
Popular airlines from Des Moines International Airport (DSM) to Chicago O'Hare International Airport (ORD)
- Delta
Delta
- American Airlines
American Airlines
- United
United
- Southwest Airlines
Southwest Airlines
- Frontier Airlines
Frontier Airlines
- Plan, book, fly with confidence
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Cheap Flights from Des Moines (DSM) to Chicago (ORD)
Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, 13 Sep. - Mon, 15 Sep.
DSM
Des Moines
ORD
Chicago
NZ$299 Return, found 6 days ago
NZ$299
Return
found 6 days ago

Thu, 25 Sep. - Thu, 2 Oct.
DSM
Des Moines
ORD
Chicago
NZ$319 Return, found 1 day ago
NZ$319
Return
found 1 day ago

Mon, 22 Sep. - Mon, 29 Sep.
DSM
Des Moines
ORD
Chicago
NZ$320 Return, found 4 days ago
NZ$320
Return
found 4 days ago

Sat, 13 Sep. - Mon, 15 Sep.
DSM
Des Moines
ORD
Chicago
NZ$321 Return, found 6 days ago
NZ$321
Return
found 6 days ago

Mon, 22 Sep. - Mon, 29 Sep.
DSM
Des Moines
ORD
Chicago
NZ$353 Return, found 4 days ago
NZ$353
Return
found 4 days ago

Thu, 25 Sep. - Thu, 2 Oct.
DSM
Des Moines
ORD
Chicago
NZ$357 Return, found 1 day ago
NZ$357
Return
found 1 day ago

Sat, 13 Sep. - Mon, 15 Sep.
DSM
Des Moines
ORD
Chicago
NZ$378 Return, found 6 days ago
NZ$378
Return
found 6 days ago

Thu, 25 Sep. - Thu, 2 Oct.
DSM
Des Moines
ORD
Chicago
NZ$382 Return, found 1 day ago
NZ$382
Return
found 1 day ago

Thu, 25 Sep. - Thu, 2 Oct.
DSM
Des Moines
ORD
Chicago
NZ$386 Return, found 1 day ago
NZ$386
Return
found 1 day ago

Mon, 22 Sep. - Mon, 29 Sep.
DSM
Des Moines
ORD
Chicago
NZ$387 Return, found 4 days ago
NZ$387
Return
found 4 days ago

Sat, 13 Sep. - Mon, 15 Sep.
DSM
Des Moines
ORD
Chicago
NZ$388 Return, found 6 days ago
NZ$388
Return
found 6 days ago

Mon, 22 Sep. - Mon, 29 Sep.
DSM
Des Moines
ORD
Chicago
NZ$395 Return, found 4 days ago
NZ$395
Return
found 4 days ago

Thu, 25 Sep. - Thu, 2 Oct.
DSM
Des Moines
ORD
Chicago
NZ$451 Return, found 1 day ago
NZ$451
Return
found 1 day ago

Sat, 13 Sep. - Mon, 15 Sep.
DSM
Des Moines
ORD
Chicago
NZ$453 Return, found 6 days ago
NZ$453
Return
found 6 days ago

Sat, 13 Sep. - Mon, 15 Sep.
DSM
Des Moines
ORD
Chicago
NZ$455 Return, found 6 days ago
NZ$455
Return
found 6 days ago
Origin airport | Des Moines Intl. |
Destination airport | O'Hare Intl. |
Airlines serving | American Airlines, Delta |
Return price | NZ$299 |
Distance | 476 km |
Average flight time | 1 hour 31 mins |
Perfect flights from Des Moines to Chicago
Embark on an unforgettable journey without breaking the bank with Expedia's incredible deals on cheap flights from Des Moines to Chicago. Whether you're aching for a romantic escape with your partner, craving an adventurous solo expedition, or yearning to immerse yourself in the local history and culture, we've got you covered.
Picture yourself strolling through the streets of , surrounded by breathtaking architecture and absorbing the vibrant atmosphere of this captivating city. Indulge in the mouth-watering local specialties, from tantalizing street food to exquisite fine dining. With Expedia, you can experience all of this and more, without sacrificing your budget.
Our flexible Des Moines Intl. to O'Hare Intl. ticket options cater to your travel preferences, with incredible one-way fares from NZ$556 and roundtrip prices from NZ$299. Whether you're planning a short city break or a longer adventure, our dynamic pricing ensures that you find the best deals for your journey.
But the magic doesn't stop there. Expedia offers a range of partner services to enhance your trip. Rent a car at O'Hare Intl. and explore and its surrounding areas at your own pace. Discover hidden gems off the beaten path, and create unforgettable memories. We also provide a handpicked selection of accommodations, from charming bed and breakfasts to luxury hotels, ensuring that you have a comfortable and memorable stay.
Planning your next great adventure is a breeze with Expedia. Our user-friendly platform, unbeatable prices, and round-the-clock customer support are designed to make your travel experience seamless and stress-free. So, why wait? Book your to travel arrangements today and embark on the journey of a lifetime in Chicago.
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