Search Mesilla hotels

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Mesilla hotels

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
3.0 star property
Las Cruces
8.2 out of 10, Very good, (2308)
"Great staff!! Small hotel,older, BUT close by everything!!!"
United States
deborah
The price is NZ$119
includes taxes & fees
25 Jan - 26 Jan 2026
La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

Days Inn by Wyndham Las Cruces

Days Inn by Wyndham Las Cruces
2.5 star property
Las Cruces
8.2 out of 10, Very good, (1307)
"Friendly staff and spacious King room."
United States
Donald
The price is NZ$103
includes taxes & fees
19 Jan - 20 Jan 2026
Days Inn by Wyndham Las Cruces

Hampton Inn & Suites Las Cruces I-10

Hampton Inn & Suites Las Cruces I-10
2.5 star property
Las Cruces
8.8 out of 10, Excellent, (1001)
In Las Cruces, this hotel offers free breakfast, WiFi, and parking near Luna Rossa Winery. Take a morning swim in the indoor pool, work out at the fitness centre, and experience the clean rooms and helpful staff praised by guests.

"Clean, great staff, comfortable rooms. "
United States
Lizette
The price is NZ$179
includes taxes & fees
11 Jan - 12 Jan 2026
Hampton Inn & Suites Las Cruces I-10

Hotel Encanto de Las Cruces

Hotel Encanto de Las Cruces
3.5 star property
Las Cruces
9.0 out of 10, Wonderful, (1613)
Experience serene relaxation at this historical hotel featuring an outdoor pool with stunning sunset mountain vistas. Enjoy authentic Mexican cuisine at Gardunos, unwind at one of 3 bars, and easily access nearby Mesilla Valley Mall.

"Great location fun vibes "
United States
Joe
The price is NZ$271
includes taxes & fees
1 Jan - 2 Jan 2026
Hotel Encanto de Las Cruces

Motel 6 Las Cruces, NM - Telshor

Motel 6 Las Cruces, NM - Telshor
2.0 star property
Las Cruces
7.2 out of 10, Good, (1000)
"Was a nice stay "
United States
Gerald
The price is NZ$123
includes taxes & fees
3 Jan - 4 Jan 2026
Motel 6 Las Cruces, NM - Telshor

Best Western Mission Inn

Best Western Mission Inn
2.5 star property
Las Cruces
8.8 out of 10, Excellent, (1227)
Located in Las Cruces, this quiet hotel offers comfortable beds and a relaxing outdoor pool. Start each day with a complimentary buffet breakfast, and enjoy free parking. Helpful staff and nearby restaurants enhance the experience, all minutes from NMSU.

"Rooms,staff, good location "
United States
Katsiaryna
The price is NZ$171
includes taxes & fees
12 Jan - 13 Jan 2026
Best Western Mission Inn

Ramada Hotel & Conference Center by Wyndham Las Cruces

Ramada Hotel & Conference Center by Wyndham Las Cruces
3.0 star property
Las Cruces
8.0 out of 10, Very good, (1007)
Relax in this peaceful Las Cruces hotel featuring a beautiful courtyard and full-service spa offering massages and mani/pedis. Take a morning swim in the indoor pool, work out in the 24-hour fitness centre, and enjoy free WiFi and parking.

"We love this hotel. It’s absolutely gorgeous. "
United States
Maria
The price is NZ$149
includes taxes & fees
11 Jan - 12 Jan 2026
Ramada Hotel & Conference Center by Wyndham Las Cruces

Super 8 by Wyndham Las Cruces/White Sands Area

Super 8 by Wyndham Las Cruces/White Sands Area
2.0 star property
Las Cruces
7.2 out of 10, Good, (1009)
Situated close to New Mexico State University, this Las Cruces hotel provides complimentary on-the-go breakfast and WiFi. Guests enjoy the seasonal outdoor pool after exploring nearby Sonoma Ranch Golf Course and Red Hawk Golf Club.

"It was good. I would stay again "
United States
Douglas
The price is NZ$99
includes taxes & fees
22 Jan - 23 Jan 2026
Super 8 by Wyndham Las Cruces/White Sands Area

Hilton Garden Inn Las Cruces

Hilton Garden Inn Las Cruces
3.0 star property
Las Cruces
9.2 out of 10, Wonderful, (1001)
Experience comfort at this Las Cruces hotel near Aggie Memorial Stadium and Pan American Centre. Enjoy Great American Grille's breakfast and dinner, relax in the spa pool, or maintain your routine in the 24-hour fitness centre. Clean rooms include refrigerators and microwaves.

"Great stay"
United States
Myles
The price is NZ$180
includes taxes & fees
11 Jan - 12 Jan 2026
Hilton Garden Inn Las Cruces

Hampton Inn & Suites Las Cruces I-25

Hampton Inn & Suites Las Cruces I-25
2.5 star property
Las Cruces
8.4 out of 10, Very good, (1000)
"Great staff, coffee for guests."
United States
Valerie Isabelle
The price is NZ$179
includes taxes & fees
19 Jan - 20 Jan 2026
Hampton Inn & Suites Las Cruces I-25

Drury Inn & Suites Las Cruces

Drury Inn & Suites Las Cruces
3.0 star property
Las Cruces
9.4 out of 10, Exceptional, (1002)
This business-friendly hotel offers a relaxing indoor pool and spa pool. Wake up to free breakfast, then drive to nearby attractions like Luna Rossa Winery and Rio Grande Vineyards. Guests consistently praise the helpful staff and convenient free parking.

"Clean room and food take great for dinner and breakfast."
United States
Lori
The price is NZ$188
includes taxes & fees
11 Jan - 12 Jan 2026
Drury Inn & Suites Las Cruces

Comfort Suites Las Cruces I-25 North

Comfort Suites Las Cruces I-25 North
2.5 star property
Las Cruces
9.2 out of 10, Wonderful, (1001)
Experience Las Cruces with a splash in the indoor pool, relaxing spa pool, and rejuvenating spa services at this welcoming hotel. Enjoy free breakfast, WiFi, and parking while being close to Mesilla Valley Mall and Sonoma Ranch Golf Course.

"Clean room, friendly staff and good location"
United States
PHILIP
The price is NZ$218
includes taxes & fees
29 Jan - 30 Jan 2026
Comfort Suites Las Cruces I-25 North

Holiday Inn Express & Suites Las Cruces North by IHG

Holiday Inn Express & Suites Las Cruces North by IHG
2.5 star property
Las Cruces
9.0 out of 10, Wonderful, (985)
Located in Las Cruces, this hotel features an indoor pool and spa pool for year-round relaxation. Clean rooms include refrigerators and microwaves. Enjoy free breakfast, WiFi, and parking while being close to Branigan Cultural Centre and local attractions.

"Staff is great rooms nice and clean "
United States
William
The price is NZ$237
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express & Suites Las Cruces North by IHG

Staybridge Suites Las Cruces by IHG

Staybridge Suites Las Cruces by IHG
3.0 star property
Las Cruces
8.8 out of 10, Excellent, (1003)
Immerse yourself in Las Cruces convenience at this welcoming hotel with free breakfast, WiFi, and parking. Take a morning swim in the outdoor pool, relax in the spa pool, and maintain your routine in the fitness centre.

"Clean rooms with excellent breakfast. Great variety."
United States
SUBRAT SURYAKANT
The price is NZ$190
includes taxes & fees
17 Jan - 18 Jan 2026
Staybridge Suites Las Cruces by IHG

Comfort Inn & Suites Las Cruces Mesilla

Comfort Inn & Suites Las Cruces Mesilla
2.5 star property
Las Cruces
8.8 out of 10, Excellent, (1002)
This business-friendly Las Cruces hotel offers a refreshing indoor pool, spa pool, and fitness centre. Each room includes a refrigerator and microwave. Luna Rossa Winery and Rio Grande Vineyards are nearby, with free breakfast, WiFi, and parking.

"Staff was courteous, rooms were comfortable. "
United States
Ronn
The price is NZ$201
includes taxes & fees
18 Jan - 19 Jan 2026
Comfort Inn & Suites Las Cruces Mesilla

Comfort Suites University Las Cruces

Comfort Suites University Las Cruces
2.5 star property
Las Cruces
8.0 out of 10, Very good, (1003)
Adjacent to a golf course, this Las Cruces hotel offers a peaceful atmosphere praised by travellers. The indoor pool provides morning refreshment while the fitness centre keeps workouts on track. Located in a safe area close to Aggie Memorial Stadium with free breakfast, WiFi, and parking.

"Amazing staff, clean rooms, great breakfast "
United States
Michelle
The price is NZ$160
includes taxes & fees
11 Jan - 12 Jan 2026
Comfort Suites University Las Cruces

Home2 Suites by Hilton Las Cruces

Home2 Suites by Hilton Las Cruces
3.0 star property
Las Cruces
9.4 out of 10, Exceptional, (665)
Enjoy morning workouts in the 24-hour fitness centre before exploring Sonoma Ranch Golf Course and Branigan Cultural Centre. Clean rooms await your return, with free breakfast, WiFi and parking enhancing your comfortable stay.

"Room was spotless and staff was very professional."
United States
Friedrich
The price is NZ$246
includes taxes & fees
4 Jan - 5 Jan 2026
Home2 Suites by Hilton Las Cruces

Courtyard by Marriott Las Cruces at NMSU

Courtyard by Marriott Las Cruces at NMSU
3.0 star property
Las Cruces
9.2 out of 10, Wonderful, (511)
Located near New Mexico State University, this hotel offers an outdoor pool and The Bistro restaurant for breakfast and dinner. Enjoy the 24-hour fitness centre and bar after exploring nearby American Southwest Theatre Company and Pan American Centre.

"Courteous staff and clean rooms"
United States
David
The price is NZ$261
includes taxes & fees
24 Jan - 25 Jan 2026
Courtyard by Marriott Las Cruces at NMSU

Quality Inn & Suites Las Cruces - University Area

Quality Inn & Suites Las Cruces - University Area
2.5 star property
Las Cruces
7.0 out of 10, Good, (1001)
This quiet hotel offers free parking and a peaceful atmosphere near Luna Rossa Winery and Rio Grande Vineyards. Guests praise the helpful staff, clean rooms, and overall property condition. Enjoy a comfortable stay just 52 minutes from El Paso International Airport.

"Great place to stay "
United States
Derek
The price is NZ$104
includes taxes & fees
29 Jan - 30 Jan 2026
Quality Inn & Suites Las Cruces - University Area

Towneplace Suites by Marriott Las Cruces

Towneplace Suites by Marriott Las Cruces
3.0 star property
Las Cruces
8.6 out of 10, Excellent, (144)
Discover this hotel with outdoor pool and spa pool near Sonoma Ranch Golf Course. Take advantage of free breakfast, WiFi, and parking. The fitness centre and snack bar add convenience while sofa beds offer extra sleeping space.

"Loved the suite with Full Kitchen! We also enjoyed the breakfast buffet and the pool!"
United States
LAURIE
The price is NZ$219
includes taxes & fees
5 Jan - 6 Jan 2026
Towneplace Suites by Marriott Las Cruces
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Mesilla attractions

Learn more about Mesilla

Historic adobe buildings surround the plaza where Billy the Kid once stood trial in this charming town. Explore local art galleries and sample authentic Mexican cuisine at La Posta, a restaurant housed in a 19th-century stagecoach stop.

Red chile doorway Mesilla NM

Top Mesilla Hotel Reviews

More cheap accommodation in Mesilla

Frequently asked questions

What's the best place for a stay in Mesilla?
Located 4.5 mi (7.3 km) from the heart of Mesilla, Hotel Encanto de Las Cruces is a top choice for your stay, based on our traveller data. Other good choices for your visit to the area are La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain and Days Inn by Wyndham Las Cruces. See all available top hotels, or vacation rentals in Mesilla.
What are some of the best holiday rentals that Mesilla has to offer?
Casita Azul, Mesilla Plaza Only Steps Away: This highly rated holiday home rental in Mesilla is located on a lake, and has a patio, a BBQ and air conditioning to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop and a microwave. You and your friends and family can relax into your holiday with amenities such as a selection of books. See all vacation rentals in Mesilla.
If I need to cancel my hotel reservation in Mesilla, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a reservation that's non-refundable, you might be able to cancel it and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Mesilla.
What are some hotels with pools in Mesilla?
Hotel Encanto de Las Cruces: Hotel located near New Mexico State University. Provides 3 bars, an outdoor pool and a 24-hour fitness centre. La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain and Days Inn by Wyndham Las Cruces are two additional hotels that offer an on-site pool. View all hotels with pools in Mesilla.
What is staying in Mesilla like?
Visitors can enjoy all that Mesilla has to offer, including the restaurants, shopping and theatres. In Mesilla, there are 14 hotels and other accommodation options to choose from. Find out more about Mesilla.
What should I do while I'm visiting Mesilla?
Cultural venues include Fountain Theatre and Fountain Theater. Landmarks like Mesillia Plaza and San Albino Basilica might be worth a visit. Additionally, you might want to add Rio Grande to your itinerary. Take a look at what more there is to see and do in Expedia's Mesilla guide.
What's the seasonal weather in Mesilla?
The hottest months are usually June and July, with an average temperature of 28°C, while the coldest months are January and December, with an average of 9°C. Average annual precipitation for Mesilla is 227 mm.