Business Hotels & Resorts in Florida Keys

Start date: Check-in selected.
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Florida Keys Business Hotels

Best Florida Keys Business Hotels

Our top choices for Florida Keys business-friendly hotels

Cheeca Lodge & Spa
Private beach, sun-loungers, beach umbrellas, beach towels

Cheeca Lodge & Spa

5.0 star property
9.0 out of 10, Wonderful, (1185)
"Great stay!!!"
The price is NZ$339
includes taxes & fees
16 Sept - 17 Sept
Cheeca Lodge & Spa
Lime Tree Bay Resort
Exterior

Lime Tree Bay Resort

3.5 star property
9.2 out of 10, Wonderful, (1086)
"So close to the ocean was amazing. "
Lime Tree Bay Resort
Hampton Inn Key Largo Manatee Bay
Room, 1 King Bed, Bay View | Beach/ocean view

Hampton Inn Key Largo Manatee Bay

2.5 star property
8.8 out of 10, Excellent, (1009)
"Great friendly place!"
The price is NZ$218
includes taxes & fees
16 Sept - 17 Sept
Hampton Inn Key Largo Manatee Bay
Beacon Hotel South Beach
Courtyard

Beacon Hotel South Beach

3.5 star property
8.0 out of 10, Very good, (2527)
"Great stay!"
The price is NZ$154
includes taxes & fees
9 Sept - 10 Sept
Beacon Hotel South Beach
Islander Resort
Exterior

Islander Resort

4.0 star property
9.2 out of 10, Wonderful, (1005)
"Absolutely wonderful place, great view and staff was outstanding "
The price is NZ$428
includes taxes & fees
16 Sept - 17 Sept
Islander Resort
The Perry Hotel & Marina Key West
2 outdoor pools, open 8:00 AM to 10:00 PM, pool loungers

The Perry Hotel & Marina Key West

4.0 star property
9.4 out of 10, Exceptional, (1091)
"Great rooms awesome service beautiful pool!"
The price is NZ$310
includes taxes & fees
22 Sept - 23 Sept
The Perry Hotel & Marina Key West
Hampton Inn Key West FL
Outdoor pool, pool umbrellas, pool loungers

Hampton Inn Key West FL

2.5 star property
9.0 out of 10, Wonderful, (1231)
"Was an amazing stay"
The price is NZ$307
includes taxes & fees
24 Sept - 25 Sept
Hampton Inn Key West FL
Paradise Inn Key West - Adults Only
Cottage, 2 Bedrooms (Royal Poinciana) | Terrace/patio

Paradise Inn Key West - Adults Only

3.5 star property
9.2 out of 10, Wonderful, (1002)
"Great hotel we have stayed here several times and love it every time. "
Paradise Inn Key West - Adults Only
Bayside Inn Key Largo
Terrace/patio

Bayside Inn Key Largo

3.0 star property
8.6 out of 10, Excellent, (1568)
"Great stay "
The price is NZ$251
includes taxes & fees
10 Sept - 11 Sept
Bayside Inn Key Largo
Parrot Key Hotel & Villas
Waterfront King Guest Room | Exterior

Parrot Key Hotel & Villas

4.0 star property
9.0 out of 10, Wonderful, (1080)
"Great location, very cute resort, huge rooms, would stay again. "
The price is NZ$322
includes taxes & fees
29 Sept - 30 Sept
Parrot Key Hotel & Villas
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Florida Keys Hotel Reviews

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

How much do business-friendly hotels in Florida Keys cost?
Expect to pay between and per night for business-friendly hotels in Florida Keys. Terrific deals on properties that cater to work-related guests are a few clicks away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
How many business-friendly hotels are there in Florida Keys?
When work takes you travelling throughout Florida Keys, there are business-friendly hotels to choose from.
What is there to do in Florida Keys near my business-friendly hotel?
Whether you love dining, sightseeing, museums or malls, Florida Keys has something to suit all tastes! The well-known city of Key West boasts lots of attractions, including Smathers Beach, Fort Zachary Taylor Historic State Park and South Beach. If you're planning a work trip to Key Largo, Jimmy Johnson's Big Chill, Bluefin Rock Harbour Marina and Jacob's Aquatic Centre should be at the top of your to-do list.