A calm sea with a small boat and a row of palm trees on the shore.

Eastern Panama Holiday Rentals

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Our top choices for Eastern Panama holiday rentals

1. san blas luxury tour

san blas luxury tour
2.0 star property
Nusatupo
The price is NZ$257
includes taxes & fees
16 Aug - 17 Aug
san blas luxury tour

2. San Blas Private Oceanfront Cabin

San Blas Private Oceanfront Cabin
2.5 star property
Narganá
The price is NZ$653
includes taxes & fees
18 Aug - 19 Aug
San Blas Private Oceanfront Cabin

3. San Blas Private Over-the-Water Cabin

San Blas Private Over-the-Water Cabin
2.5 star property
Narganá
8.0 out of 10, Very good, (2 reviews)
"I liked the modern payment system that was used for booking the trip, the food was great, the location was as described. I disliked the communication with the reseller this booking goes through. They dropped the ball on communicating pickup time and itinerary confirmation, even when i tried calling and emailing them. I also disliked the value of what you get with this trip. Id expect better cleanliness and standards for this trip. I also disliked when the staff on the island said i needed to pay...
United States
Andrew
The price is NZ$638
includes taxes & fees
17 Aug - 18 Aug
San Blas Private Over-the-Water Cabin

4. Sanblastourgy

Sanblastourgy
2.0 star property
Nargana
The price is NZ$379
includes taxes & fees
16 Aug - 17 Aug
Sanblastourgy

5. Private Over-Water Cabins on San Blas Island

Private Over-Water Cabins on San Blas Island
2.5 star property
Narganá
The price is NZ$560
includes taxes & fees
16 Aug - 17 Aug
Private Over-Water Cabins on San Blas Island

6. Private Over-the-Water Cabin in San Blas including Meals

Private Over-the-Water Cabin in San Blas including Meals
2.5 star property
Mirladub
The price is NZ$908
includes taxes & fees
18 Aug - 19 Aug
Private Over-the-Water Cabin in San Blas including Meals

7. San Blas Tour Aridub

San Blas Tour Aridub
2.0 star property
Narganá
The price is NZ$244
includes taxes & fees
16 Aug - 17 Aug
San Blas Tour Aridub

8. All inclusive 4-bedroom Catamaran up to 8 people in San Blas Panama

All inclusive 4-bedroom Catamaran up to 8 people in San Blas Panama
Guna Yala Comarca
The price is NZ$1,469
includes taxes & fees
14 Sept - 15 Sept
All inclusive 4-bedroom Catamaran up to 8 people in San Blas Panama

9. Lovely Caribbean Apartment with AC + Wifi + BBQ + Beach + Kitchen + Parking

Lovely Caribbean Apartment with AC + Wifi + BBQ + Beach + Kitchen + Parking
Puerto Lindo
The price is NZ$433
includes taxes & fees
16 Aug - 17 Aug
Lovely Caribbean Apartment with AC + Wifi + BBQ + Beach + Kitchen + Parking

10. San Blas Private Beach Cabin

San Blas Private Beach Cabin
2.5 star property
Narganá
The price is NZ$501
includes taxes & fees
17 Aug - 18 Aug
San Blas Private Beach Cabin

11. Deluxe Beachfront 4-bedroom house in Colón Province

Deluxe Beachfront 4-bedroom house in Colón Province
Colón Province
The price is NZ$650
includes taxes & fees
16 Aug - 17 Aug
Deluxe Beachfront 4-bedroom house in Colón Province

12. escondidapanama | 404B | 12ppl | 7 beds | 5BR/5BA

escondidapanama | 404B | 12ppl | 7 beds | 5BR/5BA
Maria Chiquita
The price is NZ$963
includes taxes & fees
31 Aug - 1 Sept
escondidapanama | 404B | 12ppl | 7 beds | 5BR/5BA

13. Jacuzy, pool and lake at the same house.

Jacuzy, pool and lake at the same house.
Colon
7.4 out of 10, Good, (3 reviews)
"Great. Please take care of the cat"
United States
KENNETH E.
The price is NZ$117
includes taxes & fees
17 Aug - 18 Aug
Jacuzy, pool and lake at the same house.

14. Hacienda La Perezosa in Cerro Azul

Hacienda La Perezosa in Cerro Azul
Panamá
The price is NZ$1,678
includes taxes & fees
17 Aug - 18 Aug
Hacienda La Perezosa in Cerro Azul

15. BEAUTIFUL APARTMENT IN FRONT OF THE SEA

BEAUTIFUL APARTMENT IN FRONT OF THE SEA
Portobelo
7.0 out of 10, Good, (4 reviews)
"All of it! Gabriel is a marvelous host; absolutely above and beyond. The house is lovely, very unique, and the location, right on the water, superb. We'll be back!"
United States
Rosa M.
The price is NZ$300
includes taxes & fees
17 Aug - 18 Aug
BEAUTIFUL APARTMENT IN FRONT OF THE SEA

16. La Husseyenda. Private Birdwatching Retreat in Cerro Azul’s Mountains in Panama

La Husseyenda. Private Birdwatching Retreat in Cerro Azul’s Mountains in Panama
Panamá
The price is NZ$470
includes taxes & fees
16 Aug - 17 Aug
La Husseyenda. Private Birdwatching Retreat in Cerro Azul’s Mountains in Panama

17. Hummingbird House/Casa de Colibri

Hummingbird House/Casa de Colibri
Panamá
The price is NZ$536
includes taxes & fees
17 Aug - 18 Aug
Hummingbird House/Casa de Colibri

18. Your Menus de la Montaña country house awaits you

Your Menus de la Montaña country house awaits you
Panama
The price is NZ$387
includes taxes & fees
16 Aug - 17 Aug
Your Menus de la Montaña country house awaits you

19. Beautiful 2-bedroom apartment in Cerro Azul for your jungle getaway

Beautiful 2-bedroom apartment in Cerro Azul for your jungle getaway
Panamá
The price is NZ$238
includes taxes & fees
16 Aug - 17 Aug
Beautiful 2-bedroom apartment in Cerro Azul for your jungle getaway

20. Elegance and comfort in old town panama

Elegance and comfort in old town panama
Panamá
2.0 out of 10, (1 review)
"The address that’s depicted is not accurate to the map that’s shown and I tried multiple times to communicate with the host and no response"
United States
PAMELA
The price is NZ$153
includes taxes & fees
20 Aug - 21 Aug
Elegance and comfort in old town panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Eastern Panama Hotel Reviews

Find out more about Eastern Panama

You always said you would go on a dream holiday someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannonball into the deep end. Go ahead, unplug and unwind in style. When you book one of our Eastern Panama holiday rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your holiday just got upgraded.

As much as you love your vacation rental, it’s always good to get out and explore to soak up Eastern Panama. Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in Eastern Panama. Seeing all the best attractions is bound to make you fall in love with Eastern Panama. Who knows, you may even be tempted to extend your stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true. 

It’s your escape so why share it? You deserve your own slice of paradise. Booking your holiday rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in Eastern Panama short-term rentals, that won’t be hard to do.