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Eastern Panama Holiday Rentals

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Our top choices for Eastern Panama holiday rentals

2.5 star property
The price is NZ$660
includes taxes & fees
30 Dec - 31 Dec
San Blas Private Oceanfront Cabin
2.5 star property
San Blas Private Beach Cabin
2.5 star property
The price is NZ$565
includes taxes & fees
1 Jan - 2 Jan 2026
Private Over-Water Cabins on San Blas Island
2.5 star property
Private Over-the-Water Cabin in San Blas including Meals
2.5 star property
San Blas Secluded Paradise Beach Cabins

Cabin in Narganá

San Blas Tour Aridub
2.0 star property
The price is NZ$426
includes taxes & fees
30 Dec - 31 Dec
San Blas Tour Aridub
10.0 out of 10, Exceptional, (1)
"The beach view was perfect! I loved hearing the waves all day and throughout the night. My dog and I enjoyed everything and felt very comfortable. "
United States
Beth N.
The price is NZ$543
includes taxes & fees
30 Dec - 31 Dec
Caribbean getaway: beach cottage just on the sand

Houseboat in Guna Yala Comarca

Catamaran experience in paradise
The price is NZ$2,055
includes taxes & fees
30 Dec - 31 Dec
Catamaran experience in paradise
The price is NZ$870
includes taxes & fees
8 Jan - 9 Jan 2026
Exclusive sailboat for 2 people all inclusive in San Blas islands

Holiday Home in Colón Province

Cabaña La Punta op het Strand!!
The price is NZ$291
includes taxes & fees
30 Dec - 31 Dec
Cabaña La Punta op het Strand!!
The price is NZ$1,715
includes taxes & fees
5 Jan - 6 Jan 2026
All inclusive 4-bedroom Catamaran up to 8 people in San Blas Panama
The price is NZ$665
includes taxes & fees
30 Dec - 31 Dec
Deluxe Beachfront 4-bedroom house in Colón Province

Holiday Home in Panama , Betania

Private cabin in San Blas
The price is NZ$516
includes taxes & fees
30 Dec - 31 Dec
Private cabin in San Blas

Holiday Home in Garrote

Despierta sobre el mar
2.0 star property
6.0 out of 10, (1)
The price is NZ$184
includes taxes & fees
31 Dec - 1 Jan 2026
Despierta sobre el mar
2.5 star property
8.0 out of 10, Very good, (2)
"I liked the modern payment system that was used for booking the trip, the food was great, the location was as described. I disliked the communication with the reseller this booking goes through. They dropped the ball on communicating pickup time and itinerary confirmation, even when i tried calling and emailing them. I also disliked the value of what you get with this trip. Id expect better cleanliness and standards for this trip. I also disliked when the staff on the island said i needed to pay...
United States
Andrew
San Blas Private Over-the-Water Cabin
10.0 out of 10, Exceptional, (1)
"Great. Please take care of the cat"
United States
KENNETH E.
The price is NZ$119
includes taxes & fees
1 Jan - 2 Jan 2026
Jacuzy, pool and lake at the same house.
The price is NZ$351
includes taxes & fees
5 Jan - 6 Jan 2026
Tranquil cabin with WiFi in Los Altos de Cerro Azul
10.0 out of 10, Exceptional, (1)
"Wir fanden die Unterkunft aufgrund der guten Wegbeschreibung sofort. Die Empfang war sehr nett. Das Haus war sehr sehr sauber und wir haben uns sehr wohl gefühlt. Alles war perfekt. Es war die sauberste/beste Unterkunft die wir bei unserer Panama Rundtour in Panama hatte. Erik und Alba alles Gute und vielen Dank."
Germany
Birgit U.
The price is NZ$250
includes taxes & fees
30 Dec - 31 Dec
Charming cottage with 2 separate beds and a beautiful view of the river

Holiday Home in Panamá

Hummingbird House/Casa de Colibri
The price is NZ$637
includes taxes & fees
1 Jan - 2 Jan 2026
Hummingbird House/Casa de Colibri

Holiday Home in Panamá

Hacienda La Perezosa in Cerro Azul
2.0 star property
The price is NZ$1,705
includes taxes & fees
6 Jan - 7 Jan 2026
Hacienda La Perezosa in Cerro Azul
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Eastern Panama Hotel Reviews

Find out more about Eastern Panama

Everything you need to know about Eastern Panama holiday rentals

Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Eastern Panama holiday rental for you. At Expedia, you can take your pick from private holiday homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Eastern Panama holiday rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

Eastern Panama holiday rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Eastern Panama. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Eastern Panama holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Eastern Panama holiday rentals we have selected for you start as low as NZ$184 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Eastern Panama rentals

At Expedia, we put the best Eastern Panama holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Eastern Panama rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Eastern Panama holiday.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Eastern Panama. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.