Search Florence hotels

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Florence hotels

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
2.5 star property
Florence
9.0 out of 10, Wonderful, (2196)
"Breakfast was great, room very clean ."
United States
Leann
The price is NZ$164
includes taxes & fees
23 Dec - 24 Dec
Park Inn by Radisson Florence, SC

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
2.5 star property
Florence
9.2 out of 10, Wonderful, (1169)
"Enjoyed our stay there. "
United States
Cathy
The price is NZ$191
includes taxes & fees
28 Dec - 29 Dec
Comfort Inn & Suites Florence Center Area

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
2.0 star property
Florence
8.6 out of 10, Excellent, (2490)
"I nice place to stay, very quiet, good breakfast, nice staff, spotless room. "
United States
Timothy
The price is NZ$120
includes taxes & fees
22 Dec - 23 Dec
Howard Johnson by Wyndham Florence

Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
3.0 star property
Florence
8.8 out of 10, Excellent, (1007)
"Great stay"
United States
Michaelle
The price is NZ$194
includes taxes & fees
5 Jan - 6 Jan 2026
Hyatt Place Florence Downtown

Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
2.5 star property
Florence
8.4 out of 10, Very good, (1006)
"Hotel was clean , friendly staff"
United States
Gabriela
The price is NZ$187
includes taxes & fees
1 Jan - 2 Jan 2026
Tru by Hilton Florence I-95

Holiday Inn Express & Suites Latta by IHG

Holiday Inn Express & Suites Latta by IHG
2.5 star property
Latta
9.4 out of 10, Exceptional, (532)
"Clean and beautiful, very friendly staff "
United States
claudia
The price is NZ$211
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express & Suites Latta by IHG

Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC
2.5 star property
Florence
8.0 out of 10, Very good, (25)
"Friendly staff and clean environment "
United States
john
The price is NZ$188
includes taxes & fees
28 Dec - 29 Dec
Spark by Hilton Florence North I-95, SC

Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
2.5 star property
Florence
9.0 out of 10, Wonderful, (814)
"The hotel was excellent. In fact we stayed 2 different nights on our travel up and down Rt 95. Breakfast was great and hotel very clean and quiet. "
United States
Cynthia
The price is NZ$221
includes taxes & fees
31 Dec - 1 Jan 2026
Hampton Inn & Suites Florence-North-I-95

Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
2.5 star property
Florence
9.0 out of 10, Wonderful, (553)
"Clean room, professional and courteous staff. "
United States
Felicia
The price is NZ$200
includes taxes & fees
21 Dec - 22 Dec
Fairfield Inn & Suites by Marriott Florence I-20

Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
2.5 star property
Florence
7.8 out of 10, Good, (1252)
"Newly remodeled rooms. Very clean. Very friendly staff "
United States
Theresa
The price is NZ$156
includes taxes & fees
24 Dec - 25 Dec
Quality Inn & Suites Florence Civic Center

Residence Inn Marriott Florence

Residence Inn Marriott Florence
3.0 star property
Florence
8.8 out of 10, Excellent, (478)
"Yes our stay was great big variety on breakfast clean hotel rooms nice to have a kitchen had a great day"
United States
Marialinda
The price is NZ$184
includes taxes & fees
28 Dec - 29 Dec
Residence Inn Marriott Florence

Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
3.0 star property
Florence
9.4 out of 10, Exceptional, (926)
"Friendly staff, great breakfast, beautiful ammenities!"
United States
Brandi
The price is NZ$242
includes taxes & fees
11 Jan - 12 Jan 2026
Staybridge Suites Florence - Civic Center by IHG

Best Western Inn

Best Western Inn
2.5 star property
Florence
7.6 out of 10, Good, (1002)
"Spotless room and courteous staff"
United States
Krusaundra
The price is NZ$172
includes taxes & fees
28 Dec - 29 Dec
Best Western Inn

La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence
3.0 star property
Florence
8.0 out of 10, Very good, (1675)
"Th room was nice comfortable breakfast was good and the people were very friendly "
United States
George
The price is NZ$173
includes taxes & fees
24 Dec - 25 Dec
La Quinta Inn & Suites by Wyndham Florence

Super 8 by Wyndham Florence

Super 8 by Wyndham Florence
2.0 star property
Florence
7.0 out of 10, Good, (1004)
"Clean room, Courteous Staff."
United States
Rhodney
The price is NZ$102
includes taxes & fees
25 Dec - 26 Dec
Super 8 by Wyndham Florence

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
2.5 star property
Florence
8.6 out of 10, Excellent, (1006)
"Room was clean, staff was courteous and breakfast was great !"
United States
Angela
The price is NZ$221
includes taxes & fees
21 Dec - 22 Dec
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Homewood Suites by Hilton Florence

Homewood Suites by Hilton Florence
3.0 star property
Florence
8.4 out of 10, Very good, (657)
"The staff was amazing and the hotel is pretty fresh in terms of amenities "
United States
Shahid
The price is NZ$196
includes taxes & fees
4 Jan - 5 Jan 2026
Homewood Suites by Hilton Florence

Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
2.5 star property
Florence
9.0 out of 10, Wonderful, (819)
"My go to stay while in Fairfax. "
United States
Gregory
The price is NZ$189
includes taxes & fees
11 Jan - 12 Jan 2026
Hampton Inn & Suites Florence Center

Fairfield Inn by Marriott Hartsville

Fairfield Inn by Marriott Hartsville
2.5 star property
Hartsville
8.6 out of 10, Excellent, (678)
"very friendly older property but clean"
United States
Tamiko
The price is NZ$179
includes taxes & fees
26 Dec - 27 Dec
Fairfield Inn by Marriott Hartsville

TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
3.0 star property
Florence
9.0 out of 10, Wonderful, (702)
"Good stay, great staff"
United States
James
The price is NZ$192
includes taxes & fees
28 Dec - 29 Dec
TownePlace Suites by Marriott Florence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Florence attractions

Florence and related destinations

Stroll through the West Broad Street Historic District to soak up local history before exploring the Florence Museum's diverse exhibits. Catch a show at the Florence Civic Centre or hunt for bargains at Magnolia Mall for a taste of modern entertainment.

Wyche Pavilion Greenville South Carolina

Top Florence Hotel Reviews

More cheap accommodation in Florence

Frequently asked questions

What's the best place to stay in Florence?
Staybridge Suites Florence - Civic Center by IHG is ranked highly by Expedia customers. This hotel offers free breakfast and a restaurant. Reviews from our site also recommend Fairfield Inn & Suites by Marriott Florence I-20 and Comfort Inn & Suites Florence Center Area as top options for your stay. See all available top hotels, or vacation rentals in Florence.
What are some of the best holiday rentals that Florence has to offer?
Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's: This highly rated holiday home rental in Florence offers a fireplace, a patio and air conditioning to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. Make the most of garden in this rental home to help you unwind. Some other top choices in Florence are Perfect Stop • Near I-95, Downtown & Civic Center and Darlington and Pineapple House: Historic. Southern Charm. Walk Downtown.. See all vacation rentals in Florence.
If I need to cancel my hotel reservation in Florence, will I receive a refund?
Yes, the majority of room reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Florence.
What's the best accommodation for a budget-friendly stay in Florence?
Based on reviews, Park Inn by Radisson Florence, SC is a popular hotel for our travellers who want a more economical choice, and features free buffet breakfast and free Wi-Fi. Other good choices to stay on the cheap include La Quinta Inn & Suites by Wyndham Florence and Howard Johnson by Wyndham Florence. View all budget hotels in Florence.
What's the best family accommodation in Florence?
La Quinta Inn & Suites by Wyndham Florence is a hotel with free parking and free breakfast, and it's a top choice on Expedia for families. Other choices to stay with the children include Howard Johnson by Wyndham Florence and Aloft Florence. Find more child-friendly accommodations in Florence.
What is the top LGBTQ-friendly place to stay in Florence?
TownePlace Suites by Marriott Florence is a top LGBTQ-friendly hotel that features free breakfast and free parking. Tru by Hilton Florence I-95 and Courtyard by Marriott Florence are two other good options for your stay. See all available hotels listed as LGBTQ-friendly in Florence.
What's the best dog-friendly place to stay in Florence?
Park Inn by Radisson Florence, SC is a top hotel for people travelling with their pets, and offers a 24-hour fitness centre and free WiFi for its human guests. Other good options for you and your pet's trip include Comfort Inn & Suites Florence Center Area and La Quinta Inn & Suites by Wyndham Florence. See more pet-friendly hotel accommodations in Florence.
What are some accommodation options with pools in Florence?
Hyatt Place Florence Downtown is a top hotel with an outdoor pool, free breakfast and free WiFi. A couple of other options that feature an on-site pool include Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG and Homewood Suites by Hilton Florence. View all hotels with pools in Florence.
What is the best spa hotel in Florence?
Hotel Florence, Tapestry Collection by Hilton is a top spa hotel featuring a 24-hour fitness centre, a bar and a restaurant. Enjoy a facial, detox wrap or Swedish massage at the on-site spa. See all spa hotels in Florence.
What is staying in Florence like?
Families will find child-friendly activities in Florence, and visitors give high marks for the top-notch restaurants and shopping. This welcoming city also attracts tourists with its entertainment. In Florence, there are 108 hotels and other accommodation options to choose from. Find out more about Florence.
What are the top places to visit in Florence?
Landmarks like Mcleod Regional Medical Center, Florence National Cemetery and Florence Veterans Park might be worth a visit. A couple of additional sights to add to your itinerary are Florence Museum and Dr. Eddie Floyd Tennis Center. Take a look at what more there is to see and do in Expedia's Florence guide.
How can I get around Florence?
If you want to explore the larger area, take a train from Florence Station. If you want to venture out around the area, you may want a rental car in Florence for your journey.
What's the weather like in Florence?
The hottest months are usually July and August, with an average temperature of 26°C, while the coldest months are January and February, with an average of 10°C. Average annual precipitation for Florence is 1366 mm.

Explore a world of travel with Expedia