Cheap American Airlines Flights from Portland to San Diego (PWM→SAN)

You can discover affordable round-trip American Airlines flights from PWM to SAN by organising your results from "Price (lowest to highest)" on Expedia. Or search for deals for a one-way trip.*

*These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

American Airlines flights to San Diego are typically cheaper in the off-peak months of January and November. Whether you're searching for a return or one-way ticket, you could find a better deal then.

Fill in your dates, click search and check "Nonstop" on Expedia to find any direct flights from PWM to SAN with American Airlines or another carrier.

Jump on an American Airlines flight from Portland Intl. Jetport Airport (PWM) to San Diego, and you'll probably touch down at San Diego Intl. Airport (SAN). This is the airline's main hub in this destination.

Typically, you can cancel or reschedule your flight, although there may be a charge if your booking was made more than 24 hours ago. Need flexible options? Use our "No cancel fee" or "Changes included" filter to find flights that won't penalize you if you need to revise your plans. To make modifications, head to "Trips," select your flight and click on "Manage Booking" for more information.