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Top Pet-friendly Southeast Missouri Hotels

Motel 6 Poplar Bluff, MO

4101 Highway 67 N Poplar Bluff MO

2 hours drive from Johnson's Shut-ins State Park

Stay at this motel in Poplar Bluff. Enjoy free Wi-Fi, free parking and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in their ...

8/10 Very Good! (1,001 reviews)

"The motel was great, however, they did not have blankets for the beds and the shower head left a lot to be desired. We would stay here again."

Reviewed on 15 June 2026

Microtel Inn & Suites by Wyndham Sainte Genevieve

21958 Hwy 32 Ste Genevieve MO

3 hours drive from Johnson's Shut-ins State Park

Stay at this business-friendly hotel in Ste Genevieve. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms ...

8.8/10 Excellent! (641 reviews)

"I recommend this motel as it is in St. Genevieve making it the primary motel option. It is clean, nice, safe. Could add a little something to the continental breakfast, like breakfast burritos but that is a quibble...McD's is only five minutes away. If you are there to see Ste. Genevieve, or Fort ..."

Reviewed on 19 June 2026

La Quinta Inn & Suites by Wyndham Festus - St. Louis South

1001 Veterans Blvd Festus MO

2 hours drive from Johnson's Shut-ins State Park

Stay at this business-friendly hotel in Festus. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in their ...

8/10 Very Good! (1,003 reviews)

"Not once in my 3 day stay did anyone come in and clean the room."

Reviewed on 19 June 2026

See all 661 properties in Southeast Missouri

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.