Northeast Mississippi Luxury Holidays 2026

Photo by Martin Tucker

Plan, book, travel with confidence
Better together
Save up to NZ$2,400 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place

Top Luxury Northeast Mississippi Hotels

Super 8 by Wyndham Oxford MS University Area

2201 Jackson Ave W Oxford MS

5 min drive from University of Mississippi

Stay at this business-friendly hotel in Oxford. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular ...

Spark by Hilton Tupelo

186 Stone Creek Blvd Tupelo MS

2 hours drive from University of Mississippi

Stay at this business-friendly hotel in Tupelo. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms in ...

8.4/10 Very good! (1,001 reviews)

"Very comfortable and clean rooms. Continental breakfast was very nice with a lot of options. The food seemed fresh and hot. Location was excellent for our bike riding on the Natchez Trace."

Reviewed on 30 Sept 2026

Quality Inn Tupelo Central

1190 N Gloster St Tupelo MS

2 hours drive from University of Mississippi

Stay at this business-friendly hotel in Tupelo. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular ...

See all 1,571 properties in Northeast Mississippi

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.