South Mission Beach Holidays

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Our guide on where to stay in South Mission Beach

Find the best South Mission Beach areas and neighborhoods for the activities you enjoy most. Learn more about South Mission Beach
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Downtown San Diego

3 out of top 10 points of interest in this area
4.5/5(100 area reviews)

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Find hotels in Downtown San Diego

Our pick of the best South Mission Beach Hotel Deals

Sheraton San Diego Resort

Sheraton San Diego Resort

4 out of 5
1380 Harbor Island Dr San Diego CA
Fully refundableReserve now, pay when you stay
The price is NZ$284 per night from 6 Jan to 7 Jan
NZ$284
6 Jan - 7 Jan 2026
includes taxes & fees
8.2/10 Very Good! (3,178 reviews)
Yes , nicest hotel I have ever seen

Reviewed on 15 Dec 2025

Sheraton San Diego Resort
Lafayette Hotel & Club

Lafayette Hotel & Club

4 out of 5
2223 El Cajon Blvd San Diego CA
Fully refundableReserve now, pay when you stay
The price is NZ$453 per night from 6 Jan to 7 Jan
NZ$453
6 Jan - 7 Jan 2026
includes taxes & fees
9.2/10 Wonderful! (1,336 reviews)
Fun place with lots of energy. It is a big party almost all the time. Beware of loud music and this place is not for everyone, but it is very cool!

Reviewed on 15 Dec 2025

Lafayette Hotel & Club
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue San Diego CA
Fully refundableReserve now, pay when you stay
The price is NZ$215 per night from 22 Dec to 23 Dec
NZ$215
22 Dec - 23 Dec
includes taxes & fees
8.8/10 Excellent! (733 reviews)
Room was clean with comfortable bed. View facing the habor is interesting.Outdoor facilities is well coming, nice sitting area. There is an adequate gymn, with treadmill , benche and various free weights, all and all fantastic to get a good workout. Staff are courteous and polite. I would stay again.. ...

Reviewed on 13 Dec 2025

The DEXTRO Little Italy, BW Premier Collection
See all 8,669 properties in South Mission Beach
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a South Mission Beach holiday package cost?
Get set to book, because a getaway to South Mission Beach starts from an enticing . When you bundle your hotels, flights and car rentals into a travel package, you'll score the biggest deals.
How do I get a cheap travel package to South Mission Beach?
Browse and lock in everything in one place with our South Mission Beach holiday packages. You'll discover bargains on hotels, flights, tours and more that'll keep your hip pocket happy and your adventurous spirit alive. And, with more than 550 airlines and 1 000 000 hotel options around the globe to pick from, you'll have the flexibility to mix and match.
Where should I stay in South Mission Beach?
A trip to South Mission Beach isn't over until you've seen La Jolla Cove and University of California, San Diego. Stay somewhere within walking distance for easy access to these popular attractions.
What are the top hotels in South Mission Beach?
Get your trip off to an excellent start by reserving a room at Mission Point, San Diego Hub - 1 Block To Beach. It's one of most sought-after properties in South Mission Beach. Another welcoming option is Mission Bay Retreat.
How far in advance should I book my South Mission Beach holiday?
Reserving your seat early with Expedia means one less thing to worry about. A number of air carriers advertise tickets up to 12 months prior to departure dates. Usually, this is the cheapest time to book. If circumstances have left you booking late, incredible deals to South Mission Beach will sometimes occur a few weeks before departure.
What does an Expedia South Mission Beach travel package include?
Expedia has all you need to plan your South Mission Beach escape, but how your package is structured is up to you. Choose from a combination of rental cars, flights and hotels. After some tours or activities to fill in your time? Once you've made your booking, you can add them too. No matter your style, there's a package to match your needs.
What should I know before booking a South Mission Beach travel package?
You'll pick up big savings when you combine your hotels, flights and rental cars into a travel package. Plus, booking everything in one place just makes things easier. So why waste your money or time? Whether you're organising a ritzy city getaway or a low-cost family road trip, check out our holiday packages today.
Can I choose my airline with a South Mission Beach Expedia holiday package?
You certainly can. We offer more than 550 airline partners around the world, so select the carrier that best suits your budget needs.
If I'm not able to travel, can I cancel my South Mission Beach holiday package?
If your holiday plans in South Mission Beach have been upended, it's good to know that it's possible to cancel your booking. If you made your booking within the last 24 hours, you may be eligible for a refund. If your booking is older than that, your airline, hotel or car rental company may charge a cancellation fee. For more details, check our Customer Service Portal.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.