Top Luxury Central Iowa Hotels

Des Lux Hotel

800 Locust St, Des Moines, IA

1 hour drive from Iowa State University

Stay at this 3.5-star business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and ...

9.6/10 Exceptional! (1,008 reviews)

"We enjoyed our stay at Des Lux and will definitely be back next time we come through Des Moines. After completing RAGBRAI again we decided to treat ourselves and relax a bit before heading home. The whirlpool was amazing! Spacious and just the right temp. Lots of options for dining nearby. Be sure ..."

Reviewed on 3 Aug. 2025

Sonesta Essential Des Moines

4755 Merle Hay Road, Des Moines, IA

1 hour drive from Iowa State University

Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...

7.2/10 Good! (1,011 reviews)

"ok"

Reviewed on 5 Aug. 2025

La Quinta Inn & Suites by Wyndham Des Moines West Clive

1390 Nw 118th St, Clive, IA

1 hour drive from Iowa State University

Stay at this 3-star family-friendly hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

8.6/10 Excellent! (1,000 reviews)

In Des Moines for Senior Olympics

"Breakfast was good. Room was fine, had microwave, small fridge and microwave. Front desk was helpful. Location good, could walk to Mexican Restaurant and Crack O Barrel."

Reviewed on 30 Jul. 2025

See all 1,494 properties in Central Iowa

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.