Siesta Isle Hotels, Fort Myers Beach

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Check prices for these dates

Tonight
14 Nov - 15 Nov
Tomorrow
15 Nov - 16 Nov
Next weekend
20 Nov - 22 Nov
In two weeks
27 Nov - 29 Nov

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Our top choices for Siesta Isle hotels

A row of turquoise Adirondack chairs with umbrellas, a wooden deck, and a marina in the background.

1. Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
2.5 star property
Siesta Isle
9.0 out of 10, Wonderful, (1,001 reviews)
"This place was quiet and very clean, we were able to do kayaking & there's a lot of places to eat around. 3-5min from the beaches, shopping & restaurants."
United States
Maria
The price is NZ$182
includes taxes & fees
15 Nov - 16 Nov
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
A spacious lobby with a high ceiling, a seating area with a sofa and chairs, a small round table, and a decorative wall with artwork.

2. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
3.0 star property
2.6 km from Siesta Isle
8.8 out of 10, Excellent, (1,001 reviews)
"I enjoyed my stay - peaceful, wonderful staff & great location"
United States
Melanie
The price is NZ$192
includes taxes & fees
16 Nov - 17 Nov
Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway
An outdoor patio with tables and chairs, umbrellas, and a pool in the background.

3. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
2.5 star property
2.7 km from Siesta Isle
9.2 out of 10, Wonderful, (1,001 reviews)
"We always stay at this hotel because clean and very close to the beach and trolley line."
United States
William
The price is NZ$204
includes taxes & fees
22 Nov - 23 Nov
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
A modern dining area with wooden flooring, white chairs, and large windows offering a view of the beach.

4. Best Western Plus Beach Resort

Best Western Plus Beach Resort
2.5 star property
2.2 km from Siesta Isle
9.4 out of 10, Exceptional, (1,001 reviews)
"Convenient location, friendly staff and clean rooms."
United States
Stacy
The price is NZ$436
includes taxes & fees
15 Dec - 16 Dec
Best Western Plus Beach Resort
A wooden deck with outdoor seating, a thatched-roof structure, and string lights.

5. Latitude 26 Waterfront Resort & Marina

Latitude 26 Waterfront Resort & Marina
3.0 star property
1.1 km from Siesta Isle
8.6 out of 10, Excellent, (1,001 reviews)
"Great place to stay, especially on a fishing trip!"
United States
Mitchel
The price is NZ$171
includes taxes & fees
15 Nov - 16 Nov
Latitude 26 Waterfront Resort & Marina
A spacious dining area with multiple tables and chairs, large windows, and a modern chandelier.

6. Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel
3.0 star property
2.7 km from Siesta Isle
8.8 out of 10, Excellent, (1,001 reviews)
"Loved the balcony view, breakfast spread, hot tub and heated pool."
United States
Lora
The price is NZ$232
includes taxes & fees
22 Nov - 23 Nov
Residence Inn by Marriott Fort Myers Sanibel
A hotel pool area with multiple lounge chairs and umbrellas, surrounded by a fence and palm trees.

7. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
3.0 star property
2.3 km from Siesta Isle
8.2 out of 10, Very good, (1,412 reviews)
"The staff was very helpful during my stay."
United States
Samantha
The price is NZ$178
includes taxes & fees
23 Nov - 24 Nov
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
A large, clear swimming pool with multiple lounge areas and palm trees.

8. Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers
4.0 star property
2.6 km from Siesta Isle
9.0 out of 10, Wonderful, (2,765 reviews)
"Everything about the resort was excellent"
United States
Lance
The price is NZ$448
includes taxes & fees
15 Nov - 16 Nov
Margaritaville Beach Resort Fort Myers
A swimming pool with lounge chairs and umbrellas, surrounded by palm trees and a stone archway.

9. The Lighthouse Resort Inn & Suites

The Lighthouse Resort Inn & Suites
3.0 star property
2.4 km from Siesta Isle
8.6 out of 10, Excellent, (1,850 reviews)
"excellent place to stay"
United States
Shayne
The price is NZ$198
includes taxes & fees
9 Dec - 10 Dec
The Lighthouse Resort Inn & Suites
A swimming pool with a rock arch structure, a multi-story building with balconies, and palm trees in the background.

10. Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina
4.0 star property
1.8 km from Siesta Isle
9.6 out of 10, Exceptional, (1,490 reviews)
"It's nice place to stay"
United States
Mario
The price is NZ$553
includes taxes & fees
15 Nov - 16 Nov
Pink Shell Beach Resort and Marina
A balcony with wicker furniture, a view of a beach, and a clear sky.

11. Lani Kai Beachfront Resort

Lani Kai Beachfront Resort
3.5 star property
2.7 km from Siesta Isle
8.8 out of 10, Excellent, (2,197 reviews)
"Excellent location"
United States
yeny
The price is NZ$354
includes taxes & fees
9 Dec - 10 Dec
Lani Kai Beachfront Resort
A beachfront hotel with a pool, beach, and ocean view.

12. DiamondHead Beach Resort

DiamondHead Beach Resort
3.5 star property
2.9 km from Siesta Isle
9.2 out of 10, Wonderful, (1,340 reviews)
"Loved our stay"
United States
Dale patrick
The price is NZ$452
includes taxes & fees
14 Dec - 15 Dec
DiamondHead Beach Resort
A balcony with a TV, a chair, and a view of a beach with a pier.

13. Edison Beach House

Edison Beach House
3.5 star property
2.3 km from Siesta Isle
9.4 out of 10, Exceptional, (1,973 reviews)
"Best place ever"
United States
Joshua
The price is NZ$381
includes taxes & fees
17 Nov - 18 Nov
Edison Beach House
A hotel entrance with a sign reading 'Candlewood Suites' and a parking lot with a handicapped parking space.

14. Candlewood Suites Fort Myers Sanibel Gateway by IHG

Candlewood Suites Fort Myers Sanibel Gateway by IHG
3.0 star property
4.9 km from Siesta Isle
7.6 out of 10, Good, (1,000 reviews)
"I was satisfied with the price for a short stay."
United States
James
The price is NZ$157
includes taxes & fees
14 Dec - 15 Dec
Candlewood Suites Fort Myers Sanibel Gateway by IHG
A balcony with tables set for dining, overlooking a beach with palm trees and the ocean.

15. The Bay Inn at Lani Kai

The Bay Inn at Lani Kai
3.0 star property
2.7 km from Siesta Isle
7.8 out of 10, Good, (545 reviews)
"Clean room, helpful staff, very close to the beach."
United States
Andrea
The price is NZ$234
includes taxes & fees
15 Nov - 16 Nov
The Bay Inn at Lani Kai
A modern hotel lobby with a reception desk, seating area, and a dining section.

16. Holiday Inn Express & Suites Fort Myers Airport by IHG

Holiday Inn Express & Suites Fort Myers Airport by IHG
2.5 star property
17.9 km from Siesta Isle
9.4 out of 10, Exceptional, (1,212 reviews)
"For $112 a night can't beat it, great location"
United States
Brian
The price is NZ$204
includes taxes & fees
15 Nov - 16 Nov
Holiday Inn Express & Suites Fort Myers Airport by IHG
A marina with boats docked, surrounded by palm trees and a building with a red-tiled roof.

17. Matanzas Inn Bayside Resort and Marina

Matanzas Inn Bayside Resort and Marina
3.0 star property
2.1 km from Siesta Isle
9.4 out of 10, Exceptional, (1,001 reviews)
"Great staff, amazing food"
United States
Alexandria
The price is NZ$624
includes taxes & fees
16 Nov - 17 Nov
Matanzas Inn Bayside Resort and Marina
A balcony with a table and chairs, large windows, and a view of the sea.

18. The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village
4.0 star property
8.3 km from Siesta Isle
9.0 out of 10, Wonderful, (1,004 reviews)
"Very clean and nice place!"
United States
Charles
The price is NZ$375
includes taxes & fees
13 Dec - 14 Dec
The Westin Cape Coral Resort At Marina Village
A beach with a variety of seashells and pebbles.

19. Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
10.1 km from Siesta Isle
9.2 out of 10, Wonderful, (2,428 reviews)
"Lovely stay. Great staff and relaxing environment."
United States
Victoria
The price is NZ$451
includes taxes & fees
15 Nov - 16 Nov
Sanibel Island Beach Resort
A modern hotel lobby with a wooden floor, leather armchairs, a round table, and a large abstract painting on the wall.

20. Extended Stay America Premier Suites - Fort Myers - Airport

Extended Stay America Premier Suites - Fort Myers - Airport
2.5 star property
12.3 km from Siesta Isle
9.0 out of 10, Wonderful, (1,189 reviews)
"Very Good hotel , lot of parking spot , clean rooms . Recommended!"
Canada
Isaura
The price is NZ$129
includes taxes & fees
15 Nov - 16 Nov
Extended Stay America Premier Suites - Fort Myers - Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Siesta Isle

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A row of turquoise Adirondack chairs with umbrellas, a wooden deck, and a marina in the background.
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
2.5 star property
9.0
Wonderful
1,001 reviews
View
A large, clear swimming pool with multiple lounge areas and palm trees.
Margaritaville Beach Resort Fort Myers
4.0 star property
9.0
Wonderful
2,765 reviews
View
A swimming pool with a rock arch structure, a multi-story building with balconies, and palm trees in the background.
Pink Shell Beach Resort and Marina
4.0 star property
9.6
Exceptional
1,490 reviews
View
A modern dining area with wooden flooring, white chairs, and large windows offering a view of the beach.
Best Western Plus Beach Resort
2.5 star property
9.4
Exceptional
1,001 reviews
View
An outdoor patio with tables and chairs, umbrellas, and a pool in the background.
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
2.5 star property
9.2
Wonderful
1,001 reviews
View

Our guide on where to stay in Siesta Isle

Find the best Siesta Isle areas for the activities you enjoy most.
A sunset over a calm sea with trees framing the view.

Mid Island

While visiting Mid Island, you might make a stop by sights like Estero Boulevard Beach and Sterling Ave Beach.

A pier extending into the water with two gazebos at the end, under a sunset sky.

South Island

While visiting South Island, you might make a stop by sights like Santini Marina Shopping Plaza and Castle Beach.

A coastal town with a marina, residential buildings, and a clear view of the ocean.

TP Hill's

When in TP Hill's, you can plan a visit to Key West Express and Estero Boulevard Beach, some noteworthy sights in the nearby area.

A beach at sunset with a pink and purple sky, people walking, and a lifeguard tower in the distance.
Photo by Abby Chase
Open Photo by Abby Chase

Downtown Fort Myers Beach

If you're spending some time in Downtown Fort Myers Beach, Lynn Hall Memorial Park and Estero Boulevard Beach are top sights worth seeing.

A coastal town with a beach, buildings, and a road.

Winklers

Winklers might not have many top sights, but Key West Express and Estero Boulevard Beach are two attractions nearby that you can check out.

Top Siesta Isle Hotel Reviews

A modern dining area with wooden flooring, white chairs, and large windows offering a view of the beach.
Best Western Plus Beach Resort

Best Western Plus Beach Resort

Best Western Plus Beach Resort
Fort Myers Beach

10/10 Excellent

Location was great. The room was really nice too. I liked the beach vibe of the room and the view.
Australia
Triin
Reviewed January 28, 2026
Best Western Plus Beach Resort

Frequently Asked Questions

What is Siesta Isle like?

Travellers will be sure to find plenty to entertain them in Fort Myers Beach's Siesta Isle neighbourhood. Consider a visit to San Carlos Bay - Bunche Beach Preserve as part of your Siesta Isle travel plans.

Where is the best place to stay in Siesta Isle?

Based on our traveller data, Latitude 26 Waterfront Boutique Resort - Fort Myers Beach is one of the top choices for your stay in Siesta Isle. This hotel offers a marina and free breakfast.

How many hotels will I find in the Siesta Isle area?

If you're searching for places to stay in Fort Myers Beach, Expedia has something to meet your needs with 27 Siesta Isle hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in Siesta Isle, will I receive a refund?

Yes! You'll find that most hotel reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view the best deals in Siesta Isle.

What are the top things to see and do in Siesta Isle?

San Carlos Bay - Bunche Beach Preserve is an attraction you might want to check out while you're in Siesta Isle. Key West Express and Bunche Beach are also worth a visit when you're out sightseeing in Fort Myers Beach.