Santa Cruz Holidays

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Our guide on where to stay in Santa Cruz

Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz
A tree-lined street with parked motorcycles and cars, and a person walking.

Historical Center

7 out of top 10 points of interest in this area

Go on an adventure through the ages when you visit the historical churches, palaces, plazas and mansions of Seville’s ancient heart.

A courtyard with a curved building, columns, and a fountain.

El Arenal

Travellers choose El Arenal for its abundant dining options. Hop aboard the metro at Plaza Nueva Tram Stop or Archivo de Indias Tram Stop and check out top sights like Paseo de Cristóbal Colón.

A bustling outdoor café area with people dining and walking.

Alfalfa

Unique features of Alfalfa include the bars and historical sites. Make a stop by Salvador Plaza or Calle Sierpes while you're exploring the area.

A riverside promenade with a bridge, historic buildings, and a calm river.

Triana

2 out of top 10 points of interest in this area

Get lost in the narrow lanes of the city’s old Roma quarter, known for its flamenco history and ceramics workshops.

A modern stadium with a unique curved roof structure, surrounded by urban buildings and a prominent tower in the background.

San Bartolomé

Travellers come to San Bartolomé for its lively bars, and you can see top attractions like Pilate's House and Zurbarán Statue while you're in town.

Our pick of the best Santa Cruz Hotel Deals

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville

San Fernando 2 Seville Seville
Fully refundableReserve now, pay when you stay
NZ$695
26 Aug - 27 Aug
includes taxes & fees
9.4/10 Exceptional! (1,002 reviews)
"It was lovely"

Reviewed on 16 Aug 2026

Hotel Alfonso XIII, a Luxury Collection Hotel, Seville
Las Casas de la Judería, Sevilla Historic City Center

Las Casas de la Judería, Sevilla Historic City Center

Calle Santa Maria La Blanca 5 Seville Seville
Fully refundableReserve now, pay when you stay
NZ$231
26 Aug - 27 Aug
includes taxes & fees
9.2/10 Wonderful! (1,013 reviews)
"Very unique style, beautiful and well worth exploring. We only discovered the underground tunnel just before we left. Charming"

Reviewed on 15 Aug 2026

Las Casas de la Judería, Sevilla Historic City Center
Hotel Amadeus Sevilla

Hotel Amadeus Sevilla

Calle Farnesio 6 Seville Seville
Fully refundableReserve now, pay when you stay
NZ$243
19 Aug - 20 Aug
includes taxes & fees
9.6/10 Exceptional! (1,247 reviews)
"A friend and I stayed here for 3 nights in August and it was a nice hotel. Location is 10/10. Beautiful and very walkable to absolutely everything. Dining options galore. The property itself is beautifully decorated and very welcoming. Staff were helpful and friendly. Our room was very cute but it ..."

Reviewed on 11 Aug 2026

Hotel Amadeus Sevilla
See all 411 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Cruz holiday package cost?
Get ready to book, because a trip to Santa Cruz starts from a tempting . When you combine your hotels, flights and car rentals into a package, you'll enjoy the biggest deals.
How do I get a cheap travel package to Santa Cruz?
Just think of all the fun things you could do in Santa Cruz with a pile of extra cash in your pocket. Watch your savings stack up when you combine your travel bookings into a Santa Cruz holiday package. You have plenty of choice when it comes to booking with Expedia too. In fact, you can select from over 550 airlines and 1 000 000 properties around the world. Whether you're enjoying a break with the whole family or travelling with someone special, exploring Santa Cruz is better with a package.
Where should I stay in Santa Cruz?
Most people who visit Santa Cruz put both Seville Cathedral and Alcázar on their must-see lists. Why not choose a hotel close to one of these iconic attractions?
What are the top hotels in Santa Cruz?
Puerta Catedral Holiday Suites and San Isidoro Hostel Sevilla are among the most well-known properties in Santa Cruz. Why not check out the rates and facilities at each and then make up your mind?
How far in advance should I book my Santa Cruz holiday?
Reserving your seat early with Expedia means one less thing to have to worry about. Most carriers advertise prices up to 12 months prior to take off. This is generally the cheapest time to book. If circumstances have left you booking late, great deals to Santa Cruz sometimes emerge in the weeks leading up to departure.
What does an Expedia Santa Cruz travel package include?
Hotels, car rentals and flights — we bring you the very best deals. All you'll have to do is decide on your ideal combination. Once you've made your booking, you can add on the fun stuff like activities and tours. Our travel packages make it easy to craft an awesome Santa Cruz trip.
What should I know before booking a Santa Cruz travel package?
You'll pick up impressive savings when you bundle your flights, hotels and rental cars into a package. Plus, booking everything in one place just makes things easier. So why waste your time or money? Whether you're putting together an upscale romantic escape or a budget family adventure, explore our holiday packages today.
Can I choose my airline with a Santa Cruz Expedia holiday package?
Yes — that's the beauty of an Expedia package. You're in control. We have more than 550 airline partners around the world, so you have loads of choice when organising your Santa Cruz getaway.
If I'm not able to travel, can I cancel my Santa Cruz holiday package?
Yes, it's possible to cancel your Santa Cruz booking if your travel plans have changed. Whether you'll be charged a fee or not depends on your airline, hotel or car rental company. You may be able to change or cancel for free if you booked in the last 24 hours. Visit our Customer Service Portal to learn more.

Stay near popular Santa Cruz attractions

A courtyard with a central water feature, surrounded by columns and potted trees.

Royal Alcázar of Seville

9.6/10 (8,220 reviews)
This group of palaces and gardens in central Seville has been built and rebuilt over hundreds of years, forging a sensational combination of architectural styles.
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A tall, ornate tower with intricate patterns and a statue on top, surrounded by historic buildings.

Giralda Tower

9.4/10 (6,353 reviews)
Now the bell tower of Seville Cathedral, this striking landmark began life as the minaret of an Almohad mosque.
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University of Seville

8.6/10 (1,316 reviews)
Explore the campus of University of Seville during your travels in Paseo de Las Delicias. Visit the shops and stunning cathedral in this culturally rich area.
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Santa Cruz Church

8.6/10 (26 reviews)
After visiting Santa Cruz Church, make a plan to see the other sights and activities in Seville. Visit the shops and top-notch restaurants in this romantic area.
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Murillo Gardens

9.2/10 (9 reviews)
Explore the great outdoors at Murillo Gardens, a lovely green space in Seville. Visit the shops and stunning cathedral in this family-friendly area.
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General Archive of the Indies

8.0/10 (11 reviews)
You can study the exhibits at General Archive of the Indies, a museum with a story of its own, during your travels to Seville. Visit the shops and lively bars in this culturally rich area.
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Santa María la Blanca Church

8.4/10 (8 reviews)
After visiting Santa María la Blanca Church, make a plan to see the other sights and activities in Seville. Visit the stunning cathedral and top-notch restaurants in this culturally rich area.
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Juderia de Sevilla Interpretation Center

10.0/10 (4 reviews)
You can study the exhibits at Juderia de Sevilla Interpretation Center, a museum with a storied past, during your trip to Seville. Visit the shops and stunning cathedral in this romantic area.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.