A wooden cart with large wheels in a desert landscape with ancient, earthen structures in the background.

Holiday Homes in Mesilla

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
13 Nov - 15 Nov
In two months
25 Dec - 27 Dec
In three months
22 Jan - 24 Jan
In four months
19 Feb - 21 Feb

Our top choices for Mesilla holiday homes

A building entrance with a wooden door, a brick pathway, and a decorative wreath.

1. Charming Casita in historic Town of Mesilla, NM 2392 Calle de Parian

Charming Casita in historic Town of Mesilla, NM 2392 Calle de Parian
Mesilla
10.0 out of 10, Exceptional, (97 reviews)
"Outstanding. Will definitely stay again."
United States
Glenn N.
The price is NZ$487
includes taxes & fees
1 Nov - 2 Nov
Charming Casita in historic Town of Mesilla, NM 2392 Calle de Parian
A rustic outdoor area with a wooden pergola, a large terracotta pot, and a stone wall.

2. 2 bed, yard, pet friendly in Historic Mesilla.

2 bed, yard, pet friendly in Historic Mesilla.
Las Cruces
10.0 out of 10, Exceptional, (3 reviews)
"We liked the location and homey feeling. Nice to have a yard and chiminea, though we didn't use it this trip."
United States
Tom K.
The price is NZ$540
includes taxes & fees
15 Nov - 16 Nov
2 bed, yard, pet friendly in Historic Mesilla.
A hallway with a white console table, a mirror, decorative wall art, and potted plants.

3. Charming 2-bedroom Casita In Mesilla Park Casita Conway #5

Charming 2-bedroom Casita In Mesilla Park Casita Conway #5
Las Cruces
10.0 out of 10, Exceptional, (14 reviews)
"This casita is beautiful, welcoming, and comfortable! Everything was perfect for our family of 5. Everything was clean, beds were comfortable, air conditioning was awesome. We had such a wonderful stay! I would definitely stay again if we are in the area again. Thank you for your hospitality."
United States
Tiffany
The price is NZ$301
includes taxes & fees
3 Nov - 4 Nov
Charming 2-bedroom Casita In Mesilla Park Casita Conway #5
A kitchen with wooden cabinets, a stainless steel sink, a microwave, and a stove.

4. Charming 1-bedroom house with WiFi, AC Mesilla Park Las Cruces Casita Conway 2

Charming 1-bedroom house with WiFi, AC Mesilla Park Las Cruces Casita Conway 2
Las Cruces
9.2 out of 10, Wonderful, (19 reviews)
"Such a cute place, very clean and comfortable. We really enjoyed our visit. Would definitely stay there again!"
United States
Reina R.
The price is NZ$289
includes taxes & fees
30 Nov - 1 Dec
Charming 1-bedroom house with WiFi, AC Mesilla Park Las Cruces Casita Conway 2
A dining area with a table set for two, blue upholstered chairs, a yellow chair, and a floral centerpiece.

5. Unique 1-bedroom casita in Mesilla Park with hot tub

Unique 1-bedroom casita in Mesilla Park with hot tub
Las Cruces
9.8 out of 10, Exceptional, (30 reviews)
"Super cute casita. Small but perfect for me and my husband. Could easily be room enough for 4! Hot tub was great and easy to use. Bed was super comfy. House was clean and well decorated. Private porch was lovely! Parking was right out front. 10/10 great stay"
United States
Reagan L.
The price is NZ$289
includes taxes & fees
1 Nov - 2 Nov
Unique 1-bedroom casita in Mesilla Park with hot tub
A kitchen with light green cabinets, a stainless steel oven, a microwave, and a sink.

6. 1 bedroom near NMSU. W/D in unit/pets welcome.

1 bedroom near NMSU. W/D in unit/pets welcome.
Las Cruces
10.0 out of 10, Exceptional, (2 reviews)
"This property was a perfect stop over for a couple of nights. What made it so perfect is that we could bring our fur babies with us. We especially appreciated the fenced in back yard. The house itself had all the modern conveniences of home. The fresh eggs and muffins were a wonderful surprise."
United States
Debbie B.
The price is NZ$408
includes taxes & fees
2 Nov - 3 Nov
1 bedroom near NMSU. W/D in unit/pets welcome.
A living room with a sofa, coffee table, and a fireplace.

7. 3 bed 2 bath Hacienda near Downtown and NMSU.

3 bed 2 bath Hacienda near Downtown and NMSU.
Las Cruces
10.0 out of 10, Exceptional, (1 review)
"Such an adorable place to stay! We stopped through for one night on our way to our destination. The beds were comfortable and the house was so unique. We loved the fresh eggs for breakfast!"
United States
Sarah E.
The price is NZ$653
includes taxes & fees
3 Nov - 4 Nov
3 bed 2 bath Hacienda near Downtown and NMSU.
A living room with a brown sofa and a dining area with a wooden table and chairs.

8. Pet-Friendly 2BR Near NMSU | Fenced Yard + BBQ

Pet-Friendly 2BR Near NMSU | Fenced Yard + BBQ
Las Cruces
The price is NZ$427
includes taxes & fees
31 Oct - 1 Nov
Pet-Friendly 2BR Near NMSU | Fenced Yard + BBQ
A dining area with a table and chairs, a hanging light fixture, a microwave, and a dishwasher.

9. 2 bed with W/D, pets ok, 5 min to Farmers Market

2 bed with W/D, pets ok, 5 min to Farmers Market
Las Cruces
8.0 out of 10, Very good, (1 review)
"Was a bit difficult to get into the house on first. Told the key pad numbers but didn't tell us to press KWIKSET. Then, to go leave, we didn't know that we just press KWICKSET. It would have been hpful to know all of that in the initial email. In addition, the key pad is at the front door NOT the back door. "
United States
Elaine
The price is NZ$497
includes taxes & fees
1 Nov - 2 Nov
2 bed with W/D, pets ok, 5 min to Farmers Market
A kitchen with granite countertops, a stove, and a dining area with a table and chairs.

10. Modern New Mexico Loft in the heart of Las Cruces.

Modern New Mexico Loft in the heart of Las Cruces.
Las Cruces
The price is NZ$438
includes taxes & fees
2 Nov - 3 Nov
Modern New Mexico Loft in the heart of Las Cruces.
A building entrance with a wooden door, a number '306 4' on the wall, and a doormat with a wreath design.

11. Step into a newly renovated two-bed, one-bath haven in Mesilla Casita Conway #4

Step into a newly renovated two-bed, one-bath haven in Mesilla Casita Conway #4
Las Cruces
10.0 out of 10, Exceptional, (10 reviews)
"Lovely Casita, close to everything, yet has a country feel."
United States
Anonymous traveller
The price is NZ$318
includes taxes & fees
30 Nov - 1 Dec
Step into a newly renovated two-bed, one-bath haven in Mesilla Casita Conway #4
A modern living room with a black leather sofa, patterned cushions, a small round table, a lamp, and a large window with blinds.

12. Cozy and Modern Home w/ King Bed and more!

Cozy and Modern Home w/ King Bed and more!
Las Cruces
9.8 out of 10, Exceptional, (31 reviews)
"We only stayed for a short visit but we had a great time. The Casita is deceptively big with plenty of room to relax. Comfy bed. The Wifi is excellent, too!"
United States
Megan H.
The price is NZ$470
includes taxes & fees
4 Nov - 5 Nov
Cozy and Modern Home w/ King Bed and more!
A kitchen with wooden cabinets, a microwave, a stove, and a tiled backsplash.

13. 2 king bds/2.5 bathrooms in the heart of Downtown

2 king bds/2.5 bathrooms in the heart of Downtown
Las Cruces
10.0 out of 10, Exceptional, (1 review)
"Great communication with host, perfect location centrally located, quiet neighborhood. Beautiful home!"
United States
Veronica M.
2 king bds/2.5 bathrooms in the heart of Downtown
A living room with a fireplace, a sofa, a coffee table, and a ceiling fan.

14. 2 bd/2bth near NMSU and Memorial Medical Center

2 bd/2bth near NMSU and Memorial Medical Center
Las Cruces
10.0 out of 10, Exceptional, (4 reviews)
"Delightful and felt welcome there. All as promoted and responses were totally on point. Location is comforting as well."
United States
Wendy W.
The price is NZ$589
includes taxes & fees
31 Oct - 1 Nov
2 bd/2bth near NMSU and Memorial Medical Center
A hallway with a wooden floor, white walls, and an arched ceiling. There is a dining area with a table and chairs in the distance.

15. Historical 1920s Bungalow Near NMSU & Mesilla

Historical 1920s Bungalow Near NMSU & Mesilla
Las Cruces
10.0 out of 10, Exceptional, (1 review)
"Very clean house and communication with Celeste was good had no problem checking in. Parking on property was great secure and plenty of space. Will definitely be booking again in the future"
United States
Braulio H.
The price is NZ$468
includes taxes & fees
3 Nov - 4 Nov
Historical 1920s Bungalow Near NMSU & Mesilla
A bedroom with a bed, a nightstand, a window with curtains, a wall-mounted picture, and a closet with a hanging rack.

16. The New Zen Den- Cozy Private Studio with Kitchenette & Private Entrance

The New Zen Den- Cozy Private Studio with Kitchenette & Private Entrance
Las Cruces
10.0 out of 10, Exceptional, (2 reviews)
"This space was SPOTLESS, accurate description & everything you needed bundled together! We will definitely book again---Alexis, was easy to work with & helpful! Beautiful location, very accessible, cleanliness, comfortable & affordable."
United States
Jessica R.
The New Zen Den- Cozy Private Studio with Kitchenette & Private Entrance
A neatly made bed with white and blue pillows, a grey headboard, and a blue throw blanket.

17. Payne Place 1

Payne Place 1
Las Cruces
9.4 out of 10, Exceptional, (3 reviews)
"Clean, clean and clean! Great communication "
United States
Diana P.
The price is NZ$427
includes taxes & fees
30 Nov - 1 Dec
Payne Place 1
A kitchen with white cabinets, a black and white checkered floor, a ceiling fan, and a microwave.

18. Hadley House 1 Bed/ 1 Bath Hot Tub 5 min downtown

Hadley House 1 Bed/ 1 Bath Hot Tub 5 min downtown
Las Cruces
Hadley House 1 Bed/ 1 Bath Hot Tub 5 min downtown
A living room with a grey sofa, patterned cushions, a wooden coffee table, and a floral painting on the wall.

19. 2 bed/1 bath near NMSU, pets welcome

2 bed/1 bath near NMSU, pets welcome
Las Cruces
10.0 out of 10, Exceptional, (8 reviews)
"Host was responsive and worked with me to add an additional day after we arrived. Home is so clean and beautiful, was a great place for my family to relax and unwind halfway through our cross country drive. Would love to stay again when I’m in the area"
United States
Jennifer H.
The price is NZ$502
includes taxes & fees
30 Nov - 1 Dec
2 bed/1 bath near NMSU, pets welcome
A modern kitchen with white cabinetry, a central island with stools, a stainless steel refrigerator, and a backsplash with a blue and white pattern.

20. 4 Bedroom Contemporary Model Home

4 Bedroom Contemporary Model Home
Las Cruces
8.8 out of 10, Excellent, (38 reviews)
"Great stay. "
United States
Caroline M.
The price is NZ$443
includes taxes & fees
1 Nov - 2 Nov
4 Bedroom Contemporary Model Home
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Mesilla Hotel Reviews

Casita Azul, Mesilla Plaza Only Steps Away

Casita Azul, Mesilla Plaza Only Steps Away

10/10 Excellent
"We enjoyed our stay at Casita Azul very much. A short walk takes you to the many small shops in Mesilla, cafes, restaurants and the beautiful San Albino Basilica. The casita’s many amenities, including, among other things, a washer and dryer and a very comfortable bed made our 10 night stay very nice. We hope to come for another stay next year."
Vernon S. 10-night trip
Posted 16 hours ago
Casita Azul, Mesilla Plaza Only Steps Away

Find out more about Mesilla

Mesilla Holiday Homes information

Number of reviews
265
Accommodation
191 Holiday Homes
Lowest Price
NZ$289
Highest Price
NZ$653