Top Pet-friendly Southern Minnesota Hotels

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

4353 Canal Pl SE, Rochester, MN

11 min drive from Mayo Clinic

Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...

7.2/10 Good! (1,008 reviews)

"Everything was just okay"

Reviewed on 11 Oct 2025

Med City Inn & Suites - Mayo Clinic Area

435 16th Ave Nw, Rochester, MN

26 min walk from Mayo Clinic

Book a stay at this family-friendly motel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

7.8/10 Good! (1,006 reviews)

"The place was well kept and clean even with the old carpet in our room. Beds were comfortable and loved accommodation for my disability. The location was close to Mayo wich made it easier for traveling. Loved the cosey family feeling and breakfast was a good bonus. Staff were patientv& friendly Room ..."

Reviewed on 12 Oct 2025

Spark by Hilton Rochester South

4165 Maine Ave SE, Rochester, MN

10 min drive from Mayo Clinic

Stay at this 3-star business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...

9.2/10 Wonderful! (209 reviews)

"This is a perfectly fine short-term hotel, I'm just perplexed by the 9.4 traveler rating which is what led me to select it. Highlights: it was clean and smelled remodeled. Otherwise: tiny lobby, sad little breakfast, small bath, backlot location, tiny exercise room (three walking machines plus barbells) ..."

Reviewed on 13 Oct 2025

See all 1,184 properties in Southern Minnesota

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.