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Top Luxury Central Iowa Hotels

Des Lux Hotel

800 Locust St Des Moines IA

1 hour drive from Iowa State University

Stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free Wi-Fi and a free airport shuttle. Our guests praise the breakfast and the bar ...

9.6/10 Exceptional! (1,119 reviews)

"Nice!"

Reviewed on 8 Nov 2026

Sonesta Essential Des Moines

4755 Merle Hay Road Des Moines IA

1 hour drive from Iowa State University

Stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the clean rooms in their reviews. Popular ...

La Quinta Inn & Suites by Wyndham Des Moines West Clive

1390 Nw 118th St Clive IA

1 hour drive from Iowa State University

Stay at this family-friendly hotel in Clive. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in their ...

8.6/10 Excellent! (1,004 reviews)

"Air did not work the best in the room and our key to get in our room did not work for the pool. But staff was Amazing!!!"

Reviewed on 9 Nov 2026

See all 1,581 properties in Central Iowa

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.