South America Luxury Holidays
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Top flight + Luxury hotel deals in South America
Price found within the past 48 hours. Click for updated prices.
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See all available trips from Columbus to South America
View all trips5* Luxury holidays in South America
Price found within the past 48 hours. Click for updated prices.
Don't see what you're looking for?
See all available trips from Columbus to South America
View all tripsTop Luxury South America Hotels
Hotel das Cataratas, A Belmond Hotel, Iguassu Falls
Rodovia Br 469 Km 32, Iguassu National Park, Foz do Iguaçu, PR
The price is NZ$1,282 per night from 1 Aug to 2 Aug
NZ$1,282
1 Aug - 2 Aug
includes taxes & fees
Stay at this 5-star luxury hotel in Foz do Iguaçu. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff and the property ...
9.8/10 Exceptional! (1,007 reviews)
"Fantastic location."
Reviewed on 20 Jul. 2025
Hotel Club Frances
Rodríguez Peña 1832, Buenos Aires, Capital Federal
The price is NZ$309 per night from 27 July to 28 July
NZ$309
27 July - 28 July
Stay at this 4.5-star luxury hotel in Buenos Aires. Enjoy free breakfast, free WiFi, and a full-service spa. Our guests praise the helpful staff in our reviews. ...
9.4/10 Exceptional! (625 reviews)
"Great hotel. Super location. Very friendly and accommodating staff. Went out of their way to serve us. Tremendous value and walking distance to so much. Would stay again."
Reviewed on 24 Mar. 2025
Palacio del Inka, A Luxury Collection Hotel by Marriott
Plazoleta Santo Domingo No 259, Cusco, Cusco
The price is NZ$716 per night from 1 Aug to 2 Aug
NZ$716
1 Aug - 2 Aug
Stay at this 5-star luxury hotel in Cusco. Enjoy a full-service spa, room service, and a fitness center. Our guests praise the helpful staff in our reviews. ...
9.4/10 Exceptional! (912 reviews)
"The hotel staff were friendly and helpful. The rooms and bathrooms are spacious and clean. The hotel is conveniently located. I would recommend staying here."
Reviewed on 16 Jul. 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.