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Top Romantic Southeast Minnesota Hotels

Alexander Mansion Bed and Breakfast

274 East Broadway Winona MN

2 hours drive from Mayo Clinic

Stay at this B&B in Winona. Enjoy free parking, a business centre and daily housekeeping. Popular attractions Winona Arts Center and Watkins Heritage Museum ...

9.8/10 Exceptional! (520 reviews)

"Richard was fantastic"

Reviewed on 2 July 2026

St James Hotel, a Historic Hotel of America

406 Main St. Red Wing MN

2 hours drive from Mayo Clinic

Stay at this spa hotel in Red Wing. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff and the comfy rooms in their reviews. ...

9.2/10 Wonderful! (1,000 reviews)

"The best place to stay by far in Red Wing. Centrally located in downtown including adjacent to the Amtrak station which is how we arrived. They also have good bikes for rent - perfect as we didn’t have a car. Well maintained historic facility with interesting old photos, plaques, and artifacts everywhere ..."

Reviewed on 3 July 2026

AmericInn by Wyndham Austin

1700 8th St NW Austin MN

2 hours drive from Mayo Clinic

Stay at this business-friendly hotel in Austin. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms in ...

8.8/10 Excellent! (762 reviews)

"We had a very nice stay with our grand daughter. Walking distance to Perkins restaurant for supper and a nice hot continental breakfast in the morning before hitting the road."

Reviewed on 1 July 2026

See all 921 properties in Southeast Minnesota

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.