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Top Cheap Panhandle Plains Hotels

Studio 6 Amarillo, TX – West Medical Center

6801 W Interstate 40, Amarillo, TX

4 hours drive from Texas Tech University

Book a stay at this business-friendly hotel in Amarillo. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the breakfast and the pool ...

7.4/10 Good! (1,001 reviews)

"It was right off the interstate highway"

Reviewed on 21 Jul. 2025

Days Inn by Wyndham Amarillo East

1701 I-40E, I-40 Exit 71 Ross-Osage, Amarillo, TX

4 hours drive from Texas Tech University

Book a stay at this business-friendly hotel in Amarillo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

6.6/10 (1,008 reviews)

Bathroom vanity needs help

"Bathroom sink and vanity area could use a little freshening up. I couldn't turn off the TV without unplugging it which might explain why it was on when I entered the room."

Reviewed on 5 Aug. 2025

Extend-a-Suites - Extended Stay, I-40 Amarillo West

3411 I-40 W, Amarillo, TX

4 hours drive from Texas Tech University

Stay at this hotel in Amarillo. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions The Galleries at Sunset Center and Amarillo Little ...

4.8/10 (1,001 reviews)

"Curtains are full of holes"

Reviewed on 20 Jul. 2025

See all 2,039 properties in Panhandle Plains

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.