Southern Indiana Luxury Holidays 2026

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Top Luxury Southern Indiana Hotels

21c Museum Hotel Louisville

700 W Main Street Louisville KY

3 hours drive from Holiday World and Splashin' Safari

Stay at this luxury hotel in Louisville. Enjoy free Wi-Fi, a full-service spa and breakfast (surcharge). Our guests praise the restaurant and the helpful staff ...

9.4/10 Exceptional! (1,014 reviews)

"I loved how eclectic this hotel was. The museums and all of the artwork were amazing. The moving penguins kept us laughing. We had an issue with our truck and the Valet was so helpful. We loved our nightly nightcap. We will definitely stay here again, and recommend it to others."

Reviewed on 8 Aug 2026

West Baden Springs Hotel

8538 W Baden Ave West Baden Springs IN

1 hour drive from Holiday World and Splashin' Safari

Stay at this luxury resort in West Baden Springs. Enjoy free Wi-Fi, a full-service spa and 15 restaurants. Popular attractions French Lick Winery and FLWB Indoor ...

The Brown Hotel

335 W Broadway Louisville KY

3 hours drive from Holiday World and Splashin' Safari

Stay at this luxury hotel in Louisville. Enjoy free Wi-Fi, breakfast (surcharge) and a free airport shuttle. Our guests praise the helpful staff and the clean ...

9.4/10 Exceptional! (1,286 reviews)

"The restaurants and bar had outstanding service and delicious food. All hotel staff we encountered were friendly and helpful. The beautiful historic lobby is so nice to enjoy. The location is very convenient for The Palace."

Reviewed on 7 Aug 2026

See all 1,617 properties in Southern Indiana

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.