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Top Luxury South Carolina Midlands Hotels

The Ballantyne, A Luxury Collection Hotel, Charlotte

10000 Ballantyne Commons Pkwy Charlotte NC

3 hours drive from Fort Jackson

Stay at this luxury hotel in Charlotte. Enjoy free Wi-Fi, 2 indoor pools and a full-service spa. Our guests praise the helpful staff and the property condition ...

9.2/10 Wonderful! (1,001 reviews)

This hotel is always amazing I find it so welcoming and relaxing.

Reviewed on 30 Nov 2025

The Willcox

100 Colleton Avenue SW Aiken SC

2 hours drive from Fort Jackson

Stay at this business-friendly hotel in Aiken. Enjoy free breakfast, free parking and a fitness centre. Popular attractions The Alley and Aiken County Historical ...

9.6/10 Exceptional! (142 reviews)

What an amazing find! The rooms and the staff were amazing our only regret was that we were only staying for the one night. We are already planning an extended stay at the Willcox.

Reviewed on 5 Nov 2025

The Mantissa Hotel

130 East Carolina Ave Hartsville SC

2 hours drive from Fort Jackson

Stay at this hotel in Hartsville. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular attractions ...

9/10 Wonderful! (270 reviews)

Excellent staff and in the heart of a beautiful downtown.

Reviewed on 5 Dec 2025

See all 3,092 properties in South Carolina Midlands

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.