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Top Luxury South Carolina Midlands Hotels

The Ballantyne, A Luxury Collection Hotel, Charlotte

10000 Ballantyne Commons Pkwy Charlotte NC

3 hours drive from Fort Jackson

Stay at this luxury hotel in Charlotte. Enjoy free Wi-Fi, an outdoor pool and a full-service spa. Our guests praise the helpful staff and the property condition ...

9.2/10 Wonderful! (1,001 reviews)

"This hotel is leagues above most large-city hotels, with the possible exceptions of a Four Seasons or Waldorf location. Simply a beautiful place with focus on details like full-marble shower walls, custom-manufactured mattresses, and thoroughly professional staff. We are looking forward to the next ..."

Reviewed on 21 June 2026

The Willcox

100 Colleton Avenue SW Aiken SC

2 hours drive from Fort Jackson

Stay at this business-friendly hotel in Aiken. Enjoy free breakfast, free parking and a fitness centre. Popular attractions The Alley and Aiken County Historical ...

The Mantissa Hotel

130 East Carolina Ave Hartsville SC

2 hours drive from Fort Jackson

Stay at this hotel in Hartsville. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular attractions ...

9.2/10 Wonderful! (292 reviews)

"Most amazing stay! Very location to the heart of hartsville! The suites are apartment style with all of the amenities you could ever need for your stay! The staff is so kind and inviting! Already booked our next stay, can’t wait to come back!"

Reviewed on 15 June 2026

See all 3,280 properties in South Carolina Midlands

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.