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Top Cheap Panhandle Plains Hotels

Studio 6 Amarillo, TX – West Medical Center

6801 W Interstate 40, Amarillo, TX

4 hours drive from Texas Tech University

Book a stay at this business-friendly hotel in Amarillo. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the breakfast and the pool ...

7.4/10 Good! (1,007 reviews)

"Price gauging because of the construction going on. RENT kept increasing every week. 303.00 to 367.00 To 414.00 a week. Other than that very quiet place and rooms are very clean."

Reviewed on 14 Sept 2025

Days Inn by Wyndham Amarillo East

1701 I-40E, I-40 Exit 71 Ross-Osage, Amarillo, TX

4 hours drive from Texas Tech University

Book a stay at this business-friendly hotel in Amarillo. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

6.6/10 (1,006 reviews)

"Pricing excellent and conditions appropriate for our one night stay."

Reviewed on 16 Sept 2025

Extend-a-Suites - Extended Stay, I-40 Amarillo West

3411 I-40 W, Amarillo, TX

4 hours drive from Texas Tech University

Stay at this hotel in Amarillo. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions The Galleries at Sunset Center and Amarillo Little ...

4.8/10 (1,001 reviews)

Two thumbs up

"Great staff and clean rooms."

Reviewed on 22 Aug 2025

See all 2,131 properties in Panhandle Plains

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.