Search Florence hotels

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
7 Mar - 8 Mar
Tomorrow
8 Mar - 9 Mar
Next weekend
13 Mar - 15 Mar
In two weeks
20 Mar - 22 Mar

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Florence hotels

Lobby

Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
2.5 star property
Florence
9.0 out of 10, Wonderful, (2,252 reviews)
"Room was clean, staff friendly, and the includes breakfast was great "
United States
Samantha
The price is NZ$162
includes taxes & fees
15 Mar - 16 Mar
Park Inn by Radisson Florence, SC
Lobby

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
2.5 star property
Florence
9.2 out of 10, Wonderful, (1,239 reviews)
"Great location, friendly staff. "
United States
Defelicio
The price is NZ$187
includes taxes & fees
8 Mar - 9 Mar
Comfort Inn & Suites Florence Center Area
Terrace/patio

Hyatt Place Florence Downtown

Hyatt Place Florence Downtown
3.0 star property
Florence
9.0 out of 10, Wonderful, (1,005 reviews)
"Great location and well maintained property. "
United States
Karen
The price is NZ$222
includes taxes & fees
15 Mar - 16 Mar
Hyatt Place Florence Downtown
Lobby

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
2.0 star property
Florence
8.6 out of 10, Excellent, (2,584 reviews)
"I nice place to stay, very quiet, good breakfast, nice staff, spotless room. "
United States
Timothy
The price is NZ$133
includes taxes & fees
11 Mar - 12 Mar
Howard Johnson by Wyndham Florence
Exterior

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
2.5 star property
Florence
9.2 out of 10, Wonderful, (1,008 reviews)
"Clean rooms and nice breakfast. "
United States
Adam
The price is NZ$232
includes taxes & fees
15 Mar - 16 Mar
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
Terrace/patio

Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
2.5 star property
Florence
8.4 out of 10, Very good, (1,004 reviews)
"We enjoyed our stay. Everything stood out Staff, Clean room and Amenities. "
United States
Marita
The price is NZ$191
includes taxes & fees
29 Mar - 30 Mar
Tru by Hilton Florence I-95
Lobby

La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence
3.0 star property
Florence
7.8 out of 10, Good, (1,674 reviews)
"Clean rooms, friendly staff, great breakfast "
United States
Donna
The price is NZ$198
includes taxes & fees
15 Mar - 16 Mar
La Quinta Inn & Suites by Wyndham Florence
Restaurant

Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
2.5 star property
Florence
9.0 out of 10, Wonderful, (857 reviews)
"Staff was very kind and conscious of our needs"
United States
Robert
The price is NZ$210
includes taxes & fees
15 Mar - 16 Mar
Hampton Inn & Suites Florence Center
Lobby

Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
2.5 star property
Florence
7.8 out of 10, Good, (1,276 reviews)
"Quiet clean and many options local for food etc Good for a night or two stay Bed was comfortable "
United States
Louis
The price is NZ$178
includes taxes & fees
9 Mar - 10 Mar
Quality Inn & Suites Florence Civic Center
Desk, iron/ironing board, free WiFi, bed sheets

Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center
2.5 star property
Florence
7.0 out of 10, Good, (1,007 reviews)
"Love this room dearly"
United States
Andre
The price is NZ$126
includes taxes & fees
16 Mar - 17 Mar
Days Inn by Wyndham Florence Near Civic Center
Studio, Multiple Beds

TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
3.0 star property
Florence
9.0 out of 10, Wonderful, (769 reviews)
"Checking in was a breeze and the staff was excellent. "
United States
Tiffany
The price is NZ$200
includes taxes & fees
15 Mar - 16 Mar
TownePlace Suites by Marriott Florence
Reception

Hilton Garden Inn Florence

Hilton Garden Inn Florence
2.5 star property
Florence
8.6 out of 10, Excellent, (285 reviews)
"The hotel is very pet friendly. Close to stores and restaurants. Clean, friendly, for is great in the restaurant in the hotel as well. "
United States
Michelle
The price is NZ$216
includes taxes & fees
29 Mar - 30 Mar
Hilton Garden Inn Florence
View from property

Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
3.0 star property
Florence
9.2 out of 10, Wonderful, (592 reviews)
"Friendly staff, clean and comfortable room "
United States
craig
The price is NZ$216
includes taxes & fees
29 Mar - 30 Mar
Fairfield Inn & Suites by Marriott Florence I-20
Room, 1 Queen Bed, Accessible, Non Smoking

Microtel Inn & Suites by Wyndham Florence

Microtel Inn & Suites by Wyndham Florence
2.0 star property
Florence
6.8 out of 10, (1,005 reviews)
"Friendly staff, clean room, very comfortable bed "
United States
Willie
The price is NZ$118
includes taxes & fees
6 Apr - 7 Apr
Microtel Inn & Suites by Wyndham Florence
Exterior

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
2.5 star property
Florence
8.4 out of 10, Very good, (1,006 reviews)
"Friendly staff, quick check in, nice lobby"
United States
Jennifer
The price is NZ$249
includes taxes & fees
29 Mar - 30 Mar
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
Exterior

Rodeway Inn Florence Downtown

Rodeway Inn Florence Downtown
2.0 star property
Florence
6.0 out of 10, (2 reviews)
"Good"
United States
Joshua
The price is NZ$95
includes taxes & fees
6 Apr - 7 Apr
Rodeway Inn Florence Downtown
Exterior

Affordable Suites Florence

Affordable Suites Florence
2.5 star property
Florence
9.2 out of 10, Wonderful, (141 reviews)
"Nice clean room; friendly staff"
United States
Angelo
Affordable Suites Florence
Restaurant

Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
2.5 star property
Florence
9.0 out of 10, Wonderful, (873 reviews)
"The employees were so nice!"
United States
ron
The price is NZ$224
includes taxes & fees
6 Apr - 7 Apr
Hampton Inn & Suites Florence-North-I-95
Exterior

Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
3.0 star property
Florence
9.4 out of 10, Exceptional, (963 reviews)
"Room clean, bed good, breakfast good choices, front desk excellent"
United States
mona
The price is NZ$256
includes taxes & fees
29 Mar - 30 Mar
Staybridge Suites Florence - Civic Center by IHG
Lobby

Residence Inn Marriott Florence

Residence Inn Marriott Florence
3.0 star property
Florence
8.8 out of 10, Excellent, (521 reviews)
"Clean room, great location, easy check-in & check-out, friendly service"
United States
Shaun
The price is NZ$204
includes taxes & fees
23 Mar - 24 Mar
Residence Inn Marriott Florence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

The Annual Holiday Sale

Members save up to 40% on hotels and homes. Plan this year’s big trip and save.
Book now
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Stay near popular Florence attractions

Florence_FlorenceCivicCenter_6165605_0005

Florence Civic Center

4.0/5 (308 reviews)
The Florence Centre hosts everything from electrifying concerts to expansive trade shows in its modern South Carolina venue. Arrive early to navigate security and enjoy the state-of-the-art facilities.
See properties
Florence_MagnoliaMall_6165602_0005

Magnolia Mall

4.0/5 (410 reviews)
This spacious retail hub at the crossroads of two major interstates is Florence's premier shopping destination. Browse national retailers, enjoy diverse dining, or entertain the family at Tilt Studio.
See properties

Florence and related destinations

Stroll through the West Broad Street Historic District to soak up local history before exploring the Florence Museum's diverse exhibits. Catch a show at the Florence Civic Centre or hunt for bargains at Magnolia Mall for a taste of modern entertainment.

See all hotels in Florence
Wyche Pavilion Greenville South Carolina

Top Florence Hotel Reviews

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

10/10 Excellent
"Great stay!! I highly recommend!! Very clean and friendly staff!!"
Chad 1-night trip
Posted 1 hour ago
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

More cheap accommodation in Florence

Microtel Inn & Suites by Wyndham Florence

Microtel Inn & Suites by Wyndham Florence

1912 Enterprise Dr Florence SC
The price is NZ$118 per night from 6 Apr to 7 Apr
NZ$118
6 Apr - 7 Apr
includes taxes & fees
6.8/10 (1,005 reviews)

Frequently asked questions

What's the best place to stay in Florence?
Staybridge Suites Florence - Civic Center by IHG is ranked highly by Expedia customers. This hotel offers free breakfast and a restaurant. Reviews from our site also recommend Fairfield Inn & Suites by Marriott Florence I-20 and Hampton Inn & Suites Florence Center as top options for your stay. See all available top hotels, or vacation rentals in Florence.
What are some of the best holiday rentals that Florence has to offer?
Walking distance from one of South Carolina's top Medical centers.: This highly rated holiday home rental in Florence offers a garden, a selection of games and a BBQ to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. Some other top choices in Florence are Take a rest in Florence .Ideal for i95 traveler and Florence Center and Buc-ee's and Wonderful 2-bedroom house charming ranch style home. See all vacation rentals in Florence.
If I need to cancel my hotel reservation in Florence, will I receive a refund?
Yes, the majority of room reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Florence.
What's the best accommodation for a budget-friendly stay in Florence?
Based on reviews, Park Inn by Radisson Florence, SC is a popular hotel for our travellers who want a more economical choice, and features free buffet breakfast and free Wi-Fi. Other good choices to stay on the cheap include Howard Johnson by Wyndham Florence and La Quinta Inn & Suites by Wyndham Florence. View all budget hotels in Florence.
What's the best family accommodation in Florence?
La Quinta Inn & Suites by Wyndham Florence is a hotel with free parking and free breakfast, and it's a top choice on Expedia for families. Other choices to stay with the children include Howard Johnson by Wyndham Florence and Quality Inn & Suites Florence Civic Center. Find more child-friendly accommodations in Florence.
What is the top LGBTQ-friendly place to stay in Florence?
TownePlace Suites by Marriott Florence is a top LGBTQ-friendly hotel that features free breakfast and free parking. Tru by Hilton Florence I-95 and Courtyard by Marriott Florence are two other good options for your stay. See all available hotels listed as LGBTQ-friendly in Florence.
What's the best dog-friendly place to stay in Florence?
Park Inn by Radisson Florence, SC is a top hotel for people travelling with their pets, and offers a 24-hour fitness centre and free WiFi for its human guests. Other good options for you and your pet's trip include Comfort Inn & Suites Florence Center Area and Residence Inn Marriott Florence. See more pet-friendly hotel accommodations in Florence.
What are some accommodation options with pools in Florence?
Hyatt Place Florence Downtown is a top hotel with an outdoor pool, free breakfast and free WiFi. A couple of other options that feature an on-site pool include Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG and Homewood Suites by Hilton Florence. View all hotels with pools in Florence.
What is the best spa hotel in Florence?
Hotel Florence, Tapestry Collection by Hilton is a top spa hotel featuring a 24-hour fitness centre, a bar and a restaurant. Enjoy a facial, detox wrap or Swedish massage at the on-site spa. See all spa hotels in Florence.
What is staying in Florence like?
Families will find child-friendly activities in Florence, and visitors give high marks for the top-notch restaurants and shopping. This welcoming city also attracts tourists with its entertainment. In Florence, there are 112 hotels and other accommodation options to choose from. Find out more about Florence.
What are the top places to visit in Florence?
Landmarks like Mcleod Regional Medical Center, Florence National Cemetery and Drs Bruce and Lee Foundation Library might be worth a visit. A couple of additional sights to add to your itinerary are Florence Museum and Dr. Eddie Floyd Tennis Center. Take a look at what more there is to see and do in Expedia's Florence guide.
How can I get around Florence?
If you want to explore the larger area, take a train from Florence Station. If you want to venture out around the area, you may want a rental car in Florence for your journey.
What's the weather like in Florence?
The hottest months are usually July and August, with an average temperature of 26°C, while the coldest months are January and February, with an average of 10°C. Average annual precipitation for Florence is 1366 mm.

Explore a world of travel with Expedia