Top Luxury Eastern South Dakota Hotels

Baymont by Wyndham Sioux Falls West (67058) Sioux/ Near Airport

3101 W Russell St, Sioux Falls, SD

25 min walk from Denny Sanford Premier Center

Book a stay at this business-friendly hotel in Sioux Falls. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

6.6/10 (1,008 reviews)

"An easy, off the interstate hotel, great for stopping to get a few hours sleep while traveling. Has lots of dated and broken odds and ends. But the staff (both the night and early morning) are friendly and helpful and professional."

Reviewed on 19 Sept 2025

Econo Lodge Sioux Falls Empire Mall

3500 Gateway Boulevard, Sioux Falls, SD

9 min drive from Denny Sanford Premier Center

Book a stay at this business-friendly hotel in Sioux Falls. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Denny Sanford Premier Center ...

Economy hotel, no thrills, but it's nice

"Staff was really nice. Rooms are spacious. Good value and convenient to many stores/restaurants, etc. Rooms for clean."

Reviewed on 18 Oct 2022

My Place Hotel - Sioux Falls, SD

3005 S. Carolyn Ave, Sioux Falls, SD

8 min drive from Denny Sanford Premier Center

Book a stay at this business-friendly hotel in Sioux Falls. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and ...

8.4/10 Very Good! (1,008 reviews)

"Great place for an overnight stay. Clean, comfortable, convenient. Good value."

Reviewed on 17 Sept 2025

See all 836 properties in Eastern South Dakota

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.