A large white dome building with a red brick base, surrounded by green trees and a clear blue sky.

Spa Hotels & Resorts in Central Missouri from NZ$165

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Central Missouri Spa Hotels

Tonight
14 Oct - 15 Oct
Tomorrow
15 Oct - 16 Oct
This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

Our top choices for Central Missouri hotels with a spa

A hotel room with two beds, a nightstand, a cabinet, and a wall-mounted artwork.
A marina with docks and a large hotel building in the background.
A poolside area with stone walls and a bar.
An aerial view of a marina at dusk with illuminated buildings, docks, and boats.

1. Camden on the Lake Resort & Spa

Camden on the Lake Resort & Spa
Lake Ozark
  • Relax at this lakeside resort with four treatment rooms at Spa 54, featuring hot stone massages, hydrotherapy, and couples' services.
NZ$238
includes taxes & fees
1 Nov - 2 Nov
Camden on the Lake Resort & Spa
A lakeside bar named "FIRE ICE" with outdoor seating and a view of the lake.
A spacious lobby with a high ceiling, stone accents, and a central fireplace.
A large indoor swimming pool with clear water, surrounded by large windows offering views of greenery and a stone building.
An outdoor seating area with a fire pit, chairs, and a view of a lake at sunset.

2. Lodge Of Four Seasons Golf Resort, Marina & Spa

Lodge Of Four Seasons Golf Resort, Marina & Spa
Lake Ozark
  • Luxurious lakeside retreat with rejuvenating spa treatments and tranquil Japanese gardens for ultimate relaxation.
NZ$231
includes taxes & fees
1 Nov - 2 Nov
Lodge Of Four Seasons Golf Resort, Marina & Spa
A thatched-roof building with a sign reading "TIKI HUT POOL BAR".
Two people sitting on green Adirondack chairs facing a body of water with a forested shoreline in the background.
A deck with a view of a lake, dock, and chairs.
A spacious lobby with a stone fireplace, comfortable seating, and a large mural on the ceiling.

3. Margaritaville Lake Resort Lake of the Ozarks

Margaritaville Lake Resort Lake of the Ozarks
Osage Beach
  • Lakeside spa resort with golf course offers rejuvenating massages, body treatments, and poolside relaxation.
NZ$312
includes taxes & fees
1 Nov - 2 Nov
Margaritaville Lake Resort Lake of the Ozarks
A bar area with wooden counters and stone accents, a stone wall, and a wooden door.
A stone gazebo with a stone pathway leading to it, surrounded by well-maintained grass and a pond.
A golf course with a swimming pool and a clubhouse.
A balcony with two chairs and a table, overlooking a golf course and a lake.

4. The Lodge at Old Kinderhook Golf Resort

The Lodge at Old Kinderhook Golf Resort
Camdenton
  • Revitalise at this lakeside retreat with full-service spa, golf course, and dual pools for ultimate relaxation.
NZ$285
includes taxes & fees
26 Oct - 27 Oct
The Lodge at Old Kinderhook Golf Resort
A room with a bed, a desk with a computer, and a shelf with toiletries.
A dining area with a large wooden table and ornate chairs, a ceiling fan, and framed artwork on the walls.
A room with a large window, a ceiling fan, a sofa, a table with chairs, and a lamp.
A bar area with a polished wooden counter, a flat-screen TV mounted on the wall, and a framed picture above the counter.

5. The Courtland Hotel and Day Spa

The Courtland Hotel and Day Spa
Fort Scott
  • Tranquil historic hotel offers rejuvenating spa escape with four serene treatment rooms for ultimate relaxation.
NZ$165
includes taxes & fees
18 Oct - 19 Oct
The Courtland Hotel and Day Spa
A spa area with a massage table, a hot tub, and a grill.
A hot tub with a view of a forest, a bath brush, and a robe hanging on the wall.
A hot tub, a fire pit, and a view of a lake.
A living room with a fireplace, a dining area with a round table, and a balcony with a view.

6. Hermann Hill

Hermann Hill
Hermann
  • Riverside bed and breakfast with private spa pools and spa treatments offers romantic rejuvenation.
NZ$635
includes taxes & fees
2 Nov - 3 Nov
Hermann Hill
View all properties

Choose what matters most at spa hotels in Central Missouri

Pool
Breakfast included
Spa pool
4 stars
5 stars

Top Central Missouri Hotel Reviews

Stoney Creek Hotel Columbia

Stoney Creek Hotel Columbia

10/10 Excellent
"Spacious, comfortable room. Love the free shuttle to the stadium. Highly recommend!"
SID 2-night trip
Posted 13 hours ago
Stoney Creek Hotel Columbia
Country Inn & Suites by Radisson, Columbia, MO

Country Inn & Suites by Radisson, Columbia, MO

10/10 Excellent
"I was pleased with the quality of the room overall and the breakfast was very good. The rate was excellent for service received and we plan to return. Be aware that mizzou home football games will elevate the rates markedly beyond what I would accept. At other times, the value is among the best in town."
Carlos 2-night trip
Posted 18 hours ago
Country Inn & Suites by Radisson, Columbia, MO
Margaritaville Lake Resort Lake of the Ozarks

Margaritaville Lake Resort Lake of the Ozarks

10/10 Excellent
"Okay stay."
DARIA 2-night trip
Posted 2 days ago
Margaritaville Lake Resort Lake of the Ozarks
Inn at Grand Glaize

Inn at Grand Glaize

8/10 Good
"Enjoyable stay!"
Brian 1-night trip
Posted 6 days ago
Inn at Grand Glaize

Explore a world of travel with Expedia