Downtown Clayton Hotels, St. Louis

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Our top choices for Downtown Clayton hotels

Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton
4.0 star property
Downtown Clayton
8.8 out of 10, Excellent, (704 reviews)
"Clean room & good included breakfast "
United Kingdom
Felix
The price is NZ$295
includes taxes & fees
3 Apr - 4 Apr
Le Méridien St. Louis Clayton

AC Hotel St. Louis Clayton

AC Hotel St. Louis Clayton
3.0 star property
Downtown Clayton
9.0 out of 10, Wonderful, (268 reviews)
"Great location"
United States
Rolando
The price is NZ$292
includes taxes & fees
19 Apr - 20 Apr
AC Hotel St. Louis Clayton

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay
3.5 star property
Downtown Clayton
8.8 out of 10, Excellent, (3,137 reviews)
"Wonderful breakfast, easy and safe parking, comfortable beds, great shower!"
United States
Amy M.
The price is NZ$204
includes taxes & fees
19 Apr - 20 Apr
Clayton Plaza Hotel & Extended Stay

The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
5.0 star property
Downtown Clayton
9.2 out of 10, Wonderful, (562 reviews)
"Excellent hotel with various restaurants and expansive lobby area.. staff very attentive."
United States
Diane M
The price is NZ$1,014
includes taxes & fees
19 Apr - 20 Apr
The Ritz-Carlton, St. Louis

Seven Gables, St. Louis West, a Tribute Portfolio Hotel

Seven Gables, St. Louis West, a Tribute Portfolio Hotel
3.5 star property
Downtown Clayton
8.4 out of 10, Very good, (586 reviews)
"Rooms were very clean and the staff was friendly!"
United States
Deanna
The price is NZ$301
includes taxes & fees
4 Apr - 5 Apr
Seven Gables, St. Louis West, a Tribute Portfolio Hotel

Hyatt Select St. Louis Airport

Hyatt Select St. Louis Airport
2.5 star property
9.7 km from Downtown Clayton
9.2 out of 10, Wonderful, (1,003 reviews)
"The staff was friendly, pool hours were great and breakfast was satisfying "
United States
Charles
The price is NZ$235
includes taxes & fees
13 Apr - 14 Apr
Hyatt Select St. Louis Airport

Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport
2.5 star property
10.4 km from Downtown Clayton
9.2 out of 10, Wonderful, (1,570 reviews)
"Great location room was nice and clean "
United States
Gabriela
The price is NZ$223
includes taxes & fees
5 Apr - 6 Apr
Wingate by Wyndham St. Louis Airport

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
2.5 star property
10.4 km from Downtown Clayton
9.4 out of 10, Exceptional, (2,891 reviews)
"Great stay, super clean and friendly staff."
United States
Edmarie
The price is NZ$185
includes taxes & fees
13 Apr - 14 Apr
Pear Tree Inn St. Louis Airport

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
14.7 km from Downtown Clayton
9.0 out of 10, Wonderful, (1,507 reviews)
"Great place with lots of restaurants "
United States
Dennis
The price is NZ$219
includes taxes & fees
14 Apr - 15 Apr
River City Casino & Hotel

Drury Inn & Suites St. Louis Airport

Drury Inn & Suites St. Louis Airport
3.0 star property
10.1 km from Downtown Clayton
9.2 out of 10, Wonderful, (1,165 reviews)
"Great stay! Clean and food was great "
United States
Mary
The price is NZ$235
includes taxes & fees
13 Apr - 14 Apr
Drury Inn & Suites St. Louis Airport

Motel 6 Hazelwood, MO

Motel 6 Hazelwood, MO
2.0 star property
14.6 km from Downtown Clayton
8.6 out of 10, Excellent, (1,896 reviews)
"Great place to stay"
United States
Kerry
The price is NZ$139
includes taxes & fees
15 Apr - 16 Apr
Motel 6 Hazelwood, MO

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis, 13.1 km from Downtown Clayton
9.4 out of 10, Exceptional, (3,358 reviews)
"Great location and breakfast "
United States
Jenny
The price is NZ$331
includes taxes & fees
12 Apr - 13 Apr
Drury Plaza Hotel St. Louis at the Arch

Hampton Inn & Suites St. Louis at Forest Park

Hampton Inn & Suites St. Louis at Forest Park
2.5 star property
Dogtown, 5.3 km from Downtown Clayton
9.4 out of 10, Exceptional, (1,008 reviews)
"Great stay, great location"
United States
Michelle
The price is NZ$252
includes taxes & fees
12 Apr - 13 Apr
Hampton Inn & Suites St. Louis at Forest Park

Drury Inn & Suites St. Louis St. Peters

Drury Inn & Suites St. Louis St. Peters
3.0 star property
29.6 km from Downtown Clayton
9.4 out of 10, Exceptional, (1,008 reviews)
"Great stay! Very clean and staff was very nice. Definitely will be staying there on my return visit to the area!"
United States
Roxanne
The price is NZ$220
includes taxes & fees
19 Apr - 20 Apr
Drury Inn & Suites St. Louis St. Peters

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
16.4 km from Downtown Clayton
8.0 out of 10, Very good, (1,174 reviews)
"Everything was great for overnight stay. "
United States
Regina
The price is NZ$180
includes taxes & fees
5 Apr - 6 Apr
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Courtyard by Marriott St. Louis St. Peters

Courtyard by Marriott St. Louis St. Peters
3.0 star property
26.6 km from Downtown Clayton
9.0 out of 10, Wonderful, (697 reviews)
"Clean room, friendly staff "
United States
DeSondra
The price is NZ$242
includes taxes & fees
12 Apr - 13 Apr
Courtyard by Marriott St. Louis St. Peters

Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel
4.0 star property
Berkeley, 9.3 km from Downtown Clayton
8.4 out of 10, Very good, (1,069 reviews)
"Great place to stay "
United States
Timothy
The price is NZ$260
includes taxes & fees
11 Apr - 12 Apr
Renaissance St. Louis Airport Hotel

Holiday Inn Express & Suites St. Louis South - I-55 by IHG

Holiday Inn Express & Suites St. Louis South - I-55 by IHG
2.5 star property
18.4 km from Downtown Clayton
9.6 out of 10, Exceptional, (1,004 reviews)
"Clean room, friendly staff. "
United States
Jamie
The price is NZ$236
includes taxes & fees
5 Apr - 6 Apr
Holiday Inn Express & Suites St. Louis South - I-55 by IHG

Wingate by Wyndham St. Louis/Fenton Route 66

Wingate by Wyndham St. Louis/Fenton Route 66
3.0 star property
16.5 km from Downtown Clayton
7.8 out of 10, Good, (1,180 reviews)
"Great location, comfy and clean rooms "
United States
Nestor
The price is NZ$171
includes taxes & fees
13 Apr - 14 Apr
Wingate by Wyndham St. Louis/Fenton Route 66

Pear Tree Inn St. Louis Arnold

Pear Tree Inn St. Louis Arnold
2.5 star property
23.1 km from Downtown Clayton
9.4 out of 10, Exceptional, (1,000 reviews)
"Will definitely stay here again! "
United States
Sharon
The price is NZ$181
includes taxes & fees
4 Apr - 5 Apr
Pear Tree Inn St. Louis Arnold
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our guide on where to stay in Downtown Clayton

Find the best Downtown Clayton areas for the activities you enjoy most.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Busch Stadium – discover Downtown St. Louis, a destination also famous for its historic sites.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

Downtown West

While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and Enterprise Center.

Berkeley

Visitors highly recommend Berkeley for its abundant dining options, and you can make a stop by James S. McDonnell Prologue Room while you're in town.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

Top Downtown Clayton Hotel Reviews

Frequently asked questions

What's it like in Downtown Clayton?
Travellers to the Downtown Clayton neighbourhood in St. Louis will be sure to enjoy their stay.
What's a favourite hotel to stay in Downtown Clayton?
Based on Expedia customer reviews, AC Hotel St. Louis Clayton is the highest ranked property in Downtown Clayton. This hotel offers 2 restaurants and 2 bars. Other favourite options in the area include The Ritz-Carlton, St. Louis and Clayton Plaza Hotel & Extended Stay.
How many hotels can I expect to find in the Downtown Clayton area?
Expedia has 6 Downtown Clayton hotels and other accommodation options, and one might make a good home base for venturing out into the greater St. Louis area.
If I need to cancel my hotel reservation in Downtown Clayton, will I receive a refund?
Yes! Most hotel room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If your reservation is non-refundable, it might still be possible to cancel it and receive a refund within a 24-hour period of booking. Add dates, click "Search", then you can filter by "fully refundable" to get the top deals on offer in Downtown Clayton.
What can I see and do in this St. Louis neighbourhood?
St. Louis Zoo, Shaw Park Tennis Center and Saint Louis Galleria Mall are just a few of the places to visit in and around Downtown Clayton. While you're out sightseeing, Tao Tennis Center and Center of Creative Arts are a couple of additional sights to visit in St. Louis.
How can I get around Downtown Clayton and the greater St. Louis area?
Ready to get out and explore the city? Clayton Station is the closest metro station.