South Central Houston Hotels, Houston

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Our top choices for South Central Houston hotels

Downtowner Inns - Houston Downtown

Downtowner Inns - Houston Downtown
2.0 star property
South Central Houston
9.2 out of 10, Wonderful, (161 reviews)
"Great place. The staff is very friendly and the place is clean."
United States
Fernando
The price is NZ$185
includes taxes & fees
5 July - 6 July
Downtowner Inns - Houston Downtown

Sentral Forme Houston

Sentral Forme Houston
4.5 star property
South Central Houston
8.8 out of 10, Excellent, (51 reviews)
"Amazing stay!!"
Canada
Elizabeth
The price is NZ$389
includes taxes & fees
12 July - 13 July
Sentral Forme Houston

The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District
4.0 star property
South Central Houston
9.2 out of 10, Wonderful, (1,162 reviews)
"Clean room,restaurant exceptional,excellent staff."
United States
Craig
The price is NZ$318
includes taxes & fees
12 July - 13 July
The Westin Houston Medical Center/Museum District

Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center
4.5 star property
South Central Houston
8.4 out of 10, Very good, (1,970 reviews)
"Great stay and clean room"
United States
Ethel
The price is NZ$261
includes taxes & fees
5 July - 6 July
Hilton Houston Plaza/Medical Center

Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District
4.5 star property
South Central Houston
9.2 out of 10, Wonderful, (1,019 reviews)
"Great place to stay"
United States
Gayathry
The price is NZ$496
includes taxes & fees
12 July - 13 July
Hotel Zaza Houston Museum District

Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District
4.0 star property
South Central Houston
9.0 out of 10, Wonderful, (1,006 reviews)
"This hotel has incredible staff"
United States
Susanne
The price is NZ$378
includes taxes & fees
10 July - 11 July
Houston Marriott Medical Center/Museum District

InterContinental Houston by IHG

InterContinental Houston by IHG
4.0 star property
South Central Houston
9.2 out of 10, Wonderful, (1,018 reviews)
"Great stay, nice staff"
United States
Allen David
The price is NZ$367
includes taxes & fees
5 July - 6 July
InterContinental Houston by IHG

La Maison in Midtown an urban B&B

La Maison in Midtown an urban B&B
3.5 star property
South Central Houston
9.8 out of 10, Exceptional, (577 reviews)
"Beautiful stay with wonderful hosts! Highly recommended!"
Canada
CEDRIC AUGUSTINE DE
The price is NZ$359
includes taxes & fees
6 July - 7 July
La Maison in Midtown an urban B&B

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
3.5 star property
South Central Houston
9.6 out of 10, Exceptional, (214 reviews)
"Beautiful place and wonderful management. Would definitely stay again! "
United States
Shelly
The price is NZ$441
includes taxes & fees
7 July - 8 July
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites
4.0 star property
South Central Houston
8.4 out of 10, Very good, (600 reviews)
"was ok"
United States
Guillermo
The price is NZ$245
includes taxes & fees
5 July - 6 July
DoubleTree by Hilton Houston Medical Center Hotel & Suites

Americas Best Value Inn Medical Center Downtown

Americas Best Value Inn Medical Center Downtown
2.0 star property
South Central Houston
8.0 out of 10, Very good, (1,016 reviews)
"Great AC, Clean room, would stay again"
United States
Haylie
The price is NZ$169
includes taxes & fees
13 July - 14 July
Americas Best Value Inn Medical Center Downtown

Golden Motel Near Houston Medical Center

Golden Motel Near Houston Medical Center
2.5 star property
South Central Houston
2.0 out of 10, (2 reviews)
"Room smelt like cigarettes burnt wholes in the wall and bed sheet all 6 walls had stains toilet seat look like someone stood on it "
United States
Jacari
The price is NZ$141
includes taxes & fees
7 July - 8 July
Golden Motel Near Houston Medical Center

2-bedroom - Equipped Kitchen - Gated Parking

2-bedroom - Equipped Kitchen - Gated Parking
2.0 star property
South Central Houston
The price is NZ$1,100
includes taxes & fees
14 June - 15 June
2-bedroom - Equipped Kitchen - Gated Parking

Hilton University of Houston

Hilton University of Houston
3.5 star property
South Central Houston
9.0 out of 10, Wonderful, (951 reviews)
"The hotel was clean, staff were friendly and the location was perfect for our event. I will definitely stay there again. "
United States
Ricardo
The price is NZ$292
includes taxes & fees
24 June - 25 June
Hilton University of Houston

Southmore Boulevard Motel

Southmore Boulevard Motel
2.0 star property
South Central Houston
5.6 out of 10, (238 reviews)
"I enjoyed my stay at this hotel."
United States
Tamela
The price is NZ$133
includes taxes & fees
15 June - 16 June
Southmore Boulevard Motel

Cozy 2BR Near NRG & Downtown FIFA World Cup

Cozy 2BR Near NRG & Downtown FIFA World Cup
3.0 star property
South Central Houston
The price is NZ$473
includes taxes & fees
14 July - 15 July
Cozy 2BR Near NRG & Downtown FIFA World Cup

Extended Stay America Suites Houston Med Ctr Braeswood Bl

Extended Stay America Suites Houston Med Ctr Braeswood Bl
2.5 star property
South Central Houston
5.8 out of 10, (1,028 reviews)
"Love the pet friendly property"
United States
Nelda
The price is NZ$190
includes taxes & fees
10 July - 11 July
Extended Stay America Suites Houston Med Ctr Braeswood Bl

MorningSide Inn

MorningSide Inn
2.0 star property
South Central Houston
6.0 out of 10, (514 reviews)
"There is no coffeemaker anywhere no schuttel. This place should be razed ."
United States
Barbara
The price is NZ$190
includes taxes & fees
25 June - 26 June
MorningSide Inn

Luxury Med Center Fully Equipped King Sized Bed Condos

Luxury Med Center Fully Equipped King Sized Bed Condos
4.0 star property
South Central Houston
8.4 out of 10, Very good, (92 reviews)
"Facility was nice. DRIFTRS, the management company, is really bad. We were there for 4 days. Upon arrival we noticed no toilet paper and half the light bulbs burned out. The place was so dark I needed a flashlight to use the kitchen. We reported these issues immediately. They told us to use kitchen paper towels as toilet paper and did not respond to all the burned out light bulbs. We woke up every morning with the apartment hot and stuffy. The NEST thermostat is programmed to continually...
United States
Gordon
The price is NZ$443
includes taxes & fees
30 June - 1 July
Luxury Med Center Fully Equipped King Sized Bed Condos

Wanderstay Houston Hostel

Wanderstay Houston Hostel
2.0 star property
South Central Houston
8.2 out of 10, Very good, (204 reviews)
"Excellent stay experience"
United States
Binkeung
The price is NZ$122
includes taxes & fees
6 July - 7 July
Wanderstay Houston Hostel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in South Central Houston

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Exterior
La Maison in Midtown an urban B&B
3.5 star property
9.8
Exceptional
577 reviews
View
Outdoor pool
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
3.5 star property
9.6
Exceptional
214 reviews
View
Laptop workspace, blackout curtains, soundproofing, iron/ironing board
Downtowner Inns - Houston Downtown
2.0 star property
9.2
Wonderful
161 reviews
View
Premium bedding, pillow-top beds, minibar, in-room safe
Hotel Zaza Houston Museum District
4.5 star property
9.2
Wonderful
1,019 reviews
View
Outdoor pool, free pool cabanas, pool umbrellas
The Westin Houston Medical Center/Museum District
4.0 star property
9.2
Wonderful
1,162 reviews
View

Our guide on where to stay in South Central Houston

Find the best South Central Houston areas for the activities you enjoy most. Learn more about South Central Houston
Learn more about South Central Houston

Downtown Houston

Tour the beautiful green spaces, buzzing theater district and professional sports arenas nestled beneath a dramatic cityscape of gleaming skyscrapers.

The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.

Texas Medical Center

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

Montrose

Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.

Top South Central Houston Hotel Reviews

Frequently asked questions

What's it like in South Central Houston?
Travellers are sure to enjoy a stay in Houston's South Central Houston neighbourhood. Make sure that you visit Fertitta Center and Continental Club as part of your South Central Houston travel plans.
What's the best accommodation in South Central Houston?
Based on our traveller data, Hilton Houston Plaza/Medical Center is one of the top choices for your stay in South Central Houston. This hotel is a short 9-minute walk from MD Anderson Cancer Center, and it offers 2 restaurants and 2 bars. Other good options for your stay in the area include Hotel Zaza Houston Museum District and InterContinental Houston by IHG.
How many hotels can I expect to find in the South Central Houston area?
Expedia has 1193 hotels and other accommodation options in South Central Houston to choose from, making this an ideal home base for exploring the greater Houston area.
If I need to cancel my hotel reservation in South Central Houston, will I receive a refund?
Yes! Most room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best deals available in South Central Houston.
What is there to do around this Houston neighbourhood?
Spend some time exploring the great outdoors at Hermann Park, James Turrell's Twilight Epiphany Skyscape and Cullen Sculpture Garden. Fertitta Center and Continental Club are some other stops worth a visit in the neighbourhood. Don't miss favourite places to visit in the surrounding area, such as Toyota Center, Daikin Park and Downtown Aquarium. Shape Community Center and Project Row Houses are also worth a visit when you're out sightseeing in Houston.
How can I get around South Central Houston and the greater Houston area?
For a quick way to explore the city, catch a ride on metro transit at Elgin/Third Ward Station, TSU/UH Athletics District Station or Ensemble/HCC Station. If you want to venture out of town, M. D. Anderson Station is the closest train station. You can also catch a ride at Kinder Station.

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