A visit to the destination enshrined as Natural and Cultural Heritage of Humanity (UNESCO) crossing the homonymous ravine, discovering exceptional landscapes, towns and cultures. Unique towns are shown, such as Purmamarca, famous for the setting of the Cerro de los Siete Colores, Maimará, with colourful slopes called Paleta del Pintor. Tilcara stands out for its Pucará (high fortress) whose ruins have been partially destroyed.

Uquía shows its chapel, built in the 17th century, worked in laminated gold, Humahuaca gives its name to the Quebrada and is its largest population, with cobbled streets and iron lampposts on the corners, it is also the highest point of the route, 2,940 metres above sea level. Main attractions: The Independence Monument, Cathedral Church and Municipal Building.