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Top Mountain Upstate South Carolina Hotels

Drury Inn & Suites Greenville

10 Carolina Point Pkwy Greenville SC

2 hours drive from Clemson University

Stay at this business-friendly hotel in Greenville. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...

9.6/10 Exceptional! (1,022 reviews)

"Drury does a great job w/ amenities, staff and cleaning. Only minor issues nothing to report."

Reviewed on 26 June 2026

The Westin Poinsett Greenville

120 South Main St Greenville SC

1 hour drive from Clemson University

Stay at this business-friendly hotel in Greenville. Enjoy breakfast (surcharge), a free airport shuttle and 24-hour room service. Our guests praise the helpful ...

9.4/10 Exceptional! (1,000 reviews)

"Always our go to place to stay in Greenville,SC. Never disappointed"

Reviewed on 14 June 2026

Hampton Inn Gaffney

115 Nancy Creek Rd Gaffney SC

3 hours drive from Clemson University

Stay at this hotel in Gaffney. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular attractions Gaffney ...

8.8/10 Excellent! (734 reviews)

"Stayed in room 427 for only one night. The only reason I didn’t give a lower rating was due to the night clerk who was very nice although she seemed like she had a pressing issue that needed to be addressed. The hallway carpet is absolutely disgusting with various stains. Our sink drained so slowly ..."

Reviewed on 22 June 2026

See all 3,017 properties in Upstate South Carolina

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.