Centro Histórico Holidays

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Our guide on where to stay in Centro Histórico

Find the best Centro Histórico areas and neighborhoods for the activities you enjoy most. Learn more about Centro Histórico
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Equipetrol

When in Equipetrol, you can plan a visit to Santa Cruz Zoo and Municipal Library, some noteworthy sights in the nearby area.

Find hotels in Equipetrol

Our pick of the best Centro Histórico Hotel Deals

Lido Hotel

Lido Hotel

3 out of 5
Calle 21 de Mayo 527 Santa Cruz
The price is NZ$39 per night from 18 Nov to 19 Nov
NZ$39
18 Nov - 19 Nov
Lido Hotel
Hotel Las Américas

Hotel Las Américas

3 out of 5
Calle 21 de Mayo esq, Seoane N 356 Santa Cruz Santa Cruz Department
Fully refundableReserve now, pay when you stay
The price is NZ$41 per night from 8 Nov to 9 Nov
NZ$41
8 Nov - 9 Nov
8/10 Very good! (35 reviews)
"Great place for the price. Only issue I had was the music blaring one of two nights across the street - all night, from 9pm to 6am. Not the hotels fault; but frustrating. Would stay again though"

Reviewed on 22 Oct 2026

Hotel Las Américas
Cosmopolitano Hotel Boutique

Cosmopolitano Hotel Boutique

3.5 out of 5
Pari, 70 Santa Cruz
The price is NZ$95 per night from 8 Nov to 9 Nov
NZ$95
8 Nov - 9 Nov
9.2/10 Wonderful! (140 reviews)
"This is a lovely hotel in a quiet location but very close to the main plaza. There is a great hamburger cafe opposite which serves fresh delicious food and cold beer. The stand out for this hotel is the staff who are friendly and helpful."

Reviewed on 28 Oct 2026

Cosmopolitano Hotel Boutique
See all 316 properties in Centro Histórico
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Centro Histórico attractions

A historic building with arched windows and a clock. People are sitting and standing on the steps in front of the building.

Plaza 24 de Septiembre

8.8/10 (164 reviews)
The heart of Santa Cruz lies in this public square, where locals relax and tourists sightsee in a welcoming, laid-back atmosphere.
See properties

Activities

Santa Cruz: Wildlife Sanctuary and Preservation Park Tour

Santa Cruz: Wildlife Sanctuary and Preservation Park Tour

NZ$152
per adult
Santa Cruz: Wildlife Sanctuary and Preservation Park Tour
Samaipata Fort, Bolivia

Samaipata Fort Tour: Ancient Ruins in 1 Full Day

NZ$731
per adult
Samaipata Fort Tour: Ancient Ruins in 1 Full Day
Historical trekking in the Churo Quebrada, La Higuera. In this thick vegetation of Vallegrande, we travel the scene of Ernesto "Che" Guevara's last fight in 1967.

3D/2N Getaway on the Che Guevara Route Live the Adventure!

NZ$1,462
per adult
3D/2N Getaway on the Che Guevara Route Live the Adventure!
See all activities in Santa Cruz
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.