
Uptown Greenville Holidays
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Our guide on where to stay in Uptown Greenville
Find the best Uptown Greenville areas and neighborhoods for the activities you enjoy most. Learn more about Uptown Greenville

Medical District
1 out of top 10 points of interest in this area
If you're looking for some top things to see and do in Medical District and surrounding area, you can visit Arlington Crossing and Town Common.
Our pick of the best Uptown Greenville Hotel Deals

Hilton Garden INN Greenville University
423 EVANS ST, Greenville, NC
Fully refundableReserve now, pay when you stay
The price is NZ$262 per night from 2 Nov to 3 Nov
NZ$262
2 Nov - 3 Nov
includes taxes & fees
9.4/10 Exceptional! (69 reviews)
"Beautiful clean and great location"
Reviewed on 14 Sept 2025

Staybridge Suites Greenville Medical Center by IHG
930 Crosswind Street, Greenville, NC
Fully refundable
The price is NZ$204 per night from 2 Nov to 3 Nov
NZ$204
2 Nov - 3 Nov
includes taxes & fees
9.2/10 Wonderful! (138 reviews)
"Bathroom was not cleaned well with water on the floor and there was also hair on the floor."
Reviewed on 1 Oct 2025

Microtel Inn & Suites by Wyndham Greenville/University Medic
450 Moye Blvd, Greenville, NC
Fully refundableReserve now, pay when you stay
The price is NZ$137 per night from 2 Nov to 3 Nov
NZ$137
2 Nov - 3 Nov
includes taxes & fees
7/10 Good! (1,001 reviews)
"Place was well kept! I enjoyed!"
Reviewed on 30 Sept 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.