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Top Luxury San Luis Obispo Wine Country Hotels

Madonna Inn

100 Madonna Road San Luis Obispo CA

6 min drive from California Polytechnic State University

Stay at this spa hotel in San Luis Obispo. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the pool and the helpful staff in their reviews. ...

9.2/10 Wonderful! (1,356 reviews)

This is such a unique place to stay, each room is decorated in its own theme, including rock walls and waterfalls in some of the bathrooms. It's quiet, despite being just off the freeway, except for a chorus of frogs to sing you to sleep. Staff is wonderful and helpful, and the food is great! A nice, ...

Reviewed on 17 Jan 2026

Avenue Inn Downtown San Luis Obispo

345 Marsh St San Luis Obispo CA

4 min drive from California Polytechnic State University

Stay at this motel in San Luis Obispo. Enjoy free Wi-Fi, free parking and premium TV channels. Our guests praise the helpful staff and the clean rooms in their ...

9/10 Wonderful! (1,156 reviews)

Haha, continental breakfast was coffee and a granola bar. But, you don't book a hotel for the breakfast. We usually stay elsewhere when visiting Cal Poly. The price was about half of where we typically stay so tried out. Not exactly modern, but very clean. Staff was super pleasant, asked for upstairs ...

Reviewed on 20 Jan 2026

Avila La Fonda Hotel

101 San Miguel St Avila Beach CA

22 min drive from California Polytechnic State University

Stay at this golf hotel in Avila Beach. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular attractions ...

9.4/10 Exceptional! (1,000 reviews)

A great place to stay for adults! Our room was clean and snacks are provided for free. There was a room to either exchange the snacks for different ones or buy extra snacks. That same room also provides movies to borrow and chairs to take to the beach. There are several times to get food for free. ...

Reviewed on 19 Jan 2026

See all 1,860 properties in San Luis Obispo Wine Country

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.