Southern Indiana Holidays

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Our guide on where to stay in Southern Indiana

Find the best Southern Indiana areas and neighborhoods for the activities you enjoy most. Learn more about Southern Indiana
The entrance to the Kentucky Science Center with a large circular structure in the foreground.

West Main Historic District

A noteworthy feature of West Main Historic District is its fantastic nightlife. While you're in town, be sure to stop and check out Frazier International History Museum and Louisville Slugger Museum.

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A historic building with a prominent clock tower and dome, surrounded by trees and modern buildings.

Downtown Evansville

1 out of top 10 points of interest in this area

While visiting Downtown Evansville, you might make a stop by sights like Ford Center and Old National Events Plaza.

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A bridge with a metal truss structure and a highway with vehicles.

Portland

While visiting Portland, you might make a stop by sights like Portland Museum and Lannan Park Trailhead.

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A weathered tower with a metal sign reading "Better By Far" and a metal structure with the number "3" on top.

California

If you're spending some time in California, Ohio River Valley and Union Station are top sights worth seeing.

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An aerial view of a park with manicured lawns, a central fountain, and a large building with a red dome.

Downtown French Lick

Though Downtown French Lick may not have many top sights, you can venture to the surrounding area to see attractions like French Lick Springs Hotel and French Lick Casino.

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Southern Indiana Holiday

Our pick of the best Southern Indiana Hotel Deals

Radisson Hotel Louisville North

Radisson Hotel Louisville North

505 Marriott Drive Clarksville IN
NZ$120
13 Sept - 14 Sept
includes taxes & fees
7/10 Good! (3,384 reviews)
"The biggest thing is that the property was just simply nasty; everything was in rough condition. Aside from being in a rough part of town, the hotel is just not well maintained. I got a non-smoking room; I still occasionally smelled smoke. The room smelled terrible and i can only assume it made me ..."

Reviewed on 8 Sept 2026

Radisson Hotel Louisville North
Santas Lodge and Resort

Santas Lodge and Resort

91 W CHRISTMAS BLVD Santa Claus IN
Fully refundableReserve now, pay when you stay
NZ$192
17 Sept - 18 Sept
includes taxes & fees
Santas Lodge and Resort
Derby Hotel & Suites

Derby Hotel & Suites

505 K Marriot Dr Clarksville IN
NZ$79
9 Sept - 10 Sept
includes taxes & fees
7/10 Good! (195 reviews)
"Just became aware of that this was now a separate Hotel from Ramada. It's the same building it's just certain wings on the back side of the hotel. It's an older building but well maintained. The price was ridiculously low. Didn't have access to ramadas inside pool but they had a nice pool outside. ..."

Reviewed on 8 Sept 2026

Derby Hotel & Suites
See all 1,632 properties in Southern Indiana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Southern Indiana attractions

A river with a bridge, a stadium, and modern buildings.

KFC Yum Center

8.8/10 (1,621 reviews)
This waterfront arena hosts Louisville's premier sporting events and world-class concerts with 22,000 seats. Arrive early to explore downtown's culinary scene before experiencing the vibrant atmosphere inside.
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A water slide with a yellow and green inflatable raft carrying three people.
Photo by Indiana Office of Tourism Development

Holiday World and Splashin' Safari

9.4/10 (294 reviews)
Holiday World features themed holiday areas with thrilling coasters and water attractions. Enjoy complimentary soft drinks and sun cream while experiencing the world's longest water coaster, Wildebeest.
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A wall of wooden baseball bats organized by size and weight.

Louisville Slugger Museum

9.2/10 (2,299 reviews)
Step inside the world's only Louisville Slugger factory where baseball history comes alive. Watch craftsmen transform raw wood into iconic bats, then hold the same models used by legends like Babe Ruth and Derek Jeter.
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A wooden barrel room with barrels lined up on both sides and a wooden floor.

Whiskey Row

9.2/10 (11 reviews)
Learn about the local history of Louisville with a stop at Whiskey Row. Attend a sporting event or simply enjoy the lively bars while you're in the area.
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A city street with a large building labeled "FOURTH STREET" and a neon sign for "JIM BEAM."
Photo by Nura Mirzaliyeva

Fourth Street Live!

8.4/10 (2,560 reviews)
Louisville's premier entertainment district offers a vibrant mix of restaurants, bars, and live music venues. Savour diverse culinary experiences and dynamic nightlife in this pedestrian-friendly city centre hub.
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Kentucky International Convention Center

8.4/10 (763 reviews)
City centre Louisville's premier venue, KICC impresses with its modern glass design and light-filled spaces. Attend conventions, trade shows, and exhibitions in this state-of-the-art facility at the heart of the city.
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Ford Center

8.4/10 (472 reviews)
City centre Evansville's premier arena hosts Purple Aces basketball, Thunderbolts hockey, and major concerts. With cushioned seating for up to 11,000 spectators, it offers comfortable viewing and diverse concession options.
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Louisville Palace

8.2/10 (488 reviews)
You can make plans for a show at Louisville Palace during your stay in Louisville. Experience the area's acclaimed theatre scene or attend a sporting event.
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Frequently asked questions

How much does a Southern Indiana holiday package cost?
We make it simple to travel somewhere new, with Southern Indiana holiday packages starting from just . You'll have the flexibility to combine your preferred airlines, hotels and car rental. For the ultimate escape, why not add a few activities and tours to your itinerary?
How do I get a cheap travel package to Southern Indiana?
If you love bargains, combine your bookings into a Southern Indiana holiday package. Whether you're looking for flights, hotels, day tours or rental cars, you can book everything in one place. You'll have plenty of choice at your fingertips too. Expedia has over 550 airlines and 1 000 000 hotels around the globe to take your pick of. Fly with who you want, stay where you like and save a packet — now that's the ideal getaway!
Where should I stay in Southern Indiana?
Louisville is a fantastic place to explore. It draws in many travellers who come to see its top sights, like Churchill Downs and Muhammad Ali Centre.
What are the top hotels in Southern Indiana?
When it comes to properties in Louisville, Galt House Hotel Trademark Collection by Wyndham and Radisson Hotel Louisville Jeffersonville are two fantastic options. If you're also spending time in Jeffersonville - Clarksville, Radisson Hotel Louisville Jeffersonville and JW Marriott Indianapolis look forward to welcoming you.
How far in advance should I book my Southern Indiana holiday?
It all depends on the airline, but you can normally browse through international airfares on Expedia up to a year in advance. While it's a good idea to book ahead of time, lucky travellers will sometimes score a cheaper seat only weeks before the date of departure.
What does an Expedia Southern Indiana travel package include?
With Expedia, you can select any combination of flights, car rentals and hotels to create your ideal Southern Indiana travel package. Once you've made your booking, you can add on all the fun stuff like sightseeing tours and activities. Remember — the more you bundle, the greater the savings!
What should I know before booking a Southern Indiana travel package?
You'll save plenty with an Expedia travel package. Combine your airfares, rental cars and hotels and land fabulous discounts. Hotels aren't your only choice, though. Book with us and select from island resorts, rural cottages and everything in between!
Can I choose my airline with a Southern Indiana Expedia holiday package?
Expedia offers access to more than 550 partner airlines globally, so you certainly can. Simply select the carrier that suits you and create the perfect Southern Indiana trip.
If I'm not able to travel, can I cancel my Southern Indiana holiday package?
Yes, you can. We understand that even the best-laid plans can go awry, so we're here to help if you have to make changes to your Southern Indiana holiday package. You may be able to amend or cancel your itinerary at no cost if you've booked in the last 24 hours. Your hotel, airline or car rental company may impose a fee if your booking was made more than 24 hours ago. Have a look at our Customer Service Portal for more information. Also, be sure to check your itinerary for the finer details on change fees.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.