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Top Luxury Central Mississippi Hotels

Microtel Inn & Suites by Wyndham Meridian

518 Bonita Lakes Dr, Meridian, MS

3 hours drive from Mississippi State University

Book a stay at this business-friendly hotel in Meridian. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...

6.2/10 (1,014 reviews)

Cockroaches and dead bugs all over my room. I need something to fix this. How am I to know if they have already laid eggs on my clothes or in my belongings. Now I’m going to have to fly back home and c throw away everything

Reviewed on 28 Oct 2025

Red Roof Inn Meridian

2219 S Frontage Rd, Meridian, MS

3 hours drive from Mississippi State University

Book a stay at this business-friendly hotel in Meridian. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our ...

6.4/10 (925 reviews)

Very polite staff members.

Reviewed on 20 Aug 2025

Comfort Inn & Suites Columbus North

129 Brickerton St, Columbus, MS

32 min drive from Mississippi State University

Book a stay at this business-friendly hotel in Columbus. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...

7.2/10 Good! (797 reviews)

I loved my stay

Reviewed on 15 Oct 2025

See all 432 properties in Central Mississippi

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.