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Top Cheap Panhandle Plains Hotels

Studio 6 Amarillo, TX – West Medical Center

6801 W Interstate 40 Amarillo TX

4 hours drive from Texas Tech University

Stay at this business-friendly hotel in Amarillo. Enjoy free Wi-Fi, free parking and a 24-hour front desk. Our guests praise the breakfast and the pool in their ...

7.4/10 Good! (1,014 reviews)

Room clean enough. Breakfast was supposed to be serverd till 9:30. Went down at 9 & it was already closed up.

Reviewed on 23 Nov 2025

Days Inn by Wyndham Amarillo East

1701 I-40E Amarillo TX

4 hours drive from Texas Tech University

Stay at this business-friendly hotel in Amarillo. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms ...

6.8/10 (1,006 reviews)

Peaceful and quiet

Reviewed on 28 Nov 2025

Extend-a-Suites - Extended Stay, I-40 Amarillo West

3411 I-40 W Amarillo TX

4 hours drive from Texas Tech University

Stay at this hotel in Amarillo. Enjoy free Wi-Fi, free parking and a 24-hour front desk. Popular attractions The Galleries at Sunset Center and Amarillo Little ...

4.8/10 (1,000 reviews)

Two thumbs up

Great staff and clean rooms.

Reviewed on 22 Aug 2025

See all 2,175 properties in Panhandle Plains

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.