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The best area to stay in St Charles is the historic Main Street district, which runs parallel to the Missouri River.This area is the heart of St Charles, known for its beautifully preserved brick buildings, gas lamps, and cobblestone streets. Main Street itself is pedestrian-friendly, lined with independent shops, art galleries, and a variety of restaurants. It's a very walkable area, stretching from the First State Capitol Building on the north end to the Lewis & Clark Boat House and Museum towards the south.Couples often find this area great for a relaxing getaway. You can enjoy strolls along the riverfront, explore the numerous unique boutiques, and dine at charming restaurants, many of which offer outdoor seating. The evening entertainment, including live music venues, is also easily accessible.For those interested in history and exploring on foot, staying close to Main Street is ideal. You're within easy reach of historic sites like the Boone's Lick Road and the starting point of the Lewis and Clark expedition.