Santa Ana Hotels, Antigua Guatemala

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Check prices for these dates

Tonight
31 Jan - 1 Feb
Tomorrow
1 Feb - 2 Feb
Next weekend
6 Feb - 8 Feb
In two weeks
13 Feb - 15 Feb

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Our top choices for Santa Ana hotels

Front of property

Casa Buho B&B

Casa Buho B&B
3.0 star property
Santa Ana
9.2 out of 10, Wonderful, (49 reviews)
"Great place !!"
United States
Abner Israel Polanco
The price is NZ$109
includes taxes & fees
1 Feb - 2 Feb
Casa Buho B&B
Front of property

Villas Santa Ana-Ricardo

Villas Santa Ana-Ricardo
3.5 star property
Santa Ana
8.6 out of 10, Excellent, (12 reviews)
"Space was clean and had a cozy vibe."
United States
Evelin
Villas Santa Ana-Ricardo
Garden view

Hostal Casa Buho

Hostal Casa Buho
3.0 star property
Santa Ana
8.6 out of 10, Excellent, (22 reviews)
"A little too far from everything but as long as you have a car is ok plenty of parking there"
United States
Gustavo
The price is NZ$89
includes taxes & fees
14 Feb - 15 Feb
Hostal Casa Buho
Garden

Hilton Guatemala City

Hilton Guatemala City
4.5 star property
25.9 km from Santa Ana
8.6 out of 10, Excellent, (695 reviews)
"The hotel property in excellent condition and very quiet and safe."
United States
Roger
The price is NZ$299
includes taxes & fees
1 Mar - 2 Mar
Hilton Guatemala City
View from property

AC Hotel by Marriott Guatemala City

AC Hotel by Marriott Guatemala City
4.0 star property
26.4 km from Santa Ana
8.6 out of 10, Excellent, (1,001 reviews)
"Beautiful place!"
United States
Beth
The price is NZ$239
includes taxes & fees
20 Feb - 21 Feb
AC Hotel by Marriott Guatemala City
Interior

Hotel Vista Quince

Hotel Vista Quince
5.0 star property
25.5 km from Santa Ana
8.6 out of 10, Excellent, (236 reviews)
"Staff very pleasant and service oriented "
Canada
osbin
The price is NZ$301
includes taxes & fees
15 Feb - 16 Feb
Hotel Vista Quince
Restaurant

Villas Santander - Deluxe Stay

Villas Santander - Deluxe Stay
3.0 star property
24.7 km from Santa Ana
7.4 out of 10, Good, (230 reviews)
"The balcony view was a little scenic. Enjoyed how clean the rooms were "
United States
Rosa
The price is NZ$71
includes taxes & fees
5 Feb - 6 Feb
Villas Santander - Deluxe Stay
Flat-screen TV

Casa Mesa

Casa Mesa
2.0 star property
24.2 km from Santa Ana
8.6 out of 10, Excellent, (35 reviews)
"Very good option for staying "
United States
Adrian
The price is NZ$80
includes taxes & fees
1 Feb - 2 Feb
Casa Mesa
Restaurant

Villa Sicilia

Villa Sicilia
2.0 star property
24 km from Santa Ana
7.8 out of 10, Good, (82 reviews)
"Everything was as advertised and good location "
United States
Jimmy
The price is NZ$57
includes taxes & fees
3 Mar - 4 Mar
Villa Sicilia
Bar (on property)

Ever Green Hotel

Ever Green Hotel
3.5 star property
23.8 km from Santa Ana
8.8 out of 10, Excellent, (70 reviews)
"Great room, nice location and decent complimentary breakfast. We would stay again. Great value"
United States
Rony
Ever Green Hotel
Front of property

La Inmaculada Hotel

La Inmaculada Hotel
3.5 star property
23.7 km from Santa Ana
9.2 out of 10, Wonderful, (618 reviews)
"Great staff, convenient location, hotel has everything it offers."
United States
Colin
La Inmaculada Hotel
Hallway

Hotel Ciudad Vieja

Hotel Ciudad Vieja
3.0 star property
23.7 km from Santa Ana
9.2 out of 10, Wonderful, (224 reviews)
"Great secure location near restaurants. Very quiet and great breakfast choices. Staff were attentive and arranged for taxis and an airport pickup."
United States
Stephen
Hotel Ciudad Vieja
Terrace/patio

Meraki Boutique Hotel

Meraki Boutique Hotel
3.5 star property
23.4 km from Santa Ana
9.0 out of 10, Wonderful, (411 reviews)
"Cute hotel, comfortable room, and kind staff. Its in a great location too. We will be staying here again. "
United States
Elizabeth
The price is NZ$156
includes taxes & fees
21 Feb - 22 Feb
Meraki Boutique Hotel
Free daily full breakfast

Hotel Santander Plaza

Hotel Santander Plaza
3.5 star property
23.3 km from Santa Ana
8.2 out of 10, Very good, (572 reviews)
"Breakfast was delicious with a lot of options to choose, staff very kind good service "
United States
Monica
The price is NZ$199
includes taxes & fees
4 Feb - 5 Feb
Hotel Santander Plaza
Breakfast, lunch, dinner served; international cuisine, garden views

Clarion Suites Guatemala City

Clarion Suites Guatemala City
4.0 star property
23.3 km from Santa Ana
9.2 out of 10, Wonderful, (1,006 reviews)
"Great location, good size room, very helpful staff."
United States
Hugo
The price is NZ$221
includes taxes & fees
27 Feb - 28 Feb
Clarion Suites Guatemala City
Garden

Good Hotel Guatemala City

Good Hotel Guatemala City
3.0 star property
23.9 km from Santa Ana
9.4 out of 10, Exceptional, (275 reviews)
"Great restaurant in house, friendly staff! Nice stay, and the money goes to a great cause"
United States
Nathaniel
The price is NZ$235
includes taxes & fees
2 Mar - 3 Mar
Good Hotel Guatemala City
Exterior

Hyatt Centric Guatemala City

Hyatt Centric Guatemala City
4.5 star property
23.3 km from Santa Ana
9.6 out of 10, Exceptional, (828 reviews)
"Great location. "
United States
Christian
The price is NZ$308
includes taxes & fees
14 Feb - 15 Feb
Hyatt Centric Guatemala City
View from property

Best Western Plus Hotel Stofella

Best Western Plus Hotel Stofella
4.0 star property
23.3 km from Santa Ana
8.8 out of 10, Excellent, (1,001 reviews)
"Great breakfast buffet"
United States
Loyell
The price is NZ$190
includes taxes & fees
20 Feb - 21 Feb
Best Western Plus Hotel Stofella
4 restaurants, breakfast, lunch, dinner served; international cuisine

InterContinental Real Guatemala by IHG

InterContinental Real Guatemala by IHG
5.0 star property
23.2 km from Santa Ana
9.2 out of 10, Wonderful, (1,002 reviews)
"Very nice room and service was great! "
United States
Henry
The price is NZ$342
includes taxes & fees
15 Feb - 16 Feb
InterContinental Real Guatemala by IHG
Superior Double Room

Hotel Royal Palace

Hotel Royal Palace
3.0 star property
24.5 km from Santa Ana
8.2 out of 10, Very good, (149 reviews)
"The hotel is well located there is a lot of stores and restaurants with in a walking distance."
United States
luis
The price is NZ$187
includes taxes & fees
1 Feb - 2 Feb
Hotel Royal Palace
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our guide on where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.

Historic Center

If you're spending some time in Historic Center, Central Park and Santa Catalina Arch are top sights worth seeing.

Barrio de La Concepción

While visiting Barrio de La Concepción, you might make a stop by sights like Casa Santo Domingo Museum and Jade Maya Factory and Museum.

Top Santa Ana Hotel Reviews

Hotel Biltmore Guatemala

Hotel Biltmore Guatemala

10/10 Excellent
"I had a great stay at Hotel Biltmore Guatemala. The rooms are clean, spacious, and very comfortable, and the staff is friendly and attentive. The hotel’s location in Zona 10 is perfect—close to restaurants, shops, and easy access to the airport. The breakfast is tasty and a convenient way to start the day. Overall, it’s a modern, well-maintained hotel with excellent value, ideal for both business and leisure travelers."
Francisco 2-night trip
Posted 3 days ago
Hotel Biltmore Guatemala

Frequently asked questions

What's it like in Santa Ana?
Travellers to the Santa Ana neighbourhood in Antigua Guatemala will be sure to enjoy their stay.
What's a favourite place to stay in Santa Ana?
Based on Expedia customer reviews, Casa Buho B&B is the highest ranked property in Santa Ana. This hotel offers a restaurant and free parking. Another top choice in the area is Hostal Casa Buho.
How many hotels will I be able to find in Santa Ana?
If you're searching for places to stay in Antigua Guatemala, choose from one of Expedia's 16 hotels and other accommodation options in Santa Ana.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view top deals in Santa Ana.
What are the top things to see and do in Santa Ana?
House of the Giants, Santa Clara Convent and Jade Maya Factory and Museum are just a few of the places to visit in and around Santa Ana. While you're out sightseeing in Antigua Guatemala, make sure that you visit other sights such as Tanque La Unión or Museo del Hermano Pedro.