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Top Beach Upstate South Carolina Hotels

😎Anchors Down Lakeside Retreat 15 min to Clemson🏈 Dock, Padle boat, Kayaks

Seneca SC

21 min drive from Clemson University

Stay at this beach holiday home in Seneca. Enjoy free Wi-Fi, a beach locale and a garden. Popular attractions Friendship Recreaction Area and Cross Creek Plantation ...

Quality Inn Clinton - Laurens I-26

105 Trade St Clinton SC

3 hours drive from Clemson University

Stay at this business-friendly hotel in Clinton. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular ...

7.4/10 Good! (558 reviews)

"The room was okay. The pillow cases were a little dingy and room missing hairdryer"

Reviewed on 18 July 2026

Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

801 Spartan Blvd Spartanburg SC

2 hours drive from Clemson University

Stay at this hotel in Spartanburg. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular attractions ...

See all 3,049 properties in Upstate South Carolina

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.