Plan, book, travel with confidence
Better together
Save up to NZ$2,400 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place

Top Romantic Mesopotamia Hotels

Hotel das Cataratas, A Belmond Hotel, Iguassu Falls

Rodovia Br 469 Km 32 Foz do Iguaçu PR

17 hours drive from Termas de Federacion

Stay at this luxury hotel in Foz do Iguaçu. Enjoy free breakfast, free Wi-Fi and a full-service spa. Our guests praise the helpful staff and the property condition ...

10/10 Exceptional! (1,001 reviews)

"The organisation and attentiveness of the staff was absolutely top rated. Even if they got something wrong they came over and apologised and made it clear they would try harder. I have never seen such a positive and open way to continually improve things. Room servicing was attentive and discrete. ..."

Reviewed on 13 June 2026

La Aldea de la Selva Lodge

Selva Iriapú S / N Puerto Iguazú Misiones

17 hours drive from Termas de Federacion

Stay at this business-friendly lodge in Puerto Iguazú. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. ...

8.8/10 Excellent! (571 reviews)

"Our stay was perfect. The staff were very friendly and kind. The cabin I was in was beautiful and private."

Reviewed on 26 June 2026

IGUAZU JUNGLE HOTEL

Avenida Hipolito Irigoyen s/n Puerto Iguazú Misiones

17 hours drive from Termas de Federacion

Stay at this family-friendly hotel in Puerto Iguazú. Enjoy free breakfast, free Wi-Fi and room service. Our guests praise the restaurant and the helpful staff ...

9.4/10 Exceptional! (856 reviews)

"Excellent place for your vacation"

Reviewed on 26 June 2026

See all 526 properties in Mesopotamia

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.