Photo by Southernmost Illinois Tourism Bureau

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Top Kid friendly Southwest Illinois Hotels

Country Inn & Suites by Radisson, Marion, IL

1306 Halfway Road Marion IL

43 min drive from Southern Illinois University

Stay at this business-friendly hotel in Marion. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in their ...

8.6/10 Excellent! (1,003 reviews)

Clean and comfortable, close to restaurants.

Reviewed on 4 Mar 2026

Drury Plaza Hotel Mt. Vernon

145 North 44th Street Mount Vernon IL

2 hours drive from Southern Illinois University

Stay at this business-friendly hotel in Mount Vernon. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...

9.6/10 Exceptional! (1,666 reviews)

The Drury Inn is always a pleasant stay. Breathed is always delicious! I always appreciate tte complimentary drinks and food in the evening too.

Reviewed on 9 Mar 2026

Comfort Inn & Suites O'Fallon - St. Louis Area

116 Regency Park O'Fallon IL

3 hours drive from Southern Illinois University

Stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular ...

6.6/10 (115 reviews)

I was surprised at how filthy the room and sheets were. I ended up checking out early and going somewhere else.

Reviewed on 6 Mar 2026

See all 745 properties in Southwest Illinois

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.