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Top Adventure Mesopotamia Hotels

Iguazú Grand Hotel

Route 12 Km 1640 Puerto Iguazú Misiones

17 hours drive from Termas de Federacion

Stay at this luxury hotel in Puerto Iguazú. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular ...

9.2/10 Wonderful! (700 reviews)

"The property was good and most folks were welcoming and helpful the WiFi was strange and one of my laptop couldn’t linkup and one of the staff refused to make us an extra key"

Reviewed on 26 Oct 2026

Hotel das Cataratas, A Belmond Hotel, Iguassu Falls

Rodovia Br 469 Km 32 Foz do Iguaçu PR

17 hours drive from Termas de Federacion

Stay at this luxury hotel in Foz do Iguaçu. Enjoy free breakfast, free Wi-Fi and a full-service spa. Our guests praise the helpful staff and the property condition ...

Gran Melia Iguazú

Parque Nacional Iguazu Puerto Iguazú Misiones

17 hours drive from Termas de Federacion

Stay at this luxury hotel in Puerto Iguazú. Enjoy free breakfast, free Wi-Fi and 2 outdoor pools. Our guests praise the helpful staff in their reviews. Popular ...

9.4/10 Exceptional! (1,000 reviews)

"Everything was great"

Reviewed on 28 Oct 2026

See all 532 properties in Mesopotamia

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.