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Luxury Hotels & Resorts in Melipilla from NZ$89

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Our top choices for Melipilla luxury hotels

Lodge Los Naranjos de Mallarauco

Lodge Los Naranjos de Mallarauco
4.5 star property
Melipilla
The price is NZ$190
14 Jan - 15 Jan 2026
Lodge Los Naranjos de Mallarauco

Hotel Casa Real Viña Santa Rita

Hotel Casa Real Viña Santa Rita
4.0 star property
Buin
9.8 out of 10, Exceptional, (71)
"Everything was amazing. We loved our stay!"
United States
Sandra
The price is NZ$1,172
1 Jan - 2 Jan 2026
Hotel Casa Real Viña Santa Rita

Wyndham Santiago Aeropuerto

Wyndham Santiago Aeropuerto
4.5 star property
Pudahuel
9.0 out of 10, Wonderful, (1154)
"Everything was great !! We loved our stay at this hotel!! Super nice staff and the shuttle service to and from the airport a must !!!"
Australia
Maru
The price is NZ$224
6 Jan - 7 Jan 2026
Wyndham Santiago Aeropuerto

Holiday Inn Santiago - Airport Terminal by IHG

Holiday Inn Santiago - Airport Terminal by IHG
4.0 star property
Pudahuel
9.0 out of 10, Wonderful, (1420)
"Ideal for transit at the airport and service and hotel is very nice. "
United States
MIGUEL
The price is NZ$335
20 Jan - 21 Jan 2026
Holiday Inn Santiago - Airport Terminal by IHG

Casona Lo Aguirre Hotel y Convenciones

Casona Lo Aguirre Hotel y Convenciones
4.0 star property
Talagante
10.0 out of 10, Exceptional, (1)
"muy acogedor y familiar , excelente comunicación y atentos a cualquier requerimiento !!!"
Chile
Jaime
The price is NZ$345
13 Jan - 14 Jan 2026
Casona Lo Aguirre Hotel y Convenciones

Santo Domingo Lodge

Santo Domingo Lodge
5.0 star property
Santo Domingo
7.0 out of 10, Good, (2)
"Property located on top of the cliff. It has good view from the room with hot tub but beside there are nothing, the road condition is very unsafe to drive around so can stay out late, building condition is not good so can hear your next room conversation at all time. "
Canada
Yu-Ji
Santo Domingo Lodge

RQ Santiago

RQ Santiago
4.0 star property
Downtown Santiago
8.6 out of 10, Excellent, (598)
"Good value for the money "
United States
Nina
RQ Santiago
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

Are you searching for the perfect hotel for your luxury trip to Melipilla?
Melipilla has some interesting things to see and do including Vina Chocalan and Kartodromo Las Perdices, so you might want to take in the local sights during your visit.
What's the best luxury accommodation option in Melipilla?
Lodge Los Naranjos de Mallarauco is a luxury lodge with a full-service spa and 2 outdoor pools, and it's a popular choice for Expedia travellers looking for an elegant place to stay.
When can I expect good weather in Melipilla?
Planning for the weather is a good way to make your trip to Melipilla relaxing and enjoyable, especially when you're splurging. The hottest months are usually January and February, with an average temperature of 21°C, while the coldest months are July and August, with an average of 11°C. Average annual precipitation for Melipilla is 401 mm.
What's there to see and do in Melipilla?
Take in some sights and attractions while you're in Melipilla by visiting Vina Chocalan, Casona Los Nogales and Monte Magdalena. If you have a bit of extra time while you're in the area, you might want to check out Matetic Vineyard and Kartodromo Las Perdices.