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Top Luxury Central Mississippi Hotels

Microtel Inn & Suites by Wyndham Meridian

518 Bonita Lakes Dr Meridian MS

3 hours drive from Mississippi State University

Stay at this business-friendly hotel in Meridian. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular ...

6.2/10 (999 reviews)

Coffee was decent. Staff was great. Its a tired hotel that needs updating. Price was hood.

Reviewed on 19 Apr 2026

Red Roof Inn Meridian

2219 S Frontage Rd Meridian MS

3 hours drive from Mississippi State University

Stay at this business-friendly hotel in Meridian. Enjoy free Wi-Fi, free parking and a 24-hour front desk. Our guests praise the helpful staff in their reviews. ...

Comfort Inn & Suites Columbus North

129 Brickerton St Columbus MS

32 min drive from Mississippi State University

Stay at this business-friendly hotel in Columbus. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular ...

7.4/10 Good! (839 reviews)

Comfortable and very friendly staff

Reviewed on 28 Apr 2026

See all 476 properties in Central Mississippi

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.