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Central San Mateo Hotels, San Francisco

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Our top choices for Central San Mateo hotels

Holiday Inn Hotel & Suites San Mateo-San Francisco SFO by IHG

Holiday Inn Hotel & Suites San Mateo-San Francisco SFO by IHG
3.0 star property
Central San Mateo
7.8 out of 10, Good, (1009)
"Yes, room was clean, staff very kind. "
United States
Jesus
The price is NZ$194
includes taxes & fees
23 Jan - 24 Jan 2026
Holiday Inn Hotel & Suites San Mateo-San Francisco SFO by IHG

Sanmateo Cozy Central 3b1b Home Garage Parking AC

Sanmateo Cozy Central 3b1b Home Garage Parking AC
2.0 star property
Central San Mateo
The price is NZ$872
includes taxes & fees
4 Jan - 5 Jan 2026
Sanmateo Cozy Central 3b1b Home Garage Parking AC

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf
4.0 star property
28.2 km from Central San Mateo
9.0 out of 10, Wonderful, (7209)
"Great place to stay!"
United States
Isaiah
The price is NZ$287
includes taxes & fees
5 Jan - 6 Jan 2026
Hotel Riu Plaza Fisherman's Wharf

Hotel Caza Fisherman's Wharf

Hotel Caza Fisherman's Wharf
4.0 star property
28.3 km from Central San Mateo
9.0 out of 10, Wonderful, (3843)
"Excellent stay and great location! "
United States
CHRISTINE
The price is NZ$326
includes taxes & fees
22 Jan - 23 Jan 2026
Hotel Caza Fisherman's Wharf

Hilton San Francisco Airport Bayfront

Hilton San Francisco Airport Bayfront
4.0 star property
3.4 km from Central San Mateo
8.6 out of 10, Excellent, (2750)
"Nice airport hotel…staff was great, breakfast was amazing "
United States
Lynne
The price is NZ$183
includes taxes & fees
3 Jan - 4 Jan 2026
Hilton San Francisco Airport Bayfront

Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco
4.0 star property
26.6 km from Central San Mateo
8.8 out of 10, Excellent, (2821)
"Clean room, friendly staff and good location"
United States
Jose Eduardo
The price is NZ$183
includes taxes & fees
25 Dec - 26 Dec
Club Quarters Hotel in San Francisco

Hilton San Francisco Financial District

Hilton San Francisco Financial District
4.0 star property
26.7 km from Central San Mateo
8.6 out of 10, Excellent, (2168)
"Great hotel "
United States
Tanya
The price is NZ$221
includes taxes & fees
4 Jan - 5 Jan 2026
Hilton San Francisco Financial District

The Westin San Francisco Airport

The Westin San Francisco Airport
4.0 star property
6.4 km from Central San Mateo
8.8 out of 10, Excellent, (2029)
"Comfortable room, welcome glass of wine, easy shuttle to and from airport, friendly staff."
United States
Carole
The price is NZ$253
includes taxes & fees
26 Dec - 27 Dec
The Westin San Francisco Airport

Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG
3.5 star property
26.6 km from Central San Mateo
9.0 out of 10, Wonderful, (5026)
"Rooms were great, staff was great, location was great. "
United States
Jonathan
The price is NZ$226
includes taxes & fees
5 Jan - 6 Jan 2026
Holiday Inn Golden Gateway by IHG

Chancellor Hotel on Union Square

Chancellor Hotel on Union Square
3.5 star property
26.1 km from Central San Mateo
9.4 out of 10, Exceptional, (3086)
"Great hotel, great location, super friendly all staff "
Mexico
Claudia
The price is NZ$153
includes taxes & fees
4 Jan - 5 Jan 2026
Chancellor Hotel on Union Square

Hotel Zephyr San Francisco

Hotel Zephyr San Francisco
4.0 star property
28.3 km from Central San Mateo
8.6 out of 10, Excellent, (2341)
"Great decor and really great location"
United States
Jose
The price is NZ$315
includes taxes & fees
8 Jan - 9 Jan 2026
Hotel Zephyr San Francisco

King George Hotel

King George Hotel
3.0 star property
25.9 km from Central San Mateo
8.6 out of 10, Excellent, (2101)
"Great place!"
United States
Troy
The price is NZ$198
includes taxes & fees
8 Jan - 9 Jan 2026
King George Hotel

Handlery Union Square Hotel

Handlery Union Square Hotel
3.5 star property
26 km from Central San Mateo
8.8 out of 10, Excellent, (2799)
"Clean hotel, great location, kind staff! "
United States
Felix
The price is NZ$256
includes taxes & fees
25 Dec - 26 Dec
Handlery Union Square Hotel

Holiday Inn Express and Suites Fisherman's Wharf by IHG

Holiday Inn Express and Suites Fisherman's Wharf by IHG
3.0 star property
28.2 km from Central San Mateo
9.0 out of 10, Wonderful, (2233)
"Hotel is so nice, the room is so clean, the staff is so nice."
United States
Griselda
The price is NZ$272
includes taxes & fees
25 Dec - 26 Dec
Holiday Inn Express and Suites Fisherman's Wharf by IHG

Hotel Zoe Fisherman's Wharf

Hotel Zoe Fisherman's Wharf
4.0 star property
28.2 km from Central San Mateo
9.2 out of 10, Wonderful, (1631)
"Great location, service, and rooms!"
United States
Joyce
The price is NZ$294
includes taxes & fees
6 Jan - 7 Jan 2026
Hotel Zoe Fisherman's Wharf

DoubleTree by Hilton San Francisco Airport

DoubleTree by Hilton San Francisco Airport
4.0 star property
3.8 km from Central San Mateo
8.6 out of 10, Excellent, (1378)
"Great location and staff"
United States
Ernest Dean
The price is NZ$206
includes taxes & fees
28 Dec - 29 Dec
DoubleTree by Hilton San Francisco Airport

Aloft San Francisco Airport

Aloft San Francisco Airport
3.0 star property
6.4 km from Central San Mateo
9.0 out of 10, Wonderful, (2233)
"All good, friendly staff, spotless room. "
United States
Michael
The price is NZ$204
includes taxes & fees
29 Dec - 30 Dec
Aloft San Francisco Airport

Hyatt Centric Fisherman's Wharf San Francisco

Hyatt Centric Fisherman's Wharf San Francisco
4.0 star property
28.2 km from Central San Mateo
8.6 out of 10, Excellent, (1474)
"Not so special but nice place to stay "
United States
Claire
The price is NZ$342
includes taxes & fees
2 Jan - 3 Jan 2026
Hyatt Centric Fisherman's Wharf San Francisco

Hotel Nikko San Francisco

Hotel Nikko San Francisco
4.5 star property
25.8 km from Central San Mateo
9.4 out of 10, Exceptional, (2653)
"Great service, great location, great hotel. "
United States
Laura
The price is NZ$385
includes taxes & fees
4 Jan - 5 Jan 2026
Hotel Nikko San Francisco

Comfort Inn by the Bay

Comfort Inn by the Bay
2.5 star property
27.9 km from Central San Mateo
8.4 out of 10, Very good, (1229)
"Clean room, extremely helpful staff, well located"
Canada
Tammy
The price is NZ$218
includes taxes & fees
4 Jan - 5 Jan 2026
Comfort Inn by the Bay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our guide on where to stay in Central San Mateo

Find the best Central San Mateo areas for the activities you enjoy most.

Union Square

Fashion puts its best foot forward in one of America’s largest shopping plazas.

Downtown San Francisco

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and Chase Center are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

Fisherman's Wharf

Taste some of the city’s freshest sea food and catch some fabulous views in this waterfront neighbourhood dating back to the time of the gold rush.

South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

Nob Hill

Examine architecturally significant buildings, visit the Cable Car Museum and enjoy magnificent views of greater San Francisco in this affluent district.

Top Central San Mateo Hotel Reviews

Frequently asked questions

What is Central San Mateo like?
You'll be sure to have fun exploring San Mateo's Central San Mateo neighbourhood. Are you looking for Central San Mateo travel tips? Make sure that you visit The San Mateo Japanese Garden and Cinemark Century San Mateo 12 while you're in the neighbourhood.
What's a favourite place to stay in Central San Mateo?
Based on Expedia customer reviews, Holiday Inn Hotel & Suites San Mateo-San Francisco SFO by IHG is the highest ranked property in Central San Mateo. This hotel offers a restaurant and a 24-hour fitness centre.
How many hotels will I find in the Central San Mateo area?
Expedia has 45 hotels and other accommodation options in Central San Mateo to choose from, making this an ideal home base for exploring the greater San Mateo area.
If I need to cancel my hotel reservation in Central San Mateo, will I receive a refund?
Yes! The majority of room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within 24 hours of booking. Put your dates in and click on "Search", then use the "fully refundable" filter to get the best deals in Central San Mateo.
What is there to do in this San Mateo neighbourhood?
A few attractions you might want to check out while you're in Central San Mateo are The San Mateo Japanese Garden and Cinemark Century San Mateo 12. While you're out sightseeing, Burlingame Museum of PEZ Memorabilia and Poplar Creek Golf Course are a couple of additional sights to visit in San Mateo.
How can I get around Central San Mateo and the greater San Mateo area?
If you want to venture out of town, San Mateo Station is the closest train station. You can also catch a ride at Hayward Park Station.