Top Hotels Near Casa Santo Domingo Museum in Antigua Guatemala from NZ$36

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Our top choices for Casa Santo Domingo Museum hotels

Las Cruces Boutique Hotel

Las Cruces Boutique Hotel
4.0 star property
Historic Center, 0.5 km from Casa Santo Domingo Museum
9.8 out of 10, Exceptional, (222)
"Great place!"
United States
Ragnar
The price is NZ$525
includes taxes & fees
17 Dec - 18 Dec
Las Cruces Boutique Hotel

Hostal Antigueño - Hostel

Hostal Antigueño - Hostel
2.0 star property
0.3 km from Casa Santo Domingo Museum
9.2 out of 10, Wonderful, (30)
"Great place, great people! Highly recommend!"
Canada
Cody
The price is NZ$99
includes taxes & fees
31 Dec - 1 Jan 2026
Hostal Antigueño - Hostel

El Convento Boutique Hotel

El Convento Boutique Hotel
4.0 star property
Historic Center, 0.4 km from Casa Santo Domingo Museum
9.4 out of 10, Exceptional, (803)
"Great hotel to explore Antigua "
United States
vered
The price is NZ$327
includes taxes & fees
17 Dec - 18 Dec
El Convento Boutique Hotel

Hotel Camino Real Antigua

Hotel Camino Real Antigua
4.0 star property
Historic Center, 1 km from Casa Santo Domingo Museum
9.6 out of 10, Exceptional, (1006)
"Amazing hotel with beautiful gardens, great rooms, helpful staff and the top breakfast in Antigua. "
United States
Audrey
The price is NZ$465
includes taxes & fees
12 Jan - 13 Jan 2026
Hotel Camino Real Antigua

Las Camelias Inn

Las Camelias Inn
3.0 star property
Historic Center, 0.3 km from Casa Santo Domingo Museum
8.8 out of 10, Excellent, (578)
"Very good place for my stay in Antigua. They were so helpful in storing my luggages away even after check out for a whole day for free when I went for the volcano hike. "
Canada
Joel
The price is NZ$177
includes taxes & fees
7 Jan - 8 Jan 2026
Las Camelias Inn

Hotel Las Farolas

Hotel Las Farolas
3.5 star property
1 km from Casa Santo Domingo Museum
9.2 out of 10, Wonderful, (702)
"It is relatively close and walkable to the central plaza and all amenities around it."
United States
helmuth
The price is NZ$231
includes taxes & fees
5 Jan - 6 Jan 2026
Hotel Las Farolas

Sonnenhaus

Sonnenhaus
2.0 star property
Barrio de La Concepción, < 0.1 km from Casa Santo Domingo Museum
8.4 out of 10, Very good, (11)
"Overall good just keep in mind shared restrooms and kitchen but great price and safe "
United States
edwin
The price is NZ$67
includes taxes & fees
23 Dec - 24 Dec
Sonnenhaus

La Villa Serena

La Villa Serena
3.0 star property
1.5 km from Casa Santo Domingo Museum
9.6 out of 10, Exceptional, (109)
"room was very pretty and bed was extremely comfortable. "
United States
clara
The price is NZ$167
includes taxes & fees
17 Dec - 18 Dec
La Villa Serena

Hotel Casa Anturio

Hotel Casa Anturio
3.0 star property
Historic Center, 0.9 km from Casa Santo Domingo Museum
9.2 out of 10, Wonderful, (49)
"Great place "
United States
Charles
The price is NZ$120
includes taxes & fees
17 Dec - 18 Dec
Hotel Casa Anturio

Hotel La Posadita Antigua

Hotel La Posadita Antigua
3.0 star property
1 km from Casa Santo Domingo Museum
8.8 out of 10, Excellent, (38)
"Location and friendly staff"
United States
Jose Alejandro
Hotel La Posadita Antigua

Casa Quetzalli Los Nazarenos

Casa Quetzalli Los Nazarenos
2.0 star property
1.3 km from Casa Santo Domingo Museum
9.4 out of 10, Exceptional, (24)
"The room was very clean and large. I stayed in room 1 and the car noises were very present but after a day of hiking it was not hard to fall asleep."
United States
Tina
The price is NZ$72
includes taxes & fees
3 Jan - 4 Jan 2026
Casa Quetzalli Los Nazarenos

All Suite El Marques de Antigua

All Suite El Marques de Antigua
3.5 star property
0.9 km from Casa Santo Domingo Museum
9.2 out of 10, Wonderful, (300)
"The staff was courteous and all amenities were in place. "
United States
Debra
All Suite El Marques de Antigua

Casa Buho B&B

Casa Buho B&B
3.0 star property
Santa Ana, 1.3 km from Casa Santo Domingo Museum
9.2 out of 10, Wonderful, (48)
"Great place !!"
United States
Abner Israel Polanco
The price is NZ$138
includes taxes & fees
8 Jan - 9 Jan 2026
Casa Buho B&B

Yellow House - Hostel

Yellow House - Hostel
2.0 star property
Historic Center, 1 km from Casa Santo Domingo Museum
9.2 out of 10, Wonderful, (292)
"Had a really pleasant stay here. The staff were very warm and welcoming and went out of their way to help us book onward travel. Stayed in the private room with en-suite bathroom and it was perfect for our needs. Quiet and peaceful at night, comfortable bed, nice hot shower. Ideal!"
United States
Daniel
The price is NZ$74
includes taxes & fees
23 Dec - 24 Dec
Yellow House - Hostel

Hotel Las Marías

Hotel Las Marías
3.0 star property
1.4 km from Casa Santo Domingo Museum
9.2 out of 10, Wonderful, (432)
"The room and and entire property was really nice and well put together. The staff was super friendly and the breakfast provided was fantastic. Highly recommend. "
United States
Ilhaan
The price is NZ$200
includes taxes & fees
1 Jan - 2 Jan 2026
Hotel Las Marías

Posada el Antaño

Posada el Antaño
3.0 star property
Historic Center, 0.8 km from Casa Santo Domingo Museum
8.8 out of 10, Excellent, (71)
"Location"
Mexico
Gloria
The price is NZ$205
includes taxes & fees
7 Jan - 8 Jan 2026
Posada el Antaño

Cermeños House

Cermeños House
2.0 star property
Historic Center, 1 km from Casa Santo Domingo Museum
8.6 out of 10, Excellent, (31)
"Elizabeth and the staff will treat you like family-a wonderful place!"
United States
LESLIE
The price is NZ$80
includes taxes & fees
9 Jan - 10 Jan 2026
Cermeños House

Socialtel Antigua

Socialtel Antigua
3.0 star property
0.9 km from Casa Santo Domingo Museum
8.6 out of 10, Excellent, (109)
"Great value and comfortable room with nice view. "
United States
William
The price is NZ$130
includes taxes & fees
17 Dec - 18 Dec
Socialtel Antigua

Hostal Casa Buho

Hostal Casa Buho
3.0 star property
Santa Ana, 1.3 km from Casa Santo Domingo Museum
8.6 out of 10, Excellent, (21)
"Nice clean affordable accomodations and very accomodating and amicable hosts."
United States
Feng
The price is NZ$100
includes taxes & fees
5 Jan - 6 Jan 2026
Hostal Casa Buho

Casa Realeza

Casa Realeza
3.0 star property
Historic Center, 0.6 km from Casa Santo Domingo Museum
8.2 out of 10, Very good, (80)
"Only better breakfast otherwise it’s a good stay thanks "
United States
Jorge Luis
Casa Realeza
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Casa Santo Domingo Museum Hotel Reviews

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Frequently asked questions

What's the area like around Casa Santo Domingo Museum?
Casa Santo Domingo Museum is located in a historic area of Antigua Guatemala known for its major shopping area. If you're looking for a convenient place to stay, take a look at the 497 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay close to Casa Santo Domingo Museum?
Adjacent to Casa Santo Domingo Museum, Hotel Museo Spa Casa Santo Domingo is one of the top choices for your stay based on our traveller data, and this hotel offers a full-service spa and 2 restaurants. Other good choices close by include Porta Hotel Antigua and Hotel Camino Real Antigua.
How many hotels are there near Casa Santo Domingo Museum?
Expedia has 497 hotels and other accommodation options within a mile from Casa Santo Domingo Museum.
If I need to cancel the hotel reservation for my stay near Casa Santo Domingo Museum, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to review the best deals available near Casa Santo Domingo Museum.
What can I see and do near Casa Santo Domingo Museum?
You might want to spend some time browsing the exhibits at Antigua Guatemala Colonial Art Museum, Jade Maya Factory and Museum or La Azotea Cultural Center. Explore notable local landmarks like Las Capuchinas Convent, Santa Clara Convent and Santa Catalina Arch. Spend some time exploring the the natural beauty of Central Park, Tanque La Unión and El Reposo Spa.