A modern building with a unique triangular roof and a central spire.

Santa Lucia Hotels, Syracuse

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Our top choices for Santa Lucia hotels

Caportigia Boutique Hotel

Caportigia Boutique Hotel
5.0 star property
Santa Lucia
9.4 out of 10, Exceptional, (287 reviews)
"Beautiful hotel with good amenities"
Canada
Alessia
The price is NZ$393
includes taxes & fees
20 July - 21 July
Caportigia Boutique Hotel

B&B IL MORO

B&B IL MORO
Santa Lucia
The price is NZ$173
includes taxes & fees
30 July - 31 July
B&B IL MORO

Fortaleza Charme House

Fortaleza Charme House
Santa Lucia
10.0 out of 10, Exceptional, (35 reviews)
"Wonderful stay in the center of it all "
United States
lori
The price is NZ$332
includes taxes & fees
18 July - 19 July
Fortaleza Charme House

B&B Nike

B&B Nike
Santa Lucia
9.0 out of 10, Wonderful, (86 reviews)
"Clean, good location. "
United States
Salvatore
The price is NZ$158
includes taxes & fees
23 July - 24 July
B&B Nike

Nostos rooms & Apartments

Nostos rooms & Apartments
3.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (282 reviews)
"Room clean, air-conditioning good, beds good, staff nice. Not really sound proof, but everyone is respectful and quiet during the night. Staff isn't always at the reception, but that didn't bother us. Super central, super safe. There's no lifts though."
United Kingdom
Amanda
The price is NZ$129
includes taxes & fees
17 July - 18 July
Nostos rooms & Apartments

Lakkios

Lakkios
3.0 star property
Santa Lucia
9.2 out of 10, Wonderful, (74 reviews)
"The room appeared to be recently remodeled and was very modern. Of the 4 hotels that we stayed at on this trip, the bed/pillows were the most comfortable. Great view of the marina from our room balcony and public parking (free) was relatively easy. "
United States
Michael
The price is NZ$210
includes taxes & fees
21 July - 22 July
Lakkios

Hotel Palazzo Cavalieri

Hotel Palazzo Cavalieri
4.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (43 reviews)
"Good central location & nice breakfast selection "
Australia
Alan
The price is NZ$281
includes taxes & fees
28 July - 29 July
Hotel Palazzo Cavalieri

Piccolo Hotel Casa Mia

Piccolo Hotel Casa Mia
3.0 star property
Santa Lucia
8.6 out of 10, Excellent, (386 reviews)
"This was my favorite stay in Sicily! I love the elevator and the staff were really nice and accommodating. I also want to point out the excellent AC inside the room. I would only suggest a bottle of water inside the room and a personal tea/ coffee station."
United States
Diane
The price is NZ$164
includes taxes & fees
19 July - 20 July
Piccolo Hotel Casa Mia

Casa Miranda Boutique

Casa Miranda Boutique
Santa Lucia
8.0 out of 10, Very good, (2 reviews)
"Great hotel. Close to everything 15min walk into Ortigia and the excursions dock. The staff are incredibly helpful and thoughtful. Rooms are clean and nice. The balcony had great views of the water and ortigia. Highly recommend to anyone visiting Siracusa! "
United States
Aria
The price is NZ$464
includes taxes & fees
1 Aug - 2 Aug
Casa Miranda Boutique

Re Dionisio Luxury Suites

Re Dionisio Luxury Suites
3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (58 reviews)
"Spacious room, dated but comfortable."
United States
Kenneth
The price is NZ$463
includes taxes & fees
16 July - 17 July
Re Dionisio Luxury Suites

Calafatari B&B

Calafatari B&B
3.0 star property
Santa Lucia
10.0 out of 10, Exceptional, (13 reviews)
"Clean, very convenient for exploring Ortigia. Nice continental breakfast."
United States
Mary
The price is NZ$386
includes taxes & fees
13 Aug - 14 Aug
Calafatari B&B

Regina Margherita

Regina Margherita
Santa Lucia
7.8 out of 10, Good, (17 reviews)
"The area is so close to the Ortigia Island where the beautiful cathedral and Doumo are. Lovely walk around the entire island and areas to go in the water If you like. Many dining options and shopping too. Wonderful area!"
United States
Laura
Regina Margherita

Giuggiulena Villa

Giuggiulena Villa
3.0 star property
Santa Lucia
10.0 out of 10, Exceptional, (129 reviews)
"Amazing stay. Beautiful views and everyone was very friendly. "
United States
Anna
The price is NZ$428
includes taxes & fees
16 July - 17 July
Giuggiulena Villa

Grande Albergo Alfeo

Grande Albergo Alfeo
4.0 star property
Santa Lucia
8.6 out of 10, Excellent, (684 reviews)
"This accommodation was very comfortable and I would highly recommend it."
Australia
Janet
The price is NZ$246
includes taxes & fees
23 July - 24 July
Grande Albergo Alfeo

Melody rooms

Melody rooms
Santa Lucia
The price is NZ$87
includes taxes & fees
24 July - 25 July
Melody rooms

San Nicola Rooms Siracusa

San Nicola Rooms Siracusa
Santa Lucia
9.4 out of 10, Exceptional, (9 reviews)
"The breakfast was great! The hosts were super friendly and helpful!"
United States
Lin
The price is NZ$202
includes taxes & fees
19 July - 20 July
San Nicola Rooms Siracusa

Gymnasium

Gymnasium
3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (42 reviews)
"Nice kitchen area, centrally located."
United States
Richard
The price is NZ$130
includes taxes & fees
19 July - 20 July
Gymnasium

Eos Sea View Apartment

Eos Sea View Apartment
Santa Lucia
10.0 out of 10, Exceptional, (2 reviews)
"Great location and clean apartment."
United States
Siarhei
The price is NZ$297
includes taxes & fees
20 July - 21 July
Eos Sea View Apartment

Hotel Mediterraneo

Hotel Mediterraneo
3.0 star property
Santa Lucia
7.8 out of 10, Good, (124 reviews)
"Very friendly and helpful staff."
United States
David
The price is NZ$179
includes taxes & fees
19 July - 20 July
Hotel Mediterraneo

B&B Siracusa

B&B Siracusa
Santa Lucia
9.0 out of 10, Wonderful, (60 reviews)
"Good location, very modern clean accommodation."
Canada
Malcolm
The price is NZ$142
includes taxes & fees
16 July - 17 July
B&B Siracusa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Santa Lucia

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Breakfast area
Giuggiulena Villa
3.0 star property
10.0
Exceptional
129 reviews
View
Rooftop terrace
Caportigia Boutique Hotel
5.0 star property
9.4
Exceptional
287 reviews
View
Coffee/tea maker, electric kettle
Nostos rooms & Apartments
3.0 star property
9.0
Wonderful
282 reviews
View
Suite, Balcony, Sea View
Lakkios
3.0 star property
9.2
Wonderful
74 reviews
View
Superior Double Room
Fortuna Guest House
1.0 star property
9.2
Wonderful
19 reviews
View

Our guide on where to stay in Santa Lucia

Find the best Santa Lucia areas for the activities you enjoy most.

Ortigia

Ortigia is popular for its seaside views, and if you're looking for more to see and do, you might think about a trip to Cathedral of Syracuse or Piazza del Duomo.

Neapolis

While visiting Neapolis, you might make a stop by sights like Archaeological Park of Neapolis and Greek Theatre of Syracuse.

Grottasanta

Grottasanta is noteworthy for its historical sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

Tiche

Gardens and restaurants are notable features of Tiche. You might consider stopping by Ionian Sea while you're exploring the neighbourhood.

Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

Top Santa Lucia Hotel Reviews

Recent Reviews in Santa Lucia

Frequently asked questions

What is Santa Lucia like?
Santa Lucia is a neighbourhood that people enjoy for its interesting historical sites. Are you looking for Santa Lucia travel tips? Make sure that you visit Porto Piccolo and Ionian Sea while you're in the neighbourhood.
Where is the best hotel for a stay in Santa Lucia?
Based on our traveller data, Grande Albergo Alfeo is one of the top choices for your stay in Santa Lucia. This hotel is a short 9-minute walk from Lungomare di Ortigia, and it offers free breakfast and a restaurant. Other good choices for your stay in the area include Caportigia Boutique Hotel and Fortaleza Charme House.
How many hotels will I find in Santa Lucia?
Expedia has 312 hotels and other accommodation options in Santa Lucia to choose from, making this an ideal home base for exploring the greater Syracuse area.
If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to review the best options available in Santa Lucia.
What are the top things to see and do in Santa Lucia?
Landmarks in Santa Lucia that you won't want to miss include Syracuse Forum Ruins and Santa Lucia Bridge. Porto Piccolo and Ionian Sea are some other stops worth a visit in the neighbourhood. A few places to visit in the area around Santa Lucia include Piazza Santa Lucia, Santa Lucia al Sepolcro Basilica and Madonna delle Lacrime. When you're sightseeing in Syracuse, Papyrus Museum and Museo Archeologico Regionale Paolo Orsi are also worth a stop.

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