South Central Houston Hotels: 5,405 Cheap Accommodation in South Central Houston

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Our top choices for South Central Houston hotels

A rooftop patio with outdoor seating, fire pits, and a view of the cityscape.

1. Hilton Houston Plaza/Medical Center

South Central Houston

Cynthia

includes taxes & fees

22 Nov - 23 Nov

A modern hotel room with a large bed, a black leather sofa, a wooden coffee table, and a desk with a mirror.

2. Downtowner Inns - Houston Downtown

South Central Houston

Israel

includes taxes & fees

8 Nov - 9 Nov

A modern hotel building with a prominent entrance, large windows, and a visible name sign.

3. InterContinental Houston by IHG

South Central Houston

Luke

includes taxes & fees

27 Nov - 28 Nov

A rooftop pool area with lounge chairs and a view of a tall building at night.

4. The Westin Houston Medical Center/Museum District

South Central Houston

Leonardo

includes taxes & fees

15 Nov - 16 Nov

A spacious dining area with multiple tables and chairs, large windows, and hanging pendant lights.

5. DoubleTree by Hilton Houston Medical Center Hotel & Suites

South Central Houston

Danny

includes taxes & fees

24 Nov - 25 Nov

A modern restaurant with a bar area, featuring a patterned floor, multiple dining tables, and contemporary lighting fixtures.

6. Houston Marriott Medical Center/Museum District

South Central Houston

Vanessa

includes taxes & fees

22 Nov - 23 Nov

A high-rise hotel with a rooftop pool, multiple floors, and a cityscape view.

7. Sentral Forme Houston

South Central Houston

ebony noelle

includes taxes & fees

1 Dec - 2 Dec

A modern kitchen with dark wood cabinets, a granite countertop, and a built-in island with a glass enclosure.

8. Americas Best Value Inn Medical Center Downtown

South Central Houston

Randy

includes taxes & fees

8 Nov - 9 Nov

A spacious living area with a dining table, chairs, and a chandelier.

9. Hotel Zaza Houston Museum District

South Central Houston

Suzanne

includes taxes & fees

22 Nov - 23 Nov

10. 2824 Aeon Living

South Central Houston

includes taxes & fees

8 Nov - 9 Nov

A spacious lobby with a large sectional sofa, a coffee table, and a reception desk.

11. Hilton University of Houston

South Central Houston

Elizabeth

includes taxes & fees

23 Nov - 24 Nov

A multi-story hotel with a brick facade, balconies, and a well-lit entrance.

12. La Maison in Midtown an urban B&B

South Central Houston

Justin

includes taxes & fees

17 Nov - 18 Nov

A hotel room with a bed, a dining table with chairs, a plant, and a coat rack.

13. 2820 Blodgett St

South Central Houston

includes taxes & fees

20 Nov - 21 Nov

A modern kitchen with a large island, bar stools, and a stainless steel refrigerator.

14. Wanderstay Boutique Hotel

South Central Houston

jennifer k

includes taxes & fees

8 Nov - 9 Nov

A large, multi-story house with a swimming pool, outdoor seating, and a red umbrella.

15. Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

South Central Houston

Walter

includes taxes & fees

18 Nov - 19 Nov

A large outdoor swimming pool with a slide and multiple lanes, surrounded by a modern building with large windows.

16. Fifa Stay 2BR Near NRG DT Med Center -2

South Central Houston

includes taxes & fees

8 Nov - 9 Nov

A hotel room with a bed, a desk, a chair, a mirror, a television, and a heater.

17. Scott Inn Suites - Downtown Houston

South Central Houston

Abdulmuiz

includes taxes & fees

8 Dec - 9 Dec

A hotel room with a bed, bedside table, desk, and a mirror.

18. Southmore Boulevard Motel

South Central Houston

LaKeara

includes taxes & fees

19 Nov - 20 Nov

A spacious lobby with a high ceiling, a central seating area with sofas and armchairs, a staircase leading to an upper level, and a flat-screen TV mounted on the wall.

19. Extended Stay America Suites Houston Med Ctr Braeswood Bl

South Central Houston

Maria Fernanda

includes taxes & fees

8 Dec - 9 Dec

A modern reception area with a blackboard, a blue sofa, a yellow armchair, and a colorful rug.

20. Wanderstay Houston Hostel

South Central Houston

Binkeung

includes taxes & fees

16 Nov - 17 Nov

View all properties

Compare popular hotels in South Central Houston

Property	Property class	Guest rating
Wanderstay Boutique Hotel	3.0 star property	9.8 Exceptional 83 reviews	View
La Maison in Midtown an urban B&B	3.5 star property	9.8 Exceptional 608 reviews	View
Houston Lux Townhome	2.0 star property	9.8 Exceptional 9 reviews	View
InterContinental Houston by IHG	4.0 star property	9.4 Exceptional 1,007 reviews	View
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only	3.5 star property	9.6 Exceptional 221 reviews	View

Our guide on where to stay in South Central Houston

Find the best South Central Houston areas for the activities you enjoy most. Learn more about South Central Houston

Downtown Houston

Tour the beautiful green spaces, buzzing theater district and professional sports arenas nestled beneath a dramatic cityscape of gleaming skyscrapers.

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A tall, modern building with a unique, vertical design, surrounded by trees and a partly cloudy sky.

The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.

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A cityscape with dense high-rise buildings, a river, and surrounding greenery.

Texas Medical Center

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

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A city skyline with modern skyscrapers and a river flowing through a park.

Montrose

Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

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A modern cityscape with a tram and tall buildings.

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.

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Top South Central Houston Hotel Reviews

La Maison in Midtown an urban B&B

South Central Houston

10/10 Excellent

John

Wanderstay Boutique Hotel

South Central Houston

10/10 Excellent

Jennifer

InterContinental Houston by IHG

Texas Medical Center

10/10 Excellent

Anita

Hotel Zaza Houston Museum District

South Central Houston

8/10 Good

Mary

Downtowner Inns - Houston Downtown

Houston Central Business District

10/10 Excellent

Helen

Houston Marriott Medical Center/Museum District

Texas Medical Center

10/10 Excellent

Very safe and secure place to stay as a solo female traveller .. Shuttle to museum district was wonderful !!! Vanessa shuttle driver was very helpful ..The valet said I could use shuttle to get to Galleria but then she said she was no longer allowed to take gusts that far. She helped me find the uber stand . She helped me and went above and beyond with my uber app. Great employee and lovely to talk to. Be aware many uber drivers don’t know where the pick up point is so communicate with them ....

Karen

Hilton University of Houston

Southeast Houston

10/10 Excellent

Karen

Wanderstay Houston Hostel

South Central Houston

8/10 Good

A good hostel, easy to get to buy public bus ($1.25 for each different bus, no transfers for some bizarre reason so take as few as possible, such as route 50 from Hobby airport to Eastwood transit then 25 to block away (Peggy Park). Takes about half an hour to 40 minutes to walk to CBD (downtown). Only issue is there's just two bathrooms for whole hostel and the shower and toilet in the same. Also not a fan of getting sent codes for doors would prefer a key or card.

James

Americas Best Value Inn Medical Center Downtown

Southeast Houston

8/10 Good

Mark

A modern hotel lobby with a fireplace, seating area, and a decorative ceiling.

Homewood Suites by Hilton Houston Memorial

Memorial

10/10 Excellent

Andreas

Frequently Asked Questions

What's it like in South Central Houston?

Travellers are sure to enjoy a stay in Houston's South Central Houston neighbourhood. Make sure that you visit TDECU Stadium and Children's Museum of Houston as part of your South Central Houston travel plans.

What's the best accommodation in South Central Houston?

Based on our traveller data, Hotel Zaza Houston Museum District is one of the top choices for your stay in South Central Houston. This hotel is a short 6-minute walk from Rice University, and it offers a full-service spa and a restaurant. Other good options for your stay in the area include Hilton Houston Plaza/Medical Center and The Westin Houston Medical Center/Museum District.

How many hotels can I expect to find in the South Central Houston area?

Expedia has 1272 hotels and other accommodation options in South Central Houston to choose from, making this an ideal home base for exploring the greater Houston area.

If I need to cancel my hotel reservation in South Central Houston, will I receive a refund?

Yes! Most room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best deals available in South Central Houston.

What is there to do around this Houston neighbourhood?

Spend some time exploring the great outdoors at Hermann Park, Cullen Sculpture Garden and Twilight Epiphany Skyspace. TDECU Stadium and Children's Museum of Houston are some other stops worth a visit in the neighbourhood. Daikin Park and Toyota Center are some popular places to visit in the area around South Central Houston. Shape Community Center and Project Row Houses are also worth a visit when you're out sightseeing in Houston.

How can I get around South Central Houston and the greater Houston area?

For a quick way to explore the city, catch a ride on metro transit at Elgin/Third Ward Station, TSU/UH Athletics District Station or Ensemble/HCC Station. If you want to venture out of town, M. D. Anderson Station is the closest train station. You can also catch a ride at Kinder Station.

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Activities in Houston
Standard Link for Activities in Houston

South Central Houston Hotels, Houston

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for South Central Houston hotels

1. Hilton Houston Plaza/Medical Center

2. Downtowner Inns - Houston Downtown

3. InterContinental Houston by IHG

4. The Westin Houston Medical Center/Museum District

5. DoubleTree by Hilton Houston Medical Center Hotel & Suites

6. Houston Marriott Medical Center/Museum District

7. Sentral Forme Houston

8. Americas Best Value Inn Medical Center Downtown

9. Hotel Zaza Houston Museum District

10. 2824 Aeon Living

11. Hilton University of Houston

12. La Maison in Midtown an urban B&B

13. 2820 Blodgett St

14. Wanderstay Boutique Hotel

15. Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

16. Fifa Stay 2BR Near NRG DT Med Center -2

17. Scott Inn Suites - Downtown Houston

18. Southmore Boulevard Motel

19. Extended Stay America Suites Houston Med Ctr Braeswood Bl

20. Wanderstay Houston Hostel

Compare popular hotels in South Central Houston

Our guide on where to stay in South Central Houston

Downtown Houston

The Galleria

Texas Medical Center

Montrose

Houston Central Business District

Top South Central Houston Hotel Reviews

La Maison in Midtown an urban B&B

10/10 Excellent

Frequently Asked Questions

What's it like in South Central Houston?

What's the best accommodation in South Central Houston?

How many hotels can I expect to find in the South Central Houston area?

If I need to cancel my hotel reservation in South Central Houston, will I receive a refund?

What is there to do around this Houston neighbourhood?

How can I get around South Central Houston and the greater Houston area?

Explore a world of travel with Expedia