Sept - 17 Sept

Days Inn by Wyndham Florence Near Civic Center

A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.

A hotel room with two beds, a desk, a TV, and a window with patterned curtains.

A Hampton Inn & Suites with a large sign, brick facade, and a parking lot.

A lobby with a fireplace, seating area, and a television.

10. Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center

2.5 star property

Florence

9.0 out of 10, Wonderful, (953 reviews)

9.0/10

Wonderful

(953 reviews)

"Nice staff, clean establishment, and great breakfast!"

"Nice staff, clean establishment, and great breakfast!"

United States

Jennifer

The price is NZ$206

NZ$206

includes taxes & fees

20 Sept - 21 Sept

Hampton Inn & Suites Florence Center

A hotel entrance with a distinctive arched roof and a brick pathway leading to the doors.

A spacious lobby with a patterned carpet, modern lighting fixtures, and a reception desk.

A spacious lobby with a stone fireplace, modern lighting, and a large plant.

A fire pit surrounded by wicker chairs, a wooden bench, and a staircase leading to an entrance.

11. Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG

3.0 star property

Florence

9.4 out of 10, Exceptional, (1,010 reviews)

9.4/10

Exceptional

(1,010 reviews)

"Out stay was comfortable."

"Out stay was comfortable."

United States

Frederick

The price is NZ$246

NZ$246

includes taxes & fees

13 Sept - 14 Sept

Staybridge Suites Florence - Civic Center by IHG

A spacious lobby with a high ceiling, a central seating area, and a staircase leading to an upper level.

A hotel room with a bed, a sofa, a desk, and a TV.

A hotel room with a bed, sofa, TV, and a desk.

A modern breakfast area with a buffet setup, including a microwave, coffee maker, and various food items.

12. La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence

3.0 star property

Florence

7.8 out of 10, Good, (1,545 reviews)

7.8/10

Good

(1,545 reviews)

"Very convenient location Friendly and helpful staff"

"Very convenient location Friendly and helpful staff"

United States

Heather

The price is NZ$167

NZ$167

includes taxes & fees

30 Aug - 31 Aug

La Quinta Inn & Suites by Wyndham Florence

An indoor swimming pool with clear water, surrounded by lounge chairs and tables, and a sign indicating no lifeguard on duty.

A hotel room with a large bed, a desk with a chair, a television, and a walk-in closet.

A modern breakfast bar with a coffee machine, cereal and fruit options, and a yogurt dispenser.

A hotel entrance with a covered driveway, large columns, and a number "3440" sign.

13. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

2.5 star property

Florence

9.2 out of 10, Wonderful, (1,008 reviews)

9.2/10

Wonderful

(1,008 reviews)

"Wonderful hotel and in a great location!"

"Wonderful hotel and in a great location!"

United States

Leigh

The price is NZ$214

NZ$214

includes taxes & fees

20 Sept - 21 Sept

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

A modern lobby with seating areas, a reception desk, and a large wall with a decorative panel.

A hotel room with a bed, a blue sofa, a brown ottoman, a black office chair, a desk, a lamp, and three framed pictures on the wall.

A modern coffee station with a counter, coffee machines, and a seating area with chairs.

A Comfort Suites hotel with a modern design, featuring a prominent entrance with columns, a covered walkway, and a clear blue sky.

14. Comfort Suites Florence I-95

Comfort Suites Florence I-95

2.5 star property

Florence

8.2 out of 10, Very good, (1,007 reviews)

8.2/10

Very good

(1,007 reviews)

"Great area and nice hotel!"

"Great area and nice hotel!"

United States

Jennifer

The price is NZ$170

NZ$170

includes taxes & fees

14 Sept - 15 Sept

Comfort Suites Florence I-95

A hotel room with a bed, bedside table with a phone, a desk with a chair, a TV mounted on the wall, and a window with curtains.

A multi-story hotel with a prominent entrance marked '1912'.

A reception area with a wooden counter, a seating area with tables and chairs, and a large window with a view.

A modern kitchen with dark wood cabinets, stainless steel appliances, and a large juice dispenser.

15. Microtel Inn & Suites by Wyndham Florence

Microtel Inn & Suites by Wyndham Florence

2.0 star property

Florence

7.0 out of 10, Good, (1,011 reviews)

7.0/10

Good

(1,011 reviews)

"I enjoyed my stays"

"I enjoyed my stays"

United States

Carletta

The price is NZ$101

NZ$101

includes taxes & fees

30 Aug - 31 Aug

Microtel Inn & Suites by Wyndham Florence

A swimming pool with lounge chairs and a building with a sign reading "BAYMONT".

A motel with a covered parking area, a gas station sign, and a row of rooms with balconies.

A hotel room with a large bed, a desk, a chair, a TV, and a painting of a waterfall on the wall.

A bathroom with a sink, mirror, towel rack, and a towel hanging on the wall.

16. Super 8 by Wyndham Florence

Super 8 by Wyndham Florence

2.0 star property

Florence

7.2 out of 10, Good, (1,023 reviews)

7.2/10

Good

(1,023 reviews)

"Wonderful tv could be a lil bigger or updated but otherwise good stay"

"Wonderful tv could be a lil bigger or updated but otherwise good stay"

United States

Darius

The price is NZ$97

NZ$97

includes taxes & fees

26 Aug - 27 Aug

Super 8 by Wyndham Florence

A Courtyard by Marriott hotel with a covered entrance, multiple floors, and a parking lot.

An indoor swimming pool with clear water, surrounded by tiled walls and a wooden floor. There are chairs and a table near the pool, and large windows allow natural light to enter.

A hotel room with two beds, a desk, a chair, and a TV.

A modern bar area with a counter, stools, and tables.

17. Courtyard by Marriott Florence

Courtyard by Marriott Florence

3.0 star property

Florence

7.8 out of 10, Good, (766 reviews)

7.8/10

Good

(766 reviews)

"We enjoyed our stay very much the staff were very helpful and friendly from the beginning to the end! Parking was great! My only problem would be that breakfast is not included in the stay but overall this was a really good stay for my mother and I. I would definitely book with them again"

"We enjoyed our stay very much the staff were very helpful and friendly from the beginning to the end! Parking was great! My only problem would be that breakfast is not included in the stay but overall this was a really good stay for my mother and I. I would definitely book with them again"

United States

Ziporah

The price is NZ$199

NZ$199

includes taxes & fees

13 Sept - 14 Sept

Courtyard by Marriott Florence

A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.

A modern kitchen with a coffee station, a dining area with a table and chairs, and a living area with a sofa and a coffee table.

A modern lounge area with a sofa, armchairs, and small tables.

A reception area with a wooden desk, a map on the wall, and a sign welcoming visitors to Florence, SC.

18. TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence

3.0 star property

Florence

9.0 out of 10, Wonderful, (882 reviews)

9.0/10

Wonderful

(882 reviews)

"Always a good stay"

"Always a good stay"

United Kingdom

William

The price is NZ$213

NZ$213

includes taxes & fees

30 Aug - 31 Aug

TownePlace Suites by Marriott Florence

A Holiday Inn Express & Suites building with a symmetrical facade, large windows, and a central entrance with a canopy.

A reception desk with two computer monitors, a lamp, framed artwork, and a window in the background.

An indoor swimming pool with clear views of the outdoors, surrounded by lounge chairs and a lifeguard stand.

A hotel reception area with a modern design, featuring a reception desk, seating area, and a large artwork on the wall.

19. Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

2.5 star property

Florence

8.6 out of 10, Excellent, (1,013 reviews)

8.6/10

Excellent

(1,013 reviews)

"Great stay. Clean room, great breakfast"

"Great stay. Clean room, great breakfast"

United States

Tim

The price is NZ$253

NZ$253

includes taxes & fees

22 Sept - 23 Sept

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

A spacious room with a large window, a coffee machine, two chairs, and a potted plant.

A modern office entrance with a glass door, a pull handle, and a "PULL" sign.

A covered walkway with steps leading to a building.

A hotel room with a large bed, a nightstand, a wall-mounted light, a painting, and a separate bathroom with a bathtub.

20. Florence Inn and Suites

Florence Inn and Suites

2.5 star property

Florence

6.6 out of 10, (395 reviews)

6.6/10

(395 reviews)

"Nice hotel for a great price "

"Nice hotel for a great price "

United States

Payton

The price is NZ$103

NZ$103

includes taxes & fees

30 Aug - 31 Aug

Florence Inn and Suites

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Sign up, it's free

Top Florence County Hotel Reviews

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

10/10 Excellent

"I frequent this hotel ALOT...as this is my home away from home. I love the staff! I have no complaints. No other hotel to me can COMPETE because they don't COMPARE!"

Imani 2-night trip

Posted 13 hours ago

Comfort Inn & Suites Florence Center Area

Microtel Inn & Suites by Wyndham Florence

Microtel Inn & Suites by Wyndham Florence

8/10 Good

"Was not a fan of the hundred dollar deposit. Did not have a hot breakfast and wasn’t able to hook a HDMI cord to my TV."

Roneisha 1-night trip

Posted 2 days ago

Microtel Inn & Suites by Wyndham Florence

Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center

8/10 Good

"The room is spacious but has no view. The curtain cannot be fully closed . The breakfast is good with fried egg and boiled egg, plus yogurt and berries and other fruits."

Jing 1-night trip

Posted 2 days ago

Hampton Inn & Suites Florence Center

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

8/10 Good

"Easy parking - pleasant staff."

Bryan 1-night trip

Posted 2 days ago

Howard Johnson by Wyndham Florence

The Inn at the Crossroads

The Inn at the Crossroads

10/10 Excellent

"Such details! Beautiful art everywhere! Hidden gem!"

Arlene 1-night trip

Posted 3 days ago

The Inn at the Crossroads

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

10/10 Excellent

"Wonderful hotel and in a great location!"

Leigh 1-night trip

Posted 3 days ago

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence

10/10 Excellent

"I liked the pool and pool towels. One issue is that I'm short 4 ' 10 and old. So when the microwave is over my head and 7 feet up. I can't really use it . Next time think of us little people. Otherwise I have been using Marriott for over 30 years and it's my favorite."

Bonnie 1-night trip

Posted 3 days ago

SpringHill Suites by Marriott Florence

TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence

10/10 Excellent

"Always a good stay"

William 1-night trip

Posted 6 days ago

TownePlace Suites by Marriott Florence

Explore a world of travel with Expedia

Lodging
Flights
Packages
Cars
Holiday Rentals
Other
Explore a world of travel with Expedia

Flights from Manchester (MAN) to Florence (FLO)
Flights from Christchurch (CHC) to Florence (FLO)
Flights from Auckland (AKL) to Florence (FLO)
Flights from San Diego (SAN) to Andrews (ADR)
Flights from Amsterdam (AMS) to Andrews (ADR)
Flights from Boston (BOS) to Andrews (ADR)
Flights from Concord (USA) to Cheraw (HCW)
Flights from Florence Regional
Flights from Shaw Air Force Base
Flights from Cheraw
Flights to Florence
Flights from Lamar
Flights from Salters
Flights from Camden
Flights from Hamer

Visit Socastee
Visit Dalzell
Visit Cades
Visit Salters
Visit Olanta
Visit Turbeville
St. Stephen's Episcopal Church
Conway Riverwalk
Palmetto Tennis Center
Hamer Holidays
Shaftesbury Glen Golf and Fish Club
Florence Holidays

Car hire Horatio
Car hire Florence
Car hire Pageland
Rental cars Florence Regional airport
Car hire Gable
Car hire Hamer
Car hire Darlington
Car hire near The Wizard
Hertz Rental Cars in Florence
Budget Rental Cars in Sumter

Johnsonville Holiday Rentals
Cheraw Holiday Rentals

Activities in Socastee

Book Hotels in Florence County on Expedia.com

Go further with the Expedia app

Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go.

Scan the QR code with your device camera and download our app

QR code to download the app

Company

About us
Jobs
List your property
Partnerships
Newsroom

Explore

New Zealand travel guide
Hotels in New Zealand
Holiday rentals in New Zealand
Holiday packages in New Zealand
Domestic flights
Car rentals in New Zealand
All accommodation types
Travel blog
Rewards with One Key

Policies

Privacy
Cookies
Terms of use
One Key™ terms and conditions
Bookabach terms and conditions
Legal information / Contact us
Content guidelines and reporting content

Help

Support
Change or cancel your booking
Refund process and timelines
Book a flight using an airline credit
International travel documents

© 2026 Expedia, Inc., an Expedia Group company. All rights reserved. Expedia and the Expedia Logo are trademarks or registered trademarks of Expedia, Inc.

63a81855-e8c0-4d92-bd8e-09cf10f72d11420b8d07-b133-4b84-982e-0e5804e61886