Photo by Dean Moore

Top Hotels Near St. Lucie Medical Center in Port Saint Lucie from NZ$143

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
29 Dec - 30 Dec
Tomorrow
30 Dec - 31 Dec
This weekend
2 Jan - 4 Jan
Next weekend
9 Jan - 11 Jan

Filter by

Guest rating
Guest rating
Star rating

Our top choices for St. Lucie Medical Center hotels

Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas, pool loungers
Holiday Inn Port St. Lucie by IHG

Holiday Inn Port St. Lucie by IHG

Holiday Inn Port St. Lucie by IHG
3.0 star property
Sandhill Crossing, 1 km from St. Lucie Medical Center
6.8 out of 10, (1002)
"The room was spot less and the staff was very helpful."
United States
Edward
The price is NZ$211
includes taxes & fees
13 Jan - 14 Jan 2026
Holiday Inn Port St. Lucie by IHG
Outdoor pool, pool loungers
Best Western Port St. Lucie

Best Western Port St. Lucie

Best Western Port St. Lucie
2.5 star property
4.3 km from St. Lucie Medical Center
8.6 out of 10, Excellent, (1005)
"Love this place. Great place with a lot of space."
United States
Bradley
The price is NZ$207
includes taxes & fees
18 Jan - 19 Jan 2026
Best Western Port St. Lucie
Desk, free WiFi, bed sheets
Home2 Suites by Hilton Stuart

Home2 Suites by Hilton Stuart

Home2 Suites by Hilton Stuart
3.0 star property
7.9 km from St. Lucie Medical Center
9.4 out of 10, Exceptional, (608)
"Love staying here. The staff are wonderful, the rooms are clean and the breakfast is decent with lots of options. "
United States
Heather
The price is NZ$249
includes taxes & fees
4 Jan - 5 Jan 2026
Home2 Suites by Hilton Stuart
Exterior
Hampton Inn & Suites Stuart-North

Hampton Inn & Suites Stuart-North

Hampton Inn & Suites Stuart-North
2.5 star property
8.3 km from St. Lucie Medical Center
8.8 out of 10, Excellent, (1006)
"Staff warm and friendly and helpful with local spots to visit! "
United States
CHRISTY
The price is NZ$266
includes taxes & fees
2 Jan - 3 Jan 2026
Hampton Inn & Suites Stuart-North
40-inch TV with cable channels
Old Colorado Inn

Old Colorado Inn

Old Colorado Inn
3.5 star property
10.7 km from St. Lucie Medical Center
9.8 out of 10, Exceptional, (680)
"Perfect location. Quaint place to stay."
United States
Stephen
Old Colorado Inn
Bar (on property)
The Lucie

The Lucie

The Lucie
3.0 star property
9.5 km from St. Lucie Medical Center
9.0 out of 10, Wonderful, (1004)
"The room was great, the view of sunrise was fantastic, and everyone had a smile!"
United States
Jim
The price is NZ$398
includes taxes & fees
1 Jan - 2 Jan 2026
The Lucie
On the beach, sun-loungers, beach umbrellas, beach towels
Hutchinson Shores Resort & Spa

Hutchinson Shores Resort & Spa

Hutchinson Shores Resort & Spa
4.0 star property
10.7 km from St. Lucie Medical Center
9.4 out of 10, Exceptional, (1002)
"I would definitely visit again."
United States
Cassandra
The price is NZ$532
includes taxes & fees
1 Jan - 2 Jan 2026
Hutchinson Shores Resort & Spa
Outdoor pool, pool loungers
Vistana Beach Club

Vistana Beach Club

Vistana Beach Club
3.5 star property
9.2 km from St. Lucie Medical Center
9.2 out of 10, Wonderful, (119)
"VERY NICE"
United States
Rikke
The price is NZ$443
includes taxes & fees
5 Jan - 6 Jan 2026
Vistana Beach Club
BBQ/picnic Area
Residence Inn by Marriott Port St. Lucie

Residence Inn by Marriott Port St. Lucie

Residence Inn by Marriott Port St. Lucie
3.0 star property
11.7 km from St. Lucie Medical Center
9.2 out of 10, Wonderful, (1006)
"Great stay! Very friendly staff "
United States
Giovanni
The price is NZ$244
includes taxes & fees
2 Jan - 3 Jan 2026
Residence Inn by Marriott Port St. Lucie
Exterior
SpringHill Suites Port St. Lucie

SpringHill Suites Port St. Lucie

SpringHill Suites Port St. Lucie
3.0 star property
Saint Lucie West, 11.8 km from St. Lucie Medical Center
8.6 out of 10, Excellent, (1006)
"Great stay"
United States
Craig
The price is NZ$213
includes taxes & fees
3 Jan - 4 Jan 2026
SpringHill Suites Port St. Lucie
Standard Room, 2 Queen Beds, Accessible
Days Inn & Suites by Wyndham Fort Pierce Midtown

Days Inn & Suites by Wyndham Fort Pierce Midtown

Days Inn & Suites by Wyndham Fort Pierce Midtown
2.0 star property
13.6 km from St. Lucie Medical Center
6.8 out of 10, (1002)
"Location was good"
United States
Chokri
The price is NZ$163
includes taxes & fees
31 Dec - 1 Jan 2026
Days Inn & Suites by Wyndham Fort Pierce Midtown
Free daily buffet breakfast
TownePlace Suites by Marriott Port St. Lucie I-95

TownePlace Suites by Marriott Port St. Lucie I-95

TownePlace Suites by Marriott Port St. Lucie I-95
3.0 star property
Traditions, 13.5 km from St. Lucie Medical Center
9.4 out of 10, Exceptional, (1002)
"Room was clean, friendly staff and good complimentary breakfast"
United States
REX
The price is NZ$257
includes taxes & fees
3 Jan - 4 Jan 2026
TownePlace Suites by Marriott Port St. Lucie I-95
Outdoor pool, pool loungers
Best Western Downtown Stuart

Best Western Downtown Stuart

Best Western Downtown Stuart
3.0 star property
12.1 km from St. Lucie Medical Center
8.6 out of 10, Excellent, (1006)
"Staff were courteous, room was clean, breakfast was good."
United States
CRAIG
The price is NZ$257
includes taxes & fees
5 Jan - 6 Jan 2026
Best Western Downtown Stuart
Exterior
Hampton Inn & Suites Port St. Lucie, West

Hampton Inn & Suites Port St. Lucie, West

Hampton Inn & Suites Port St. Lucie, West
2.5 star property
11.4 km from St. Lucie Medical Center
8.8 out of 10, Excellent, (1008)
"Excellent staff from check in to check out! Excellent breakfast options! The room was very nice and spacious! "
United States
Victoria
The price is NZ$201
includes taxes & fees
25 Jan - 26 Jan 2026
Hampton Inn & Suites Port St. Lucie, West
Property amenity
Courtyard by Marriott Port St. Lucie Tradition

Courtyard by Marriott Port St. Lucie Tradition

Courtyard by Marriott Port St. Lucie Tradition
3.0 star property
Traditions, 13.6 km from St. Lucie Medical Center
9.4 out of 10, Exceptional, (489)
"Room was very clean and check in process was courteous and efficient. "
United States
Sandra
The price is NZ$274
includes taxes & fees
25 Jan - 26 Jan 2026
Courtyard by Marriott Port St. Lucie Tradition
Lobby
Mainstay Suites at PGA Village

Mainstay Suites at PGA Village

Mainstay Suites at PGA Village
2.5 star property
12.9 km from St. Lucie Medical Center
6.4 out of 10, (828)
"Everything was good"
United States
LIDIA
The price is NZ$143
includes taxes & fees
31 Dec - 1 Jan 2026
Mainstay Suites at PGA Village
Reception
Tru by Hilton Port St. Lucie Tradition

Tru by Hilton Port St. Lucie Tradition

Tru by Hilton Port St. Lucie Tradition
2.5 star property
Traditions, 13.6 km from St. Lucie Medical Center
9.2 out of 10, Wonderful, (764)
" I’ve stayed twice and it’s been an excellent experience. Clean facilities and great staff. "
United States
Daniel
The price is NZ$201
includes taxes & fees
4 Jan - 5 Jan 2026
Tru by Hilton Port St. Lucie Tradition
Outdoor pool
Hilton Garden Inn at PGA Village / Port St. Lucie

Hilton Garden Inn at PGA Village / Port St. Lucie

Hilton Garden Inn at PGA Village / Port St. Lucie
3.0 star property
12.8 km from St. Lucie Medical Center
8.8 out of 10, Excellent, (1004)
"The room was very clean and the staff was friendly and helpful"
United States
Alan
The price is NZ$236
includes taxes & fees
25 Jan - 26 Jan 2026
Hilton Garden Inn at PGA Village / Port St. Lucie
In-room safe, desk, laptop workspace, iron/ironing board
Holiday Inn Express & Suites Port St. Lucie West by IHG

Holiday Inn Express & Suites Port St. Lucie West by IHG

Holiday Inn Express & Suites Port St. Lucie West by IHG
2.5 star property
Saint Lucie West, 11.7 km from St. Lucie Medical Center
8.6 out of 10, Excellent, (1003)
"Clean room, quite, good breakfast made for a nice stay"
United States
Ronald
The price is NZ$205
includes taxes & fees
18 Jan - 19 Jan 2026
Holiday Inn Express & Suites Port St. Lucie West by IHG
Lobby
Sleep Inn Port St. Lucie at PGA Village

Sleep Inn Port St. Lucie at PGA Village

Sleep Inn Port St. Lucie at PGA Village
2.5 star property
12.9 km from St. Lucie Medical Center
6.4 out of 10, (370)
"very limited breakfast"
United States
Jerzy
The price is NZ$145
includes taxes & fees
25 Jan - 26 Jan 2026
Sleep Inn Port St. Lucie at PGA Village
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top St. Lucie Medical Center Hotel Reviews

Best Western Port St. Lucie

Best Western Port St. Lucie

10/10 Excellent
"Love this place. Great place with a lot of space."
Bradley 1-night trip
Posted 3 weeks ago
Best Western Port St. Lucie

Hotels near other St. Lucie Medical Center attractions

Drone photography of Veterans Memorial Park in Oldsmar, Florida, a waterside park featuring a memorial, a bocce court, fitness equipment, trails, and a gazebo in Tampa Bay

Veterans Memorial Park

4.2/5 (62 reviews)
You can find out about the history of Port Saint Lucie when you stop by Veterans Memorial Park. Stroll along the beautiful beaches or attend a sporting event in this culturally rich area.
See properties
View over Fort Pierce Inlet State Park on the Treasure Coast of Florida in St. Lucie County

St Lucie Inlet State Park

4.5/5 (15 reviews)
Find out about the history of Jensen Beach with a stop at St Lucie Inlet State Park. Wander through the beautiful beaches and waterfront in this culturally rich area.
See properties

Frequently asked questions

What's the area like around St. Lucie Medical Center?
St. Lucie Medical Center is located in Port Saint Lucie. If you're looking for a convenient place to stay, take a look at the 20 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay close to St. Lucie Medical Center?
Holiday Inn Port St. Lucie by IHG is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. It's located just a short 0.6 mi (1 km) from St. Lucie Medical Center. Another good choice is Best Western Port St. Lucie, located 2.7 mi (4.3 km) away.
How many hotels should I expect to find close to St. Lucie Medical Center?
Expedia has 20 hotels and other accommodation options within a mile from St. Lucie Medical Center.
If I need to cancel the hotel reservation for my stay near St. Lucie Medical Center, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you booked a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of your booking. Add your dates and click on "Search", then use the filter option "fully refundable" to review the best options available near St. Lucie Medical Center.
What can I see and do near St. Lucie Medical Center?
Local parks like Port St. Lucie Botanical Gardens, River Park Marina and Ocean Bay Beachside are peaceful spots to stop and take in some fresh air. Dip your toes in the water at Normandy Beach, Fort Pierce Beach and Herman's Bay Beach. Spend some time exploring the great outdoors at Veterans Memorial Park, Walton Scrub Preserve and Spruce Bluff Preserve.