Matlacha Isles Hotels, Cape Coral

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Check prices for these dates

Tonight
26 Dec - 27 Dec
Tomorrow
27 Dec - 28 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

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Our top choices for Matlacha Isles hotels

Aerial view
DiamondHead Beach Resort

DiamondHead Beach Resort

DiamondHead Beach Resort
3.5 star property
23.5 km from Matlacha Isles
9.0 out of 10, Wonderful, (1006)
"Loved everything about my stay. Staff and service was a 10++"
United States
Jody
DiamondHead Beach Resort
Apartment, Multiple Beds, Partial Ocean View | Beach/ocean view
Edison Beach House

Edison Beach House

Edison Beach House
3.5 star property
22.6 km from Matlacha Isles
9.4 out of 10, Exceptional, (1592)
"Awesome stay "
United States
mary
The price is NZ$403
includes taxes & fees
1 Jan - 2 Jan 2026
Edison Beach House
Exterior
Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers
4.0 star property
23 km from Matlacha Isles
9.0 out of 10, Wonderful, (1730)
"Great place "
United States
Debra Sue
The price is NZ$824
includes taxes & fees
30 Dec - 31 Dec
Margaritaville Beach Resort Fort Myers
Reception
Luminary Hotel & Co., Autograph Collection

Luminary Hotel & Co., Autograph Collection

Luminary Hotel & Co., Autograph Collection
4.0 star property
17.8 km from Matlacha Isles
9.2 out of 10, Wonderful, (482)
"Top floor bar was a great place to get away from things"
United States
Eugene
The price is NZ$422
includes taxes & fees
4 Jan - 5 Jan 2026
Luminary Hotel & Co., Autograph Collection
Bar (on property)
Matanzas Inn Bayside Resort and Marina

Matanzas Inn Bayside Resort and Marina

Matanzas Inn Bayside Resort and Marina
3.0 star property
22.7 km from Matlacha Isles
9.2 out of 10, Wonderful, (1003)
"Rooms were very clean, and the staff was amazing."
United States
Deborah
The price is NZ$326
includes taxes & fees
27 Dec - 28 Dec
Matanzas Inn Bayside Resort and Marina
Outdoor pool, open 8:00 AM to 10:00 PM, pool cabanas (surcharge)
The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village
4.0 star property
Pelican, 12.3 km from Matlacha Isles
9.0 out of 10, Wonderful, (1001)
"Excellent stay over Thanksgiving holiday!"
United States
Nicole
The price is NZ$454
includes taxes & fees
4 Jan - 5 Jan 2026
The Westin Cape Coral Resort At Marina Village
On the beach, white sand, kayaking, motor boating
Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa
4.0 star property
17.2 km from Matlacha Isles
8.4 out of 10, Very good, (1004)
"This was thr best place that we have ever stayed at. "
United States
Matthew
The price is NZ$652
includes taxes & fees
4 Jan - 5 Jan 2026
Marriott Sanibel Harbour Resort & Spa
Property amenity
Crowne Plaza Ft. Myers Gulf Coast by IHG

Crowne Plaza Ft. Myers Gulf Coast by IHG

Crowne Plaza Ft. Myers Gulf Coast by IHG
4.0 star property
30.2 km from Matlacha Isles
9.2 out of 10, Wonderful, (1000)
"Perfectly located, clean and very well run hotel. I came here for a conference was really surprised that the staff was so friendly and the layout was so conducive to me working remotely. I would absolutely come back here."
United States
LUDMILA
The price is NZ$350
includes taxes & fees
30 Dec - 31 Dec
Crowne Plaza Ft. Myers Gulf Coast by IHG
Suite with King Bed, Beachfront, Balcony | Terrace/patio
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

Lani Kai Beachfront Resort
3.5 star property
23.2 km from Matlacha Isles
9.0 out of 10, Wonderful, (1043)
"Clean rooms lovely view of Beach and pool area."
United States
Laurice-Larry
The price is NZ$291
includes taxes & fees
6 Jan - 7 Jan 2026
Lani Kai Beachfront Resort
2 outdoor pools
The Lighthouse Resort Inn & Suites

The Lighthouse Resort Inn & Suites

The Lighthouse Resort Inn & Suites
3.0 star property
22.8 km from Matlacha Isles
8.6 out of 10, Excellent, (1583)
"Great resort fun bar beautiful pool walkable area variety of restaurants and clean beach"
United States
Erika
The Lighthouse Resort Inn & Suites
Outdoor pool
GullWing Beach Resort

GullWing Beach Resort

GullWing Beach Resort
3.5 star property
28.6 km from Matlacha Isles
9.4 out of 10, Exceptional, (932)
"The view of the beach was spectacular. "
United States
Carol
The price is NZ$1,170
includes taxes & fees
9 Jan - 10 Jan 2026
GullWing Beach Resort
Outdoor pool
Casa Ybel Resort

Casa Ybel Resort

Casa Ybel Resort
2.5 star property
24.1 km from Matlacha Isles
8.8 out of 10, Excellent, (290)
"Room was amazing! Their video on their site is pre Hurricane Ian so don’t expect it to be like that ! Lots of devistation but they are working to bring it back. Most staff was nice , the front office staff were snotty and not helpful at !! Location on the beach is amazing! Sanibel / Captiva have captured my heart and I can’t wait to return. I’d stay there again . "
United States
Arra
The price is NZ$992
includes taxes & fees
4 Jan - 5 Jan 2026
Casa Ybel Resort
Luxury Suite, Sea View | Beach/ocean view
Island Inn

Island Inn

Island Inn
3.5 star property
24.3 km from Matlacha Isles
9.4 out of 10, Exceptional, (1123)
"Really nice, updated, and clean room with a screened waterfront balcony in a perfect place on the island (far enough away from the big resorts to be in a quieter area, but close enough to the center area of the island to be convenient). "
United States
Chris
The price is NZ$495
includes taxes & fees
4 Jan - 5 Jan 2026
Island Inn
2 outdoor pools, pool cabanas (surcharge), pool umbrellas
Sundial Beach Resort & Spa

Sundial Beach Resort & Spa

Sundial Beach Resort & Spa
5.0 star property
23.1 km from Matlacha Isles
8.6 out of 10, Excellent, (2584)
"wonderful family friendly and spotless resort"
United States
Mary Anne
The price is NZ$796
includes taxes & fees
25 Jan - 26 Jan 2026
Sundial Beach Resort & Spa
Outdoor pool
Sanibel Island Beach Resort

Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
22.7 km from Matlacha Isles
9.2 out of 10, Wonderful, (1488)
"Excellent value with a great location and a solid staff!"
United States
David
The price is NZ$503
includes taxes & fees
7 Jan - 8 Jan 2026
Sanibel Island Beach Resort
Exterior
Matlacha Tiny Village

Matlacha Tiny Village

Matlacha Tiny Village
3.0 star property
2.5 km from Matlacha Isles
8.8 out of 10, Excellent, (268)
"Very nice place with all necesary accommodations for a Pleasant stay. "
United States
isabel
The price is NZ$368
includes taxes & fees
5 Jan - 6 Jan 2026
Matlacha Tiny Village
Room, 1 King Bed
Boca Grande Hotel

Boca Grande Hotel

Boca Grande Hotel
2.5 star property
28.8 km from Matlacha Isles
8.8 out of 10, Excellent, (585)
"This place was awesome!"
United States
Dharyl
The price is NZ$374
includes taxes & fees
6 Jan - 7 Jan 2026
Boca Grande Hotel
Pool
The Banyan Hotel Fort Myers, Tapestry Collection by Hilton

The Banyan Hotel Fort Myers, Tapestry Collection by Hilton

The Banyan Hotel Fort Myers, Tapestry Collection by Hilton
3.5 star property
17.9 km from Matlacha Isles
8.6 out of 10, Excellent, (844)
"Great location and friendly staff."
United States
Matthew
The price is NZ$339
includes taxes & fees
30 Dec - 31 Dec
The Banyan Hotel Fort Myers, Tapestry Collection by Hilton
In-room safe, desk, laptop workspace, blackout curtains
Shalimar Beach Resort

Shalimar Beach Resort

Shalimar Beach Resort
2.0 star property
24.4 km from Matlacha Isles
10.0 out of 10, Exceptional, (17)
"Everything about this place was great "
United States
Andrew
The price is NZ$859
includes taxes & fees
30 Dec - 31 Dec
Shalimar Beach Resort
Laptop workspace, blackout curtains, free WiFi, bed sheets
StudioRes Fort Myers Airport

StudioRes Fort Myers Airport

StudioRes Fort Myers Airport
3.0 star property
29.5 km from Matlacha Isles
8.8 out of 10, Excellent, (18)
"Clean room, staff, amenities, easy check in, easy access to gas stations, restaurants, and retail. "
United States
Gina
The price is NZ$218
includes taxes & fees
2 Jan - 3 Jan 2026
StudioRes Fort Myers Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our guide on where to stay in Matlacha Isles

Find the best Matlacha Isles areas for the activities you enjoy most.

Pelican

While visiting Pelican, you might make a stop by sights like Tarpon Point and Harbour View Gallery.

Caloosahatchee

If you're spending some time in Caloosahatchee, Cape Coral Yacht Club Beach and Dolphin Marina are top sights worth seeing.

Yacht Club

While Yacht Club isn't home to many top sights, Cape Coral Yacht Club Beach and Dolphin Marina are some notable places to visit nearby.

Hancock

While visiting Hancock, you might make a stop by sights like Four Mile Cove Ecological Preserve and Pine Island Shopping Center.

Mariner

While visiting Mariner, you might make a stop by sights like Mike Greenwell's Bat-A-Ball & Family Fun Park and Yucca Pens Unit State Wildlife Management Area.

Top Matlacha Isles Hotel Reviews

Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

10/10 Excellent
"Perfect "
Aaron 1-night trip
Posted 3 days ago
Lani Kai Beachfront Resort

Frequently asked questions

What is Matlacha Isles like?
Travellers will be sure to find plenty to entertain them in Cape Coral's Matlacha Isles neighbourhood.
How many hotels will I be able to find in the Matlacha Isles area?
When you want to put your feet up after a day of exploring the sights in Cape Coral, you can choose from 17 Expedia hotels and other accommodation options in Matlacha Isles.
If I need to cancel my hotel reservation in Matlacha Isles, will I receive a refund?
Yes, the majority of room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to cancel it and get a refund within a 24-hour period of booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to get the best deals in Matlacha Isles.
What are the top things to see and do in Matlacha Isles?
A few places to visit in the area around Matlacha Isles include Griffen American Center for Haitian Art, Lovegrove Gallery & Gardens and Royal Tee Golf Club. While you're out sightseeing in Cape Coral, make sure that you visit other sights such as Little Dead Key or Big Dead Key.