Photo by Southernmost Illinois Tourism Bureau

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Top Pet-friendly Southern Illinois Hotels

La Quinta Inn & Suites by Wyndham Effingham

1103 Avenue Of Mid America Effingham IL

4 hours drive from Shawnee National Forest

Stay at this business-friendly hotel in Effingham. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...

9.2/10 Wonderful! (1,007 reviews)

The room was nicely decorated and they were more than accommodating with towels and blankets and pillows. The pool was clean and big enough for our volleyball team to enjoy together. Unfortunately, there were no cots available for our use.

Reviewed on 7 Feb 2026

La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis

136 Regency Park O'Fallon IL

4 hours drive from Shawnee National Forest

Stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the clean rooms in their reviews. Popular ...

5.8/10 (1,002 reviews)

Nice for price

Reviewed on 4 Feb 2026

Red Roof Inn St Louis - Troy, IL

2030 Formosa Road Troy IL

4 hours drive from Shawnee National Forest

Stay at this business-friendly hotel in Troy. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms in their ...

7.6/10 Good! (1,001 reviews)

Would stay ahain

Reviewed on 18 Jan 2026

See all 1,150 properties in Southern Illinois

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.