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Top Luxury Central Mississippi Hotels

Microtel Inn & Suites by Wyndham Meridian

518 Bonita Lakes Dr Meridian MS

3 hours drive from Mississippi State University

Stay at this business-friendly hotel in Meridian. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular ...

6.2/10 (1,002 reviews)

"It's quite cheap"

Reviewed on 23 June 2026

Red Roof Inn Meridian

2219 S Frontage Rd Meridian MS

3 hours drive from Mississippi State University

Stay at this business-friendly hotel in Meridian. Enjoy free Wi-Fi, free parking and a 24-hour front desk. Our guests praise the helpful staff in their reviews. ...

6.6/10 (961 reviews)

"Its a clean hotel."

Reviewed on 15 June 2026

Comfort Inn & Suites Columbus North

129 Brickerton St Columbus MS

32 min drive from Mississippi State University

Stay at this business-friendly hotel in Columbus. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular ...

7.4/10 Good! (861 reviews)

"The rooms are clean and the breakfast bar has been good. I have stayed here about four times over the past two years and the breakfast buffet is always good."

Reviewed on 23 June 2026

See all 478 properties in Central Mississippi

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.